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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2009 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells

Lloyd F. Alfonso, Kalkunte S. Srivenugopal, Thiruma V. Arumugam, Thomas J. Abbruscato, Jon A. Weidanz, G. Jayarama Bhat
Pages: 597-608
Published online on: 01 March 2009

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Article

Phase I study of a new radiosensitizer containing hydrogen peroxide and sodium hyaluronate for topical tumor injection: A new enzyme-targeting radiosensitization treatment, Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas, Type II (KORTUC II)

Yasuhiro Ogawa, Kei Kubota, Hironobu Ue, Yuko Kataoka, Michiko Tadokoro, Kana Miyatake, Kazuhiro Tsuzuki, Tomoaki Yamanishi, Satoshi Itoh, Jiro Hitomi, Norihiko Hamada, Shinji Kariya, Mitsutaka Fukumoto, Akihito Nishioka, Taisuke Inomata
Pages: 609-618
Published online on: 01 March 2009

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Article

Human mesenchymal stem cells from bone marrow express tumor endothelial and stromal markers

Rebecca G. Bagley, William Weber, Cecile Rouleau, Min Yao, Nakayuki Honma, Shiro Kataoka, Isao Ishida, Bruce L. Roberts, Beverly A. Teicher
Pages: 619-627
Published online on: 01 March 2009

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Article

The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responses

Anita Schmitt, Thomas F.E. Barth, Eva Beyer, Franziska Borchert, Markus Rojewski, Jinfei Chen, Philippe Guillaume, Silke Gronau, Jochen Greiner, Peter Möller, Herbert Riechelmann, Michael Schmitt
Pages: 629-639
Published online on: 01 March 2009

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Article

Decrease in chemosensitivity against anticancer drugs by an esophageal squamous cell carcinoma SEREX antigen, AISEC

Takaki Hiwasa, Hideaki Shimada, Mari Kuboshima, Tooru Shiratori, Akiko Kagaya, Yoshihiro Nabeya, Sumio Sugano, Takenori Ochiai, Hisahiro Matsubara, Masaki Takiguchi
Pages: 641-648
Published online on: 01 March 2009

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Article

Glypican-3 is a useful diagnostic marker for a component of hepatocellular carcinoma in human liver cancer

Hirofumi Shirakawa, Toshimitsu Kuronuma, Yoshiko Nishimura, Takahiro Hasebe, Masayuki Nakano, Naoto Gotohda, Shinichiro Takahashi, Toshio Nakagohri, Masaru Konishi, Nobuaki Kobayashi, Taira Kinoshita, Tetsuya Nakatsura
Pages: 649-656
Published online on: 01 March 2009

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Article

Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression

Masami Watanabe, Yuji Kashiwakura, Peng Huang, Kazuhiko Ochiai, Junichiro Futami, Shun-Ai Li, Munenori Takaoka, Yasutomo Nasu, Masakiyo Sakaguchi, Nam-Ho Huh, Hiromi Kumon
Pages: 657-663
Published online on: 01 March 2009

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Article

Expression of CXCL12 on pseudopalisading cells and proliferating microvessels in glioblastomas: An accelerated growth factor in glioblastomas

Hideki Komatani, Yasuo Sugita, Fumiko Arakawa, Koichi Ohshima, Minoru Shigemori
Pages: 665-672
Published online on: 01 March 2009

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Article Open Access

VEGF-C and VEGF-D expression is correlated with lymphatic vessel density and lymph node metastasis in oral squamous cell carcinoma: Implications for use as a prognostic marker

Tsuyoshi Sugiura, Yoshiko Inoue, Ryosuke Matsuki, Kotaro Ishii, Miho Takahashi, Masakazu Abe, Kanemitsu Shirasuna
Pages: 673-680
Published online on: 01 March 2009

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Article

Expression of CIITA-related MHCII molecules in tumors linked to prognosis in hepatocellular carcinoma

Xing-Wang Xie, Ming-Hui Mei, Wei-Jia Liao, Li-Hua Qian, Xin Yu, Ran Fei, Li-Ling Qin, Heng-Hui Zhang, Ji-Run Peng, Dan-Hua Shen, Lai Wei, Hong-Song Chen
Pages: 681-688
Published online on: 01 March 2009

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Article

Synergistic cell growth inhibition by the combination of amrubicin and Akt-suppressing tyrosine kinase inhibitors in small cell lung cancer cells: Implication of c-Src and its inhibitor

Yasuto Ueda, Tadashi Igishi, Kiyoshi Hashimoto, Hisashi Suyama, Kunio Araki, Takashi Sumikawa, Kenichi Takeda, Hirofumi Nakazaki, Keiji Matsunami, Masahiro Kodani, Yasushi Shigeoka, Shingo Matsumoto, Eiji Shimizu
Pages: 689-696
Published online on: 01 March 2009

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Article

The Phox2 pathway is differentially expressed in neuroblastoma tumors, but no mutations were found in the candidate tumor suppressor gene PHOX2A

Annica Wilzén, Staffan Nilsson, Rose-Marie Sjöberg, Per Kogner, Tommy Martinsson, Frida Abel
Pages: 697-705
Published online on: 01 March 2009

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Article

Downregulation of SPARC expression inhibits cell migration and invasion in malignant gliomas

Toshimoto Seno, Hironobu Harada, Shohei Kohno, Mikio Teraoka, Akihiro Inoue, Takanori Ohnishi
Pages: 707-715
Published online on: 01 March 2009

