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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2009 Volume 34 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells

Lloyd F. Alfonso, Kalkunte S. Srivenugopal, Thiruma V. Arumugam, Thomas J. Abbruscato, Jon A. Weidanz, G. Jayarama Bhat
Pages: 597-608
Published online on: 01 March 2009

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Article

Phase I study of a new radiosensitizer containing hydrogen peroxide and sodium hyaluronate for topical tumor injection: A new enzyme-targeting radiosensitization treatment, Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas, Type II (KORTUC II)

Yasuhiro Ogawa, Kei Kubota, Hironobu Ue, Yuko Kataoka, Michiko Tadokoro, Kana Miyatake, Kazuhiro Tsuzuki, Tomoaki Yamanishi, Satoshi Itoh, Jiro Hitomi, Norihiko Hamada, Shinji Kariya, Mitsutaka Fukumoto, Akihito Nishioka, Taisuke Inomata
Pages: 609-618
Published online on: 01 March 2009

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Article

Human mesenchymal stem cells from bone marrow express tumor endothelial and stromal markers

Rebecca G. Bagley, William Weber, Cecile Rouleau, Min Yao, Nakayuki Honma, Shiro Kataoka, Isao Ishida, Bruce L. Roberts, Beverly A. Teicher
Pages: 619-627
Published online on: 01 March 2009

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Article

The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responses

Anita Schmitt, Thomas F.E. Barth, Eva Beyer, Franziska Borchert, Markus Rojewski, Jinfei Chen, Philippe Guillaume, Silke Gronau, Jochen Greiner, Peter Möller, Herbert Riechelmann, Michael Schmitt
Pages: 629-639
Published online on: 01 March 2009

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Article

Decrease in chemosensitivity against anticancer drugs by an esophageal squamous cell carcinoma SEREX antigen, AISEC

Takaki Hiwasa, Hideaki Shimada, Mari Kuboshima, Tooru Shiratori, Akiko Kagaya, Yoshihiro Nabeya, Sumio Sugano, Takenori Ochiai, Hisahiro Matsubara, Masaki Takiguchi
Pages: 641-648
Published online on: 01 March 2009

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Article

Glypican-3 is a useful diagnostic marker for a component of hepatocellular carcinoma in human liver cancer

Hirofumi Shirakawa, Toshimitsu Kuronuma, Yoshiko Nishimura, Takahiro Hasebe, Masayuki Nakano, Naoto Gotohda, Shinichiro Takahashi, Toshio Nakagohri, Masaru Konishi, Nobuaki Kobayashi, Taira Kinoshita, Tetsuya Nakatsura
Pages: 649-656
Published online on: 01 March 2009

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Article

Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression

Masami Watanabe, Yuji Kashiwakura, Peng Huang, Kazuhiko Ochiai, Junichiro Futami, Shun-Ai Li, Munenori Takaoka, Yasutomo Nasu, Masakiyo Sakaguchi, Nam-Ho Huh, Hiromi Kumon
Pages: 657-663
Published online on: 01 March 2009

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Article

Expression of CXCL12 on pseudopalisading cells and proliferating microvessels in glioblastomas: An accelerated growth factor in glioblastomas

Hideki Komatani, Yasuo Sugita, Fumiko Arakawa, Koichi Ohshima, Minoru Shigemori
Pages: 665-672
Published online on: 01 March 2009

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Article Open Access

VEGF-C and VEGF-D expression is correlated with lymphatic vessel density and lymph node metastasis in oral squamous cell carcinoma: Implications for use as a prognostic marker

Tsuyoshi Sugiura, Yoshiko Inoue, Ryosuke Matsuki, Kotaro Ishii, Miho Takahashi, Masakazu Abe, Kanemitsu Shirasuna
Pages: 673-680
Published online on: 01 March 2009

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Article

Expression of CIITA-related MHCII molecules in tumors linked to prognosis in hepatocellular carcinoma

Xing-Wang Xie, Ming-Hui Mei, Wei-Jia Liao, Li-Hua Qian, Xin Yu, Ran Fei, Li-Ling Qin, Heng-Hui Zhang, Ji-Run Peng, Dan-Hua Shen, Lai Wei, Hong-Song Chen
Pages: 681-688
Published online on: 01 March 2009

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Article

Synergistic cell growth inhibition by the combination of amrubicin and Akt-suppressing tyrosine kinase inhibitors in small cell lung cancer cells: Implication of c-Src and its inhibitor

Yasuto Ueda, Tadashi Igishi, Kiyoshi Hashimoto, Hisashi Suyama, Kunio Araki, Takashi Sumikawa, Kenichi Takeda, Hirofumi Nakazaki, Keiji Matsunami, Masahiro Kodani, Yasushi Shigeoka, Shingo Matsumoto, Eiji Shimizu
Pages: 689-696
Published online on: 01 March 2009

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Article

The Phox2 pathway is differentially expressed in neuroblastoma tumors, but no mutations were found in the candidate tumor suppressor gene PHOX2A

Annica Wilzén, Staffan Nilsson, Rose-Marie Sjöberg, Per Kogner, Tommy Martinsson, Frida Abel
Pages: 697-705
Published online on: 01 March 2009

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Article

Downregulation of SPARC expression inhibits cell migration and invasion in malignant gliomas

Toshimoto Seno, Hironobu Harada, Shohei Kohno, Mikio Teraoka, Akihiro Inoue, Takanori Ohnishi
Pages: 707-715
Published online on: 01 March 2009

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Article

Cancer stem cells from human glioma cell line are resistant to Fas-induced apoptosis

