|
1
|
Salman SA and Al-Jumaily RMK: Evaluation
of some immunological and DNA damage parameters among patients with
rheumatoid arthritis. Iraqi J Sci. 65:5439–5446. 2024.
|
|
2
|
Bhayani HR and Hedrick SM: The role of
polymorphic amino acids of the MHC molecule in the selection of the
T cell repertoire. J Immunol. 146:1093–1098. 1991.PubMed/NCBI
|
|
3
|
Alves CC, Lewis J, Antunes DA and Donadi
EA: The role of vimentin peptide citrullination in the structure
and dynamics of HLA-DRB1 rheumatoid arthritis risk-associated
alleles. Int J Mol Sci. 26(34)2024.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Lim JJ, Jones CM, Loh TJ, Ting YT, Zareie
P, Loh KL, Felix NJ, Suri A, McKinnon M, Stevenaert F, et al: The
shared susceptibility epitope of HLA-DR4 binds citrullinated
self-antigens and the TCR. Sci Immunol. 6(eabe0896)2021.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Yousif NH and Ibraheem SR: Comparison of
some physiological parameters in female rheumatoid arthritis
patients in pre- and postmenopausal stages. Iraqi J Sci.
61:1926–1931. 2020.
|
|
6
|
Meng W, Zhu Z, Jiang X, Too CL, Uebe S,
Jagodic M, Kockum I, Murad S, Ferrucci L, Alfredsson L, et al: DNA
methylation mediates genotype and smoking interaction in the
development of anti-citrullinated peptide antibody-positive
rheumatoid arthritis. Arthritis Res Ther. 19(71)2017.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Mahdi H, Fisher BA, Källberg H, Plant D,
Malmström V, Rönnelid J, Charles P, Ding B, Alfredsson L, Padyukov
L, et al: Specific interaction between genotype, smoking and
autoimmunity to citrullinated alpha-enolase in the etiology of
rheumatoid arthritis. Nat Genet. 41:1319–1324. 2009.PubMed/NCBI View
Article : Google Scholar
|
|
8
|
Mourad J, Naji S, El Karaaoui A and Wahbeh
D: Association of HLA-DRB1 alleles with rheumatoid arthritis in
Mediterranean populations: A meta-analysis with regional
differences, advanced heterogeneity and evidence quality
assessment. medRxiv: 04.29.25326652, 2025.
|
|
9
|
Al-Saffar EA, Al-Saadi BQH and Awadh NI:
Study the association of miRNA-146a gene polymorphism and some
immunological markers with the risk of rheumatoid arthritis
incidence in a sample of Iraqi patients. Rev Bionatura. 8:1–14.
2023.
|
|
10
|
Li C, Zhang Y, Song H, Gao J, Zhao DB, Zhu
Q, He DY, Wang L, Li XP, Liu XD, et al: Anti-cyclic citrullinated
peptide antibody predicts the development of rheumatoid arthritis
in patients with undifferentiated arthritis. Chin Med J (Engl).
123:2899–2904. 2019.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Oglah AA, AbidMohammed KI and Alosami MH:
Prognostic value of COMP a comparison with ACCP in rheumatoid
arthritis patients in Iraq. Int J Health Sci. 6:937–948. 2022.
|
|
12
|
Larid G, Pancarte M, Offer G, Clavel C,
Martin M, Pradel V, Auger I, Lafforgue P, Roudier J, Serre G and
Balandraud N: In rheumatoid arthritis patients, HLA-DRB1*04:01 and
rheumatoid nodules are associated with ACPA to a particular fibrin
epitope. Front Immunol. 12(692041)2021.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Mole EN, Tarassi K, Tsirogianni A,
Athanassiades T, Kitsiou V, Kouniaki D, Gazi S and
Vlachoyiannopoulos P: Impact of HLA-DRB1 SE, anti-citrullinated
protein antibodies and smoking on radiographic outcome in Greek
patients with Rheumatoid Arthritis. BMC Rheumatol.
9(128)2025.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Arnett FC, Edworthy SM, Bloch DA, McShane
DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS,
et al: The American Rheumatism Association 1987 revised criteria
for the classification of rheumatoid arthritis. Arthritis Rheum.
31:315–324. 1988.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Pisaniello HL, Whittle SL, Lester S, Menz
F, Metcalf R, McWilliams L, Hill CL and Proudman S: Using the
derived 28-joint disease activity score patient-reported components
(DAS28-P) index as a discriminatory measure of response to
disease-modifying anti-rheumatic drug therapy in early rheumatoid
arthritis. BMC Rheumatol. 6(67)2022.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Parasannanavar DJ, Yeola A, Pradhan V,
Rajyadhaksha A and Ghosh K: HLA-DRβ1*04 typing by simple in-house
PCR-SSP technique for rheumatoid arthritis patients. Rheumatol Int.
33:867–870. 2013.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Forthofer RN and Lee ES: Introduction to
biostatistics: A guide to design, analysis, and discovery.
Elsevier, 2014.
|
|
19
|
Zhao M, Mauer L, Sayles H, Cannon GW,
Reimold A, Kerr GS, Baker JF, Thiele GM, England BR and Mikuls TR:
HLA-DRB1 haplotypes, shared epitope, and disease outcomes in US
veterans with rheumatoid arthritis. J Rheumatol. 46:685–693.
