Non‑coding RNAs and ovarian diseases (Review)
- Authors:
- Dandan Li
- Duo Xu
- Yinggang Zou
- Ying Xu
- Lulu Fu
- Xin Xu
- Yongzheng Liu
- Xueying Zhang
- Jingshun Zhang
- Hao Ming
- Lianwen Zheng
-
Affiliations: Reproductive Medical Center, Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin 130062, P.R. China, Department of Breast Oncology, Tumor Hospital of Jilin Province, Changchun, Jilin 130021, P.R. China - Published online on: February 8, 2017 https://doi.org/10.3892/mmr.2017.6176
- Pages: 1435-1440
This article is mentioned in:
Abstract
 |
|
Lee TI and Young RA: Transcriptional regulation and its misregulation in disease. Cell. 152:1237–1251. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Lawrence MS, Stojanov P, Mermel CH, Robinson JT, Garraway LA, Golub TR, Meyerson M, Gabriel SB, Lander ES and Getz G: Discovery and saturation analysis of cancer genes across 21 tumour types. Nature. 505:495–501. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
MacLellan WR, Wang Y and Lusis AJ: Systems-based approaches to cardiovascular disease. Nat Rev Cardiol. 9:172–184. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, et al: U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci USA. 110:16562–16567. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Yang F, Yi F, Zheng Z, Ling Z, Ding J, Guo J, Mao W, Wang X, Ding X, Wang X, et al: Characterization of a carcinogenesis-associated long non-coding RNA. RNA Biol. 9:110–116. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
ENCODE Project Consortium: An integrated encyclopedia of DNA elements in the human genome. Nature. 489:57–74. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Esteller M: Non-coding RNAs in human disease. Nat Rev Genet. 12:861–874. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Flynn RA and Chang HY: Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell. 14:752–761. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Kung JT, Colognori D and Lee JT: Long noncoding RNAs: Past, present, and future. Genetics. 193:651–669. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Bachellerie JP, Cavaillé J and Hüttenhofer A: The expanding snoRNA world. Biochimie. 84:775–790. 2002. View Article : Google Scholar : PubMed/NCBI | |
|
van Stijn T and Galloway S: A BamHI polymorphism at the ovine inactive X-specific transcript locus (XIST). Anim Genet. 26:279–280. 1995. View Article : Google Scholar : PubMed/NCBI | |
|
Brockdorff N, Ashworth A, Kay GF, McCabe VM, Norris DP, Cooper PJ, Swift S and Rastan S: The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell. 71:515–526. 1992. View Article : Google Scholar : PubMed/NCBI | |
|
Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E and Chang HY: Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 129:1311–1323. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Dehwah MA, Xu A and Huang Q: MicroRNAs and type 2 diabetes/obesity. J Genet Genomics. 39:11–18. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Medina PP, Nolde M and Slack FJ: OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature. 467:86–90. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Zhao JJ, Lin J, Yang H, Kong W, He L, Ma X, Coppola D and Cheng JQ: MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem. 283:31079–31086. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Herrera-Esparza R, Kruse L, von Essen M, Campos L, Barbosa O, Bollain JJ, Badillo I and Avalos-Díaz E: U3 snoRNP associates with fibrillarin a component of the scleroderma clumpy nucleolar domain. Arch Dermatol Res. 294:310–317. 2002.PubMed/NCBI | |
|
Yang JM, Hildebromdt B, Luderschmidt C and Pollard KM: Human scleroderma sera contain autoantibodies to protein components specific to the U3 small nucleolar RNP complex. Arthritis Rheum. 48:210–217. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Nicoloso MS, Spizzo R, Shimizu M, Rossi S and Calin GA: MicroRNAs-the micro steering wheel of tumour metastases. Nature Rev Cancer. 9:293–302. 2009. View Article : Google Scholar | |
|
Sang Q, Yao Z, Wang H, Feng R, Wang H, Zhao X, Xing Q, Jin L, He L, Wu L and Wang L: Identification of microRNAs in human follicular fluid: Characterization of microRNAs that govern steroidogenesis in vitro and are associated with polycystic ovary syndrome in vivo. J Clin Endocrinol Metab. 98:3068–3079. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Yan Z, Hu HY, Jiang X, Maierhofer V, Neb E, He L, Hu Y, Hu H, Li N, Chen W and Khaitovich P: Widespread expression of piRNA-like molecules in somatic tissues. Nucleic Acids Res. 39:6596–6607. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Yang X, Zhou Y, Peng S, Wu L, Lin HY, Wang S and Wang H: Differentially expressed plasma microRNAs in premature ovarian failure patients and the potential regulatory function of mir-23a in granulosa cell apoptosis. Reproduction. 144:235–244. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Ohno S: So much ‘junk’ DNA in our genome. Brookhaven Symp Biol. 23:366–370. 1972.PubMed/NCBI | |
|
Zhang R, Zhang L and Yu W: Genome-wide expression of non-coding RNA and global chromatin modification. Acta Biochim Biophys Sin (Shanghai). 44:40–47. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Hertel J, De Jong D, Marz M, Rose D, Tafer H, Tanzer A, Schierwater B and Stadler PF: Non-coding RNA annotation of the genome of Trichoplax adhaerens. Nucleic Acids Res. 37:1602–1615. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Mohr AM and Mott JL: Overview of MicroRNA biology. Semin Liver Dis. 35:3–11. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Sirotkin AV, Lauková M, Ovcharenko D, Brenaut P and Mlyncek M: Identification of microRNAs controlling human ovarian cell proliferation and apoptosis. J Cell Physiol. 223:49–56. 2010.PubMed/NCBI | |
