|
1
|
GLOBOCAN 2022: Bladder cancer 9th most
common worldwide-World Bladder Cancer Patient Coalition.
|
|
2
|
Leslie SW, Soon-Sutton TL and Aeddula NR:
Bladder cancer. In: StatPearls. StatPearls Publishing, Treasure
Island, FL, 2025.
|
|
3
|
Mushtaq J, Thurairaja R and Nair R:
Bladder cancer. Surgery (Oxford). 37:529–537. 2019.
|
|
4
|
van Kessel K: Personalized bladder cancer
management. Erasmus Universiteit Rotterdam (EUR), 2018.
|
|
5
|
Kamat AM and Black PC: Bladder cancer: A
practical guide. Springer International Publishing, Cham, 2021.
|
|
6
|
Heldin CH, Lu B, Evans R and Gutkind JS:
Signals and receptors. Cold Spring Harb Perspect Biol.
8(a005900)2016.
|
|
7
|
Khalil B, Miller EJ and Lappin SL:
Physiology, cellular receptors. In: StatPearls. StatPearls
Publishing, Treasure Island, FL, 2025.
|
|
8
|
Iqbal MJ, Kabeer A, Abbas Z, Siddiqui HA,
Calina D, Sharifi-Rad J and Cho WC: Interplay of oxidative stress,
cellular communication and signaling pathways in cancer. Cell
Commun Signal. 22(7)2024.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Hu H, Zhou H and Xu D: A review of the
effects and molecular mechanisms of dimethylcurcumin (ASC-J9) on
androgen receptor-related diseases. Chem Biol Drug Des. 97:821–835.
2021.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Estébanez-Perpiñá E, Bevan CL and McEwan
IJ: Eighty years of targeting androgen receptor activity in
prostate cancer: The fight goes on. Cancers (Basel).
13(509)2021.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Li P, Chen J and Miyamoto H: Androgen
receptor signaling in bladder cancer. Cancers (Basel).
9(20)2017.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Chen P, Li B and Ou-Yang L: Role of
estrogen receptors in health and disease. Front Endocrinol
(Lausanne). 13(839005)2022.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Eyster KM: The estrogen receptors: An
overview from different perspectives. Methods Mol Biol. 1366:1–10.
2016.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Joshi CJ, Ke W, Drangowska-Way A, O'Rourke
EJ and Lewis NE: What are housekeeping genes? PLoS Comput Biol.
18(e1010295)2022.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
16
|
White MC, Holman DM, Boehm JE, Peipins LA,
Grossman M and Henley SJ: Age and cancer risk: A potentially
modifiable relationship. Am J Prev Med. 46:S7–S15. 2014.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Al-Adilee MN and Al-Abassi HM: The Role of
Caspase-8, MLKL and RIPK1 in Iraqi Patients' women with breast
cancer. Al-Mustansiriyah J Sci. 36:22–33. 2025.
|
|
18
|
Rossi DJ, Jamieson CHM and Weissman IL:
Stems cells and the pathways to aging and cancer. Cell.
132:681–696. 2008.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Biagetti B and Puig-Domingo M: Age-related
hormones changes and its impact on health status and lifespan.
Aging Dis. 14:605–620. 2023.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Ganguly S, Naik D, Muskara A and Mian OY:
The nexus of endocrine signaling and cancer: How steroid hormones
influence genomic stability. Endocrinology.
162(bqaa177)2021.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Miyamoto H, Yang Z, Chen YT, Ishiguro H,
Uemura H, Kubota Y, Nagashima Y, Chang YJ, Hu YC, Tsai MY, et al:
Promotion of bladder cancer development and progression by androgen
receptor signals. J Natl Cancer Inst. 99:558–568. 2007.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Cao J, Yang X, Li J, Wu H, Li P, Yao Z,
Dong Z and Tian J: Screening and identifying immune-related cells
and genes in the tumor microenvironment of bladder urothelial
carcinoma: Based on TCGA database and bioinformatics. Front Oncol.
9(1533)2020.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Chen J, Huang CP, Quan C, Zu X, Ou Z, Tsai
YC, Messing E, Yeh S and Chang C: The androgen receptor in bladder
cancer. Nat Rev Urol. 20:560–574. 2023.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Sottnik JL, Vanderlinden L, Joshi M,
Chauca-Diaz A, Owens C, Hansel DE, Sempeck C, Ghosh D and
Theodorescu D: Androgen receptor regulates CD44 expression in
bladder cancer. Cancer Res. 81:2833–2846. 2021.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Lombard AP and Mudryj M: The emerging role
of the androgen receptor in bladder cancer. Endocrine-related
cancer. 22:R265–R277. 2015.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Rangel N, Rondon-Lagos M, Annaratone L,
Osella-Abate S, Metovic J, Mano MP, Bertero L, Cassoni P, Sapino A
and Castellano I: The role of the AR/ER ratio in ER-positive breast
cancer patients. Endocr Relat Cancer. 25:163–172. 2018.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Gucalp A, Tolaney S, Isakoff SJ, Ingle JN,
Liu MC, Carey LA, Blackwell K, Rugo H, Nabell L, Forero A, et al:
Phase II trial of bicalutamide in patients with androgen
receptor-positive, estrogen receptor-negative metastatic breast
cancer. Clin Cancer Res. 19:5505–5512. 2013.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Mashhadi R, Pourmand G, Kosari F, Mehrsai
A, Salem S, Pourmand MR, Alatab S, Khonsari M, Heydari F, Beladi L
and Alizadeh F: Role of steroid hormone receptors in formation and
progression of bladder carcinoma: A case-control study. Urol J.