2019.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Roudier J, Balandraud N and Auger I: How
RA associated HLA-DR molecules contribute to the development of
antibodies to citrullinated proteins: The hapten carrier model.
Front Immunol. 13(930112)2022.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Fu J, Nogueira SV, Drongelen VV, Coit P,
Ling S, Rosloniec EF, Sawalha AH and Holoshitz J: Shared
epitope-aryl hydrocarbon receptor crosstalk underlies the mechanism
of gene-environment interaction in autoimmune arthritis. Proc Natl
Acad Sci USA. 115:4755–4760. 2018.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Soliman AF, Egaila SES, Ali AI, Azab NI
and Al-Gohary HH: HLA-DRB1 alleles in Egyptian rheumatoid arthritis
patients: Relations to anti-cyclic citrullinated peptide
antibodies, disease activity and severity. Egypt Rheumatol.
38:269–275. 2016.
|
|
23
|
Al-Yasiri IK, Al-Mousawi JK and Al-Mohana
AM: Evaluation of some genetic factors in rheumatoid arthritis
patients in Iraq. Iraqi J Biotechnol. 13:66–74. 2013.
|
|
24
|
Aljoboury BA, Alta'ee AH and Alrubaie SJ:
Association of HLA-DRB1 gene polymorphism in rheumatoid arthritis
patients in Babylon Province, Iraq. Indian J Forensic Med Toxicol.
14:855–860. 2020.
|
|
25
|
del Rincón I, Battafarano DF, Arroyo RA,
Murphy FT and Escalante A: Heterogeneity between men and women in
the influence of the HLA-DRB1 shared epitope on the clinical
expression of rheumatoid arthritis. Arthritis Rheum. 46:1480–1488.
2002.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Albarzinji N, Ismael SA and Albustany D:
Association of rheumatoid arthritis and its severity with human
leukocytic antigen-DRB1 alleles in Kurdish region in North of Iraq.
BMC Rheumatol. 6(4)2022.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Castro F, Acevedo E, Ciusani E, Angulo JA,
Wollheim FA and Sandberg-Wollheim M: Tumour necrosis factor
microsatellites and HLA-DRB1*, HLA-DQA1*, and HLA-DQB1* alleles in
Peruvian patients with rheumatoid arthritis. Ann Rheum Dis.
60:791–795. 2001.PubMed/NCBI View Article : Google Scholar
|
|
28
|
England BR, Sayles H, Michaud K, Caplan L,
Davis LA, Cannon GW, Sauer BC, Solow EB, Reimold AM, Kerr GS, et
al: Cause-specific mortality in male US veterans with rheumatoid
arthritis. Arthritis Care Res (Hoboken). 68:36–45. 2016.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Jiang X, Trouw LA, van Wesemael TJ, Shi J,
Bengtsson C, Källberg H, Malmström V, Israelsson L, Hreggvidsdottir
H, Verduijn W, et al: Anti-CarP antibodies in two large cohorts of
patients with rheumatoid arthritis and their relationship to
genetic risk factors, cigarette smoking and other autoantibodies.
Ann Rheum Dis. 73:1761–1768. 2014.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Zhuo J, Xia Q, Sharma N, Gao S, Lama S,
Cui J, Feathers V, Shadick N and Weinblatt ME: The role of shared
epitope in rheumatoid arthritis prognosis in relation to
anti-citrullinated protein antibody positivity. Rheumatol Ther.
9:637–647. 2022.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Romão VC and Fonseca JE: Etiology and risk
factors for rheumatoid arthritis: A state-of-the-art review. Front
Med (Lausanne). 8(689698)2021.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Wu CY, Yang HY and Lai JH:
Anti-citrullinated protein antibodies in patients with rheumatoid
arthritis: Biological effects and mechanisms of immunopathogenesis.
Int J Mol Sci. 21(4015)2020.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Jung SM, Park YJ, Park KS and Kim KJ:
Clinical implications of shared epitope and anti-citrullinated
peptide antibody in patients with rheumatoid arthritis. J Rheum
Dis. 29:171–180. 2022.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Karlson EW, Chang SC, Cui J, Chibnik LB,
Fraser PA, De Vivo I and Costenbader KH: Gene-environment
interaction between HLA-DRB1 shared epitope and heavy cigarette
smoking in predicting incident rheumatoid arthritis. Ann Rheum Dis.
69:54–60. 2010.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Roh S: Smoking as a preventable risk
factor for rheumatoid arthritis: Rationale for smoking cessation
treatment in patients with rheumatoid arthritis. J Rheum Dis.
26:12–19. 2019.
|
|
36
|
Hirose W, Harigai M, Amano K, Hidaka T,
Itoh K, Aoki K, Nakashima M, Nagasawa H, Komano Y and Nanki T:
TOF-ABT Study Group. Impact of the HLA-DRB1 shared epitope on
responses to treatment with tofacitinib or abatacept in patients
with rheumatoid arthritis. Arthritis Res Ther.
23(228)2021.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Wysocki T, Onska M and Paradowska-Gorycka
A: Current understanding of an emerging role of HLA-DRB1 gene in
rheumatoid arthritis-from research to clinical practice. Cells.
9(1127)2020.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Ishikawa Y and Terao C: The impact of
cigarette smoking on risk of rheumatoid arthritis: A narrative
review. Cells. 9(475)2020.PubMed/NCBI View Article : Google Scholar
|