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Article

Cancer stem cells from human glioma cell line are resistant to Fas-induced apoptosis

Julian Bertrand, Gaëlle Begaud-Grimaud, Barbara Bessette, Mireille Verdier, Serge Battu, Marie-Odile Jauberteau
Pages: 717-727
Published online on: 01 March 2009

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Article

Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy

Ilya V. Ulasov, Mathew A. Tyler, Zeng B. Zhu, Yu Han, Tong-Chuan He, Maciej S. Lesniak
Pages: 729-742
Published online on: 01 March 2009

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Article Open Access

Mifepristone abrogates repopulation of ovarian cancer cells in between courses of cisplatin treatment

Elizabeth M. Freeburg, Alicia A. Goyeneche, Carlos M. Telleria
Pages: 743-755
Published online on: 01 March 2009

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Article

Retinoids induce differentiation and downregulate telomerase activity and N-Myc to increase sensitivity to flavonoids for apoptosis in human malignant neuroblastoma SH-SY5Y cells

Arabinda Das, Naren L. Banik, Swapan K. Ray
Pages: 757-765
Published online on: 01 March 2009

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Article

Overexpression of PIK3CA is associated with lymph node metastasis in esophageal squamous cell carcinoma

Ichiro Akagi, Masao Miyashita, Hiroshi Makino, Tsutomu Nomura, Nobutoshi Hagiwara, Ken Takahashi, Kazumitsu Cho, Takuya Mishima, Osamu Ishibashi, Toshikazu Ushijima, Toshihiro Takizawa, Takashi Tajiri
Pages: 767-775
Published online on: 01 March 2009

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Article

Strawberry polyphenols are equally cytotoxic to tumourigenic and normal human breast and prostate cell lines

Jennifer Weaver, Tina Briscoe, Mimi Hou, Chris Goodman, Slawomir Kata, Heather Ross, Gordon McDougall, Derek Stewart, Andrew Riches
Pages: 777-786
Published online on: 01 March 2009

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Article

Copy number changes can be a predictor for hemoglobin reduction after S-1 monotherapy in gastric cancer

Hei Cheul Jeung, Sun Young Rha, Chan Hee Park, Chong-Kun Im, Sang Joon Shin, Joong Bae Ahn, Sung Hoon Noh, Jae Kyung Roh, Hyun Cheol Chung
Pages: 787-796
Published online on: 01 March 2009

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Article

The expression of epidermal growth factor receptor and its downstream signaling molecules in osteosarcoma

Sung-Im Do, Woon Won Jung, Hyun Sook Kim, Yong-Koo Park
Pages: 797-803
Published online on: 01 March 2009

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Article

Prostaglandin E2 receptor 2 overexpression in squamous cell carcinoma of the lung correlates with p16INK4A methylation and an unfavorable prognosis

Mohamed Alaa, Makoto Suzuki, Mitsuru Yoshino, Lei Tian, Hidemi Suzuki, Kaoru Nagato, Taiki Fujiwara, Hironobu Wada, Yasumitsu Moriya, Hidehisa Hoshino, Shinichiro Motohashi, Shigetoshi Yoshida, Kiyoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Aliae Abdrabou, Maha Elkholy, Tarek Mahfouz, Ichiro Yoshino
Pages: 805-812
Published online on: 01 March 2009

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Article

Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models

Chris Van Bree, Angeliqué D. Barten-Van Rijbroek, René Leen, Hans M. Rodermond, André B.P. Van Kuilenburg, Henk B. Kal
Pages: 813-819
Published online on: 01 March 2009

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Article

Circulating levels of periostin may help identify patients with more aggressive colorectal cancer

Qi-Wen Ben, Zhen Zhao, Sheng-Fang Ge, Jie Zhou, Fei Yuan, Yao-Zong Yuan
Pages: 821-828
Published online on: 01 March 2009

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Article

Role of Hedgehog signaling pathway in proliferation and invasiveness of hepatocellular carcinoma cells

Wei-Ting Cheng, Kai Xu, De-Ying Tian, Zheng-Gang Zhang, Li-Jiang Liu, Ying Chen
Pages: 829-836
Published online on: 01 March 2009

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Article

Prediction of high-risk patients by genome-wide copy number alterations from remaining cancer after neoadjuvant chemotherapy and surgery

Sun Young Rha, Hei Cheul Jeung, Min Young Seo, Sang Cheol Kim, Woo Ick Yang, Yong Wha Moon, Hyun Cheol Chung
Pages: 837-846
Published online on: 01 March 2009

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Article

Expression of prostaglandin E2 receptors in oral squamous cell carcinomas and growth inhibitory effects of an EP3 selective antagonist, ONO-AE3-240

Hiroshi Hoshikawa, Rieko Goto, Terushige Mori, Tomoo Mitani, Nozomu Mori
Pages: 847-852
Published online on: 01 March 2009

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Article

The inhibitory effect of the proinflammatory cytokine TNFα on erythroid differentiation involves erythroid transcription factor modulation

Isabelle Buck, Franck Morceau, Silvia Cristofanon, Simone Reuter, Mario Dicato, Marc Diederich
Pages: 853-860
Published online on: 01 March 2009

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Article

Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells

Pedro Miguel Lacal, Lucio Tentori, Alessia Muzi, Federica Ruffini, Annalisa Susanna Dorio, Weizheng Xu, Diego Arcelli, Jie Zhang, Grazia Graziani
Pages: 861-872
Published online on: 01 March 2009

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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