The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)

  • Authors:
    • Bo You
    • Ying Shan
    • Lili Bao
    • Jing Chen
    • Liu Yang
    • Qicheng Zhang
    • Wei Zhang
    • Zhenxin Zhang
    • Jie Zhang
    • Si Shi
    • Yiwen You
  • View Affiliations

  • Published online on: November 10, 2017     https://doi.org/10.3892/ijo.2017.4202
  • Pages:38-46
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Abstract

Extracellular vesicles are a heterogeneous group of membrane-enclosed vesicles, which play an important role in intercellular communication. Increasing number of studies have shown that tumor-derived extracellular vesicles might be involved in the transfer of oncogenic cargo (proteins, lipids, messenger RNA, microRNA, non-coding RNAs and DNA) through which cancer cells could shape the tumor microenvironment and influence tumor progression. Nasopharyngeal carcinoma-derived extracellular vesicles have also reported to facilitate tumor proliferation, metastasis and immune escape. Moreover, nasopharyngeal carcinoma-derived extracellular vesicles might serve as biomarkers for early diagnosis and therapeutic targets. The present review provides information on the biological and clinical significance of extracellular vesicles in tumors, especially in nasopharyngeal carcinoma.

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January 2018
Volume 52 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

2016 Impact Factor: 3.079
Ranked #33/217 Oncology
(total number of cites)

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APA
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q. ... You, Y. (2018). The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review). International Journal of Oncology, 52, 38-46. https://doi.org/10.3892/ijo.2017.4202
MLA
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q., Zhang, W., Zhang, Z., Zhang, J., Shi, S., You, Y."The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)". International Journal of Oncology 52.1 (2018): 38-46.
Chicago
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q., Zhang, W., Zhang, Z., Zhang, J., Shi, S., You, Y."The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)". International Journal of Oncology 52, no. 1 (2018): 38-46. https://doi.org/10.3892/ijo.2017.4202