|
Jiang L, Huang J, Li L, Chen Y, Chen X, Zhao X and Yang D: MicroRNA-93 promotes ovarian granulosa cells proliferation through targeting CDKN1A in polycystic ovarian syndrome. J Clin Endocrinol Metab. 100:E729–E738. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Thomson T and Lin H: The biogenesis and function of PIWI proteins and piRNAs: Progress and prospect. Annu Rev Cell Dev Biol. 25:355–376. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Aravin AA, Hannon GJ and Brennecke J: The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science. 318:761–764. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Aravin AA, Sachidanandam R, Girard A, Fejes-Toth K and Hannon GJ: Developmentally regulated piRNA clusters implicate MILI in transposon control. Science. 316:744–747. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R and Hannon GJ: Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell. 128:1089–1103. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, Nagami T, Siomi H and Siomi MC: A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila. Science. 315:1587–1590. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Pal-Bhadra M, Leibovitch BA, Gandhi SG, Chikka MR, Bhadra U, Birchler JA and Elgin SC: Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science. 303:669–672. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Kiss-László Z, Henry Y, Bachellerie JP, Caizergues-Ferrer M and Kiss T: Site-specific ribose methylation of preribosomal RNA: A novel function for small nucleolar RNAs. Cell. 85:1077–1088. 1996. View Article : Google Scholar : PubMed/NCBI | |
|
Ni J, Tien AL and Fournier MJ: Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA. Cell. 89:565–573. 1997. View Article : Google Scholar : PubMed/NCBI | |
|
King TH, Liu B, McCully RR and Fournier MJ: Ribosome structure and activity are altered in cells lacking snoRNPs that form pseudouridines in the peptidyl transferase center. Mol Cell. 11:425–435. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Carthew RW and Sontheimer EJ: Origins and mechanisms of miRNAs and siRNAs. Cell. 136:642–655. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Diederichs S and Haber DA: Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell. 131:1097–1108. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Tam OH, Aravin AA, Stein P, Girard A, Murchison EP, Cheloufi S, Hodges E, Anger M, Sachidanandam R, Schultz RM and Hannon GJ: Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature. 453:534–538. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Rinn JL and Chang HY: Genome regulation by long noncoding RNAs. Annu Rev Biochem. 81:145–166. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, et al: Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 458:223–227. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, Guernec G, Martin D, Merkel A, Knowles DG, et al: The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression. Genome Res. 22:1775–1789. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Wang KC and Chang HY: Molecular mechanisms of long noncoding RNAs. Mol Cell. 43:904–914. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Brannan CI, Dees EC, Ingram RS and Tilghman SM: The product of the H19 gene may function as an RNA. Mol Cell Biol. 10:28–36. 1990. View Article : Google Scholar : PubMed/NCBI | |
|
Okamura K and Lai EC: Endogenous small interfering RNAs in animals. Nat Rev Mol Cell Biol. 9:673–678. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Ørom UA, Derrien T, Guigo R and Shiekhattar R: Long noncoding RNAs as enhancers of gene expression. Cold Spring Harb Symp Quant Biol. 75:325–331. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Feuerhahn S, Iglesias N, Panza A, Porro A and Lingner J: TERRA biogenesis, turnover and implications for function. FEBS Lett. 584:3812–3818. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Kanellopoulou C, Muljo SA, Kung AL, Ganesan S, Drapkin R, Jenuwein T, Livingston DM and Rajewsky K: Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19:489–501. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Lei L, Jin S, Gonzalez G, Behringer RR and Woodruff TK: The regulatory role of Dicer in folliculogenesis in mice. Mol Cell Endocrinol. 315:63–73. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Otsuka M, Zheng M, Hayashi M, Lee JD, Yoshino O, Lin S and Han J: Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice. J Clin Invest. 118:1944–1954. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Hossain MM, Cao M, Wang Q, Kim JY, Schellander K, Tesfaye D and Tsang BK: Altered expression of miRNAs in a dihydrotestosterone-induced rat PCOS model. J Ovarian Res. 6:362013. View Article : Google Scholar : PubMed/NCBI | |
|
Malone CD, Brennecke J, Dus M, Stark A, McCombie WR, Sachidanandam R and Hannon GJ: Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell. 137:522–535. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Li C, Vagin VV, Lee S, Xu J, Ma S, Xi H, Seitz H, Horwich MD, Syrzycka M, Honda BM, et al: Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell. 137:509–521. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Saito K, Inagaki S, Mituyama T, Kawamura Y, Ono Y, Sakota E, Kotani H, Asai K, Siomi H and Siomi MC: A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila. Nature. 461:1296–1299. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Sasaki H and Matsui Y: Epigenetic events in mammalian germ-cell development: Reprogramming and beyond. Nat Rev Genet. 9:129–140. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Esquela-Kerscher A and Slack FJ: OncomiRs-microRNAs with a role in cancer. Nat Rev Cancer. 6:259–269. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
Hammond SM: MicroRNAs as tumor suppressors. Nat Genet. 39:582–583. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Croce CM: Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet. 10:704–714. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S, Shimizu M, Rattan S, Bullrich F, Negrini M and Croce CM: Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA. 101:2999–3004. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ and O'Malley BW: A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 97:17–27. 1999. View Article : Google Scholar : PubMed/NCBI | |
|
Cooper C, Guo J, Yan Y, Chooniedass-Kothari S, Hube F, Hamedani MK, Murphy LC, Myal Y and Leygue E: Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides. Nucleic Acids Res. 37:4518–4531. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Lanz RB, Chua SS, Barron N, Söder BM, DeMayo F and O'Malley BW: Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo. Mol Cell Biol. 23:7163–7176. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Miura K, Obama M, Yun K, Masuzaki H, Ikeda Y, Yoshimura S, Akashi T, Niikawa N, Ishimaru T and Jinno Y: Methylation imprinting of H19 and SNRPN genes in human benign ovarian teratomas. Am J Hum Genet. 65:1359–1367. 1999. View Article : Google Scholar : PubMed/NCBI | |
|
Yang F, Yi F, Zheng Z, Ling Z, Ding J, Guo J, Mao W, Wang X, Wang X, Ding X, et al: Characterization of a carcinogenesis-associated long non-coding RNA. RNA Biol. 9:110–116. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Lee JH, Schütte D, Wulf G, Füzesi L, Radzun HJ, Schweyer S, Engel W and Nayernia K: Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3/Bcl-XL pathway. Hum Mol Genet. 15:201–211. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
Chang LS, Lin SY, Lieu AS and Wu TL: Differential expression of human 5S snoRNA genes. Biochem Biophys Res Commun. 299:196–200. 2002. View Article : Google Scholar : PubMed/NCBI | |
|
Liao J, Yu L, Mei Y, Guarnera M, Shen J, Li R, Liu Z and Jiang F: Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer. Mol Cancer. 9:1982010. View Article : Google Scholar : PubMed/NCBI | |
|
Dong XY, Guo P, Boyd J, Sun X, Li Q, Zhou W and Dong JT: Implication of snoRNA U50 in human breast cancer. J Genet Genomics. 36:447–454. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Roth LW, McCallie B, Alvero R, Schoolcraft WB, Minjarez D and Katz-Jaffe MG: Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome. J Assist Reprod Genet. 31:355–362. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Liu S, Zhang X, Shi C, Lin J, Chen G, Wu B, Wu L, Shi H, Yuan Y, Zhou W, et al: Altered microRNAs expression profiling in cumulus cells from patients with polycystic ovary syndrome. J Transl Med. 13:2382015. View Article : Google Scholar : PubMed/NCBI | |
|
Lin L, Du T, Huang J, Huang LL and Yang DZ: Identification of differentially expressed microRNAs in the ovary of polycystic ovary syndrome with hyperandrogenism and insulin resistance. Chin Med J (Enql). 128:169–174. 2015. View Article : Google Scholar | |
|
Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery CA Jr, Shyamala G, Conneely OM and O'Malley BW: Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 9:2266–2278. 1995. View Article : Google Scholar : PubMed/NCBI | |
|
Zurvarra FM, Salvetti NR, Mason JI, Velazquez MM, Alfaro NS and Ortega HH: Disruption in the expression and immunolocalisation of steroid receptors and steroidogenic enzymes in letrozole-induced polycystic ovaries in rat. Reprod Fertil Dev. 21:827–839. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Zhao X, Patton JR, Davis SL, Florence B, Ames SJ and Spanjaard RA: Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator. Mol Cell. 15:549–558. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Takayama K, Tsutsumi S, Katayama S, Okayama T, Horie-Inoue K, Ikeda K, Urano T, Kawazu C, Hasegawa A, Ikeo K, et al: Integration of cap analysis of gene expression and chromatin immunoprecipitation analysis on array reveals genome-wide androgen receptor signaling in prostate cancer cells. Oncogene. 30:619–630. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Kuang H, Han D, Xie J, Yan Y, Li J and Ge P: Profiling of differentially expressed microRNAs in premature ovarian failure in an animal model. Gynecol Endocrinol. 30:57–61. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, Guo J, Zhang Y, Chen J, Guo X, et al: Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 18:997–1006. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Long W, Zhao C, Ji C, Ding H, Cui Y, Guo X, Shen R and Liu J: Characterization of serum microRNAs profile of PCOS and identification of novel non-invasive biomarkers. Cell Physiol Biochem. 33:1304–1315. 2014. View Article : Google Scholar : PubMed/NCBI |
