1
|
Zhang YW, Shi J, Li YJ and Wei L:
Cardiomyocyte death in doxorubicin-induced cardiotoxicity. Arch
Immunol Ther Exp (Warsz). 57:435–445. 2009. View Article : Google Scholar : PubMed/NCBI
|
2
|
Octavia Y, Tocchetti CG, Gabrielson KL,
Janssens S, Crijns HJ and Moens AL: Doxorubicin-induced
cardiomyopathy: from molecular mechanisms to therapeutic
strategies. J Mol Cell Cardiol. 52:1213–1225. 2012. View Article : Google Scholar : PubMed/NCBI
|
3
|
Simůnek T, Stérba M, Popelová O, Adamcová
M, Hrdina R and Gersl V: Anthracycline-induced cardiotoxicity:
Overview of studies examining the roles of oxidative stress and
free cellular iron. Pharmacol Rep. 61:154–171. 2009. View Article : Google Scholar : PubMed/NCBI
|
4
|
Kumar D, Kirshenbaum LA, Li T, Danelisen I
and Singal PK: Apoptosis in adriamycin cardiomyopathy and its
modulation by probucol. Antioxid Redox Signal. 3:135–145. 2001.
View Article : Google Scholar : PubMed/NCBI
|
5
|
Kobayashi S, Volden P, Timm D, Mao K, Xu X
and Liang Q: Transcription factor GATA4 inhibits
doxorubicin-induced au-tophagy and cardiomyocyte death. J Biol
Chem. 285:793–804. 2010. View Article : Google Scholar : PubMed/NCBI
|
6
|
Nitobe J, Yamaguchi S, Okuyama M, Nozaki
N, Sata M, Miyamoto T, Takeishi Y, Kubota I and Tomoike H: Reactive
oxygen species regulate FLICE inhibitory protein (FLIP) and
susceptibility to Fas-mediated apoptosis in cardiac myocytes.
Cardiovasc Res. 57:119–128. 2003. View Article : Google Scholar : PubMed/NCBI
|
7
|
Grethe S, Coltella N, Di Renzo MF and
Pörn-Ares MI: p38 MAPK downregulates phosphorylation of Bad in
doxorubicin-induced endothelial apoptosis. Biochem Biophys Res
Commun. 347:781–790. 2006. View Article : Google Scholar : PubMed/NCBI
|
8
|
Arai M, Yoguchi A, Takizawa T, Yokoyama T,
Kanda T, Kurabayashi M and Nagai R: Mechanism of
doxorubicin-induced inhibition of sarcoplasmic reticulum
Ca(2+)-ATPase gene transcription. Circ Res. 86:8–14. 2000.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Yang B, Ye D and Wang Y: Caspase-3 as a
therapeutic target for heart failure. Expert Opin Ther Targets.
17:255–263. 2013. View Article : Google Scholar : PubMed/NCBI
|
10
|
Dirks-Naylor AJ: The role of autophagy in
doxorubicin-induced cardiotoxicity. Life Sci. 93:913–916. 2013.
View Article : Google Scholar : PubMed/NCBI
|
11
|
Sciarretta S, Hariharan N, Monden Y,
Zablocki D and Sadoshima J: Is autophagy in response to ischemia
and reperfusion protective or detrimental for the heart? Pediatr
Cardiol. 32:275–281. 2011. View Article : Google Scholar : PubMed/NCBI
|
12
|
Chen K, Xu X, Kobayashi S, Timm D,
Jepperson T and Liang Q: Caloric restriction mimetic 2-deoxyglucose
antagonizes doxorubicin-induced cardiomyocyte death by multiple
mechanisms. J Biol Chem. 286:21993–22006. 2011. View Article : Google Scholar : PubMed/NCBI
|
13
|
Xu X, Chen K, Kobayashi S, Timm D and
Liang Q: Resveratrol attenuates doxorubicin-induced cardiomyocyte
death via inhibition of p70 S6 kinase 1-mediated autophagy. J
Pharmacol Exp Ther. 341:183–195. 2012. View Article : Google Scholar : PubMed/NCBI
|
14
|
Gottlieb RA and Mentzer RM Jr:
Cardioprotection through autophagy: Ready for clinical trial?