11:1968–1973. 2014.PubMed/NCBI
|
|
29
|
Godoy G, Gakis G, Smith CL and Fahmy O:
Effects of androgen and estrogen receptor signaling pathways on
bladder cancer initiation and progression. Bladder Cancer.
2:127–137. 2016.PubMed/NCBI View Article : Google Scholar
|
|
30
|
de Brot S and Mongan NP: The cell cycle
and androgen signaling interactions in prostate cancer. In:
Precision Molecular Pathology of Prostate Cancer. Robinson BD,
Mosquera JM, Ro JY and Divatia M (eds). Springer International
Publishing, Cham, pp381-404, 2018.
|
|
31
|
Izumi K, Zheng Y, Li Y, Zaengle J and
Miyamoto H: Epidermal growth factor induces bladder cancer cell
proliferation through activation of the androgen receptor. Int J
Oncol. 41:1587–1592. 2012.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Izumi K, Mizokami A, Lin WJ, Lai KP and
Chang C: Androgen receptor roles in the development of benign
prostate hyperplasia. Am J Pathol. 182:1942–1949. 2013.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Goto T and Miyamoto H: The role of
estrogen receptors in urothelial cancer. Front Endocrinol
(Lausanne). 12(643870)2021.PubMed/NCBI View Article : Google Scholar
|
|
34
|
McGrath M, Michaud DS and De Vivo I:
Hormonal and reproductive factors and the risk of bladder cancer in
women. Am J Epidemiol. 163:236–244. 2006.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Wolpert BJ, Amr S, Ezzat S, Saleh D, Gouda
I, Loay I, Hifnawy T, Mikhail NN, Abdel-Hamid M, Zhan M, et al:
Estrogen exposure and bladder cancer risk in Egyptian women.
Maturitas. 67:353–357. 2010.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Davis-Dao CA, Henderson KD,
Sullivan-Halley J, Ma H, West D, Xiang YB, Gago-Dominguez M, Stern
MC, Castelao JE, Conti DV, et al: Lower risk in parous women
suggests that hormonal factors are important in bladder cancer
etiology. Cancer Epidemiol Biomarkers Prev. 20:1156–1170.
2011.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Miyamoto H, Yao JL, Chaux A, Zheng Y, Hsu
I, Izumi K, Chang C, Messing EM, Netto GJ and Yeh S: Expression of
androgen and oestrogen receptors and its prognostic significance in
urothelial neoplasm of the urinary bladder. BJU Int. 109:1716–1726.
2012.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Kontos S, Kominea A, Melachrinou M,
Balampani E and Sotiropoulou-Bonikou G: Inverse expression of
estrogen receptor-β and nuclear factor-κB in urinary bladder
carcinogenesis. Int J Urol. 17:801–809. 2010.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Flores-Estrada JJ, Jiménez A,
Victoria-Acosta G, Cortés-Malagón EM, Ortiz-López MG,
Alvarez-Sánchez ME, Nuñez-Olvera SI, Pérez-Navarro YF,
Morales-Reyna M and Puente-Rivera J: Nuclear receptors in bladder
cancer: Insights into miRNA-mediated regulation and potential
therapeutic implications. Int J Mol Sci. 26(7340)2025.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Ge Q, Lu M, Ju L, Qian K, Wang G, Wu CL,
Liu X, Xiao Y and Wang X: miR-4324-RACGAP1-STAT3-ESR1 feedback loop
inhibits proliferation and metastasis of bladder cancer. Int J
Cancer. 144:3043–3055. 2019.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Wu L, Zhang M, Qi L, Zu X, Li Y, Liu L,
Chen M, Li Y, He W, Hu X, et al: ERα-mediated alterations in
circ_0023642 and miR-490-5p signaling suppress bladder cancer
invasion. Cell Death Dis. 10(635)2019.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Ding M, Liu Y, Li J, Yao L, Liao X, Xie H,
Yang K, Zhou Q, Liu Y, Huang W and Cai Z: Oestrogen promotes
tumorigenesis of bladder cancer by inducing the enhancer
RNA-eGREB1. J Cell Mol Med. 22:5919–5927. 2018.PubMed/NCBI View Article : Google Scholar
|