Current bioinformatics tools in genomic biomedical research (Review)

  • Authors:
    • Andreas Teufel
    • Markus Krupp
    • Arndt Weinmann
    • Peter R. Galle
  • View Affiliations

  • Published online on: June 1, 2006     https://doi.org/10.3892/ijmm.17.6.967
  • Pages: 967-973
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Abstract

On the advent of a completely assembled human genome, modern biology and molecular medicine stepped into an era of increasingly rich sequence database information and high-throughput genomic analysis. However, as sequence entries in the major genomic databases currently rise exponentially, the gap between available, deposited sequence data and analysis by means of conventional molecular biology is rapidly widening, making new approaches of high-throughput genomic analysis necessary. At present, the only effective way to keep abreast of the dramatic increase in sequence and related information is to apply biocomputational approaches. Thus, over recent years, the field of bioinformatics has rapidly developed into an essential aid for genomic data analysis and powerful bioinformatics tools have been developed, many of them publicly available through the World Wide Web. In this review, we summarize and describe the basic bioinformatics tools for genomic research such as: genomic databases, genome browsers, tools for sequence alignment, single nucleotide polymorphism (SNP) databases, tools for ab initio gene prediction, expression databases, and algorithms for promoter prediction.

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June 2006
Volume 17 Issue 6

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Teufel A, Krupp M, Weinmann A and Galle PR: Current bioinformatics tools in genomic biomedical research (Review). Int J Mol Med 17: 967-973, 2006
APA
Teufel, A., Krupp, M., Weinmann, A., & Galle, P.R. (2006). Current bioinformatics tools in genomic biomedical research (Review). International Journal of Molecular Medicine, 17, 967-973. https://doi.org/10.3892/ijmm.17.6.967
MLA
Teufel, A., Krupp, M., Weinmann, A., Galle, P. R."Current bioinformatics tools in genomic biomedical research (Review)". International Journal of Molecular Medicine 17.6 (2006): 967-973.
Chicago
Teufel, A., Krupp, M., Weinmann, A., Galle, P. R."Current bioinformatics tools in genomic biomedical research (Review)". International Journal of Molecular Medicine 17, no. 6 (2006): 967-973. https://doi.org/10.3892/ijmm.17.6.967