Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis

  • Authors:
    • Jiakai Li
    • Chuangui Li
    • Jiaojiao Li
  • View Affiliations

  • Published online on: May 11, 2018     https://doi.org/10.3892/etm.2018.6154
  • Pages: 413-419
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Abstract

The aim of the present study was to investigate the computed tomography (CT) manifestations of Wegener granulomatosis (WG) in the chest and potential reasons for misdiagnosis. Conventional CT scans and clinical data of 45 patients with WG were retrospectively analyzed. Patients typically presented with multiple system involvement, primarily in the upper and lower respiratory tract. The incidence of thoracic involvement was 75.56% (34/45). Radiographic features were varied between cases in the present study, with the most common features being numerous cavitary nodules and masses in the lungs. Cavitations were usually irregular, with uneven wall thickness, partial centrality, fuzzy inner edges and piecemeal necrosis. These results indicate that WG typically has multiple system involvement, with the chest being most prominent. Multiple variable‑sized cavitary nodules with irregular edges and piecemeal necrosis were the most notable features revealed using CT scanning; however, in order to give a definitive diagnosis, biopsies should be performed.
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July-2018
Volume 16 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Li J, Li C and Li J: Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis. Exp Ther Med 16: 413-419, 2018
APA
Li, J., Li, C., & Li, J. (2018). Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis. Experimental and Therapeutic Medicine, 16, 413-419. https://doi.org/10.3892/etm.2018.6154
MLA
Li, J., Li, C., Li, J."Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis". Experimental and Therapeutic Medicine 16.1 (2018): 413-419.
Chicago
Li, J., Li, C., Li, J."Thoracic manifestation of Wegener's granulomatosis: Computed tomography findings and analysis of misdiagnosis". Experimental and Therapeutic Medicine 16, no. 1 (2018): 413-419. https://doi.org/10.3892/etm.2018.6154