Julian Bertrand, Gaëlle Begaud-Grimaud, Barbara Bessette, Mireille Verdier, Serge Battu, Marie-Odile Jauberteau
Pages: 717-727
Published online on: 01 March 2009

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Article

Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy

Ilya V. Ulasov, Mathew A. Tyler, Zeng B. Zhu, Yu Han, Tong-Chuan He, Maciej S. Lesniak
Pages: 729-742
Published online on: 01 March 2009

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Article Open Access

Mifepristone abrogates repopulation of ovarian cancer cells in between courses of cisplatin treatment

Elizabeth M. Freeburg, Alicia A. Goyeneche, Carlos M. Telleria
Pages: 743-755
Published online on: 01 March 2009

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Article

Retinoids induce differentiation and downregulate telomerase activity and N-Myc to increase sensitivity to flavonoids for apoptosis in human malignant neuroblastoma SH-SY5Y cells

Arabinda Das, Naren L. Banik, Swapan K. Ray
Pages: 757-765
Published online on: 01 March 2009

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Article

Overexpression of PIK3CA is associated with lymph node metastasis in esophageal squamous cell carcinoma

Ichiro Akagi, Masao Miyashita, Hiroshi Makino, Tsutomu Nomura, Nobutoshi Hagiwara, Ken Takahashi, Kazumitsu Cho, Takuya Mishima, Osamu Ishibashi, Toshikazu Ushijima, Toshihiro Takizawa, Takashi Tajiri
Pages: 767-775
Published online on: 01 March 2009

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Article

Strawberry polyphenols are equally cytotoxic to tumourigenic and normal human breast and prostate cell lines

Jennifer Weaver, Tina Briscoe, Mimi Hou, Chris Goodman, Slawomir Kata, Heather Ross, Gordon McDougall, Derek Stewart, Andrew Riches
Pages: 777-786
Published online on: 01 March 2009

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Article

Copy number changes can be a predictor for hemoglobin reduction after S-1 monotherapy in gastric cancer

Hei Cheul Jeung, Sun Young Rha, Chan Hee Park, Chong-Kun Im, Sang Joon Shin, Joong Bae Ahn, Sung Hoon Noh, Jae Kyung Roh, Hyun Cheol Chung
Pages: 787-796
Published online on: 01 March 2009

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Article

The expression of epidermal growth factor receptor and its downstream signaling molecules in osteosarcoma

Sung-Im Do, Woon Won Jung, Hyun Sook Kim, Yong-Koo Park
Pages: 797-803
Published online on: 01 March 2009

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Article

Prostaglandin E2 receptor 2 overexpression in squamous cell carcinoma of the lung correlates with p16INK4A methylation and an unfavorable prognosis

Mohamed Alaa, Makoto Suzuki, Mitsuru Yoshino, Lei Tian, Hidemi Suzuki, Kaoru Nagato, Taiki Fujiwara, Hironobu Wada, Yasumitsu Moriya, Hidehisa Hoshino, Shinichiro Motohashi, Shigetoshi Yoshida, Kiyoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Aliae Abdrabou, Maha Elkholy, Tarek Mahfouz, Ichiro Yoshino
Pages: 805-812
Published online on: 01 March 2009

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Article

Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models

Chris Van Bree, Angeliqué D. Barten-Van Rijbroek, René Leen, Hans M. Rodermond, André B.P. Van Kuilenburg, Henk B. Kal
Pages: 813-819
Published online on: 01 March 2009

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Article

Circulating levels of periostin may help identify patients with more aggressive colorectal cancer

Qi-Wen Ben, Zhen Zhao, Sheng-Fang Ge, Jie Zhou, Fei Yuan, Yao-Zong Yuan
Pages: 821-828
Published online on: 01 March 2009

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Article

Role of Hedgehog signaling pathway in proliferation and invasiveness of hepatocellular carcinoma cells

Wei-Ting Cheng, Kai Xu, De-Ying Tian, Zheng-Gang Zhang, Li-Jiang Liu, Ying Chen
Pages: 829-836
Published online on: 01 March 2009

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Article

Prediction of high-risk patients by genome-wide copy number alterations from remaining cancer after neoadjuvant chemotherapy and surgery

Sun Young Rha, Hei Cheul Jeung, Min Young Seo, Sang Cheol Kim, Woo Ick Yang, Yong Wha Moon, Hyun Cheol Chung
Pages: 837-846
Published online on: 01 March 2009

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Article

Expression of prostaglandin E2 receptors in oral squamous cell carcinomas and growth inhibitory effects of an EP3 selective antagonist, ONO-AE3-240

Hiroshi Hoshikawa, Rieko Goto, Terushige Mori, Tomoo Mitani, Nozomu Mori
Pages: 847-852
Published online on: 01 March 2009

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Article

The inhibitory effect of the proinflammatory cytokine TNFα on erythroid differentiation involves erythroid transcription factor modulation

Isabelle Buck, Franck Morceau, Silvia Cristofanon, Simone Reuter, Mario Dicato, Marc Diederich
Pages: 853-860
Published online on: 01 March 2009

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Article

Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells

Pedro Miguel Lacal, Lucio Tentori, Alessia Muzi, Federica Ruffini, Annalisa Susanna Dorio, Weizheng Xu, Diego Arcelli, Jie Zhang, Grazia Graziani
Pages: 861-872
Published online on: 01 March 2009

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Selective antitumor and apoptosis‑inducing effects of the Src inhibitor PP1 in human tongue squamous cell carcinoma cells

Shirinbaeva Luiza Kantibekovna, Saini Wang, Hyunju Kang, Young-Min Shin, Byeong-Churl Jang
Article Number: 64
Published online on: 27 March 2026

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Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Article Open Access

Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Article Open Access

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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