Autophagy. 7:434–435. 2011. View Article : Google Scholar : PubMed/NCBI
|
15
|
Zhu H, Tannous P, Johnstone JL, Kong Y,
Shelton JM, Richardson JA, Le V, Levine B, Rothermel BA and Hill
JA: Cardiac autophagy is a maladaptive response to hemodynamic
stress. J Clin Invest. 117:1782–1793. 2007. View Article : Google Scholar : PubMed/NCBI
|
16
|
Hein S, Arnon E, Kostin S, Schönburg M,
Elsässer A, Polyakova V, Bauer EP, Klövekorn WP and Schaper J:
Progression from compensated hypertrophy to failure in the
pressure-overloaded human heart: Structural deterioration and
compensatory mechanisms. Circulation. 107:984–991. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Kostin S, Pool L, Elsässer A, Hein S,
Drexler HC, Arnon E, Hayakawa Y, Zimmermann R, Bauer E, Klövekorn
WP and Schaper J: Myocytes die by multiple mechanisms in failing
human hearts. Circ Res. 92:715–724. 2003. View Article : Google Scholar : PubMed/NCBI
|
18
|
Chen HH, Mekkaoui C, Cho H, Ngoy S,
Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L and
Sosnovik DE: Fluorescence tomography of rapamycin-induced autophagy
and cardioprotection in vivo. Circ Cardiovasc Imaging. 6:441–447.
2013. View Article : Google Scholar : PubMed/NCBI
|
19
|
Huang C, Yitzhaki S, Perry CN, Liu W,
Giricz Z, Mentzer RM Jr and Gottlieb RA: Autophagy induced by
ischemic preconditioning is essential for cardioprotection. J
Cardiovasc Transl Res. 3:365–373. 2010. View Article : Google Scholar : PubMed/NCBI
|
20
|
Haar L, Ren X, Liu Y, Koch SE, Goines J,
Tranter M, Engevik MA, Nieman M, Rubinstein J and Jones WK: Acute
consumption of a high-fat diet prior to ischemia-reperfusion
results in cardioprotection through NF-κB-dependent regulation of
autophagic pathways. Am J Physiol Heart Circ Physiol.
307:H1705–H1713. 2014. View Article : Google Scholar : PubMed/NCBI
|
21
|
Matsui Y, Takagi H, Qu X, Abdellatif M,
Sakoda H, Asano T, Levine B and Sadoshima J: Distinct roles of
autophagy in the heart during ischemia and reperfusion: Roles of
AMP-activated protein kinase and Beclin 1 in mediating autophagy.
Circ Res. 100:914–922. 2007. View Article : Google Scholar : PubMed/NCBI
|
22
|
Matsunaga K, Saitoh T, Tabata K, Omori H,
Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe
T, et al: Two Beclin 1-binding proteins, Atg14L and Rubicon,
reciprocally regulate autophagy at different stages. Nat Cell Biol.
11:385–396. 2009. View
Article : Google Scholar : PubMed/NCBI
|
23
|
Zhong Y, Wang QJ and Yue Z: Atg14L and
Rubicon: yin and yang of Beclin 1-mediated autophagy control.
Autophagy. 5:890–891. 2009. View Article : Google Scholar : PubMed/NCBI
|
24
|
Zhong Y, Wang QJ, Li X, Yan Y, Backer JM,
Chait BT, Heintz N and Yue Z: Distinct regulation of autophagic
activity by Atg14L and Rubicon associated with Beclin
1-phosphatidylinositol-3-kinase complex. Nat Cell Biol. 11:468–476.
2009. View
Article : Google Scholar : PubMed/NCBI
|
25
|
Kimura S, Fujita N, Noda T and Yoshimori
T: Monitoring autophagy in mammalian cultured cells through the
dynamics of LC3. Methods Enzymol. 452:1–12. 2009. View Article : Google Scholar : PubMed/NCBI
|
26
|
Liang C, Lee JS, Inn KS, Gack MU, Li Q,
Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C and Jung JU:
Beclin1-binding UVRAG targets the class C Vps complex to coordinate
autophagosome maturation and endocytic trafficking. Nat Cell Biol.
10:776–787. 2008. View
Article : Google Scholar : PubMed/NCBI
|
27
|
BenYounès A, Tajeddine N, Tailler M, Malik
SA, Shen S, Métivier D, Kepp O, Vitale I, Maiuri MC and Kroemer G:
A fluorescence-microscopic and cytofluorometric system for
monitoring the turnover of the autophagic substrate p62/SQSTM1.
Autophagy. 7:883–891. 2011. View Article : Google Scholar : PubMed/NCBI
|
28
|
Levine B and Yuan J: Autophagy in cell
death: An innocent convict? J