18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor

  • Authors:
    • Sied Kebir
    • Okka Kimmich
    • Pitt Niehusmann
    • Florian C. Gaertner
    • Markus Essler
    • Jennifer Landsberg
    • Thomas Klockgether
    • Matthias Simon
    • Ulrich Herrlinger
    • Martin Glas
  • View Affiliations

  • Published online on: October 10, 2016     https://doi.org/10.3892/ol.2016.5234
  • Pages: 4705-4707
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Abstract

Diagnosis in patients with a suspected malignant intramedullary lesion that requires biopsy for definitive diagnosis may be challenging, as spinal cord surgery carries the risk of irreversible neurological deficits. The current study presents the first case of 18F-fluoroethyl-L-tyrosine (18F-FET) positron emission tomography (PET) imaging in a patient with a spinal cord tumor. The patient was unsuitable for magnetic resonance imaging due to his implanted cardiac defibrillator. 18F‑FET PET indicated a high‑grade malignancy of the spinal cord, justifying tumor biopsy. Histological analysis was compatible with a malignant melanoma. This is also the first report demonstrating the FET‑PET appearance/metabolic phenotype of a malignant melanoma of the spinal cord.
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December-2016
Volume 12 Issue 6

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Kebir S, Kimmich O, Niehusmann P, Gaertner FC, Essler M, Landsberg J, Klockgether T, Simon M, Herrlinger U, Glas M, Glas M, et al: 18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor. Oncol Lett 12: 4705-4707, 2016
APA
Kebir, S., Kimmich, O., Niehusmann, P., Gaertner, F.C., Essler, M., Landsberg, J. ... Glas, M. (2016). 18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor. Oncology Letters, 12, 4705-4707. https://doi.org/10.3892/ol.2016.5234
MLA
Kebir, S., Kimmich, O., Niehusmann, P., Gaertner, F. C., Essler, M., Landsberg, J., Klockgether, T., Simon, M., Herrlinger, U., Glas, M."18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor". Oncology Letters 12.6 (2016): 4705-4707.
Chicago
Kebir, S., Kimmich, O., Niehusmann, P., Gaertner, F. C., Essler, M., Landsberg, J., Klockgether, T., Simon, M., Herrlinger, U., Glas, M."18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor". Oncology Letters 12, no. 6 (2016): 4705-4707. https://doi.org/10.3892/ol.2016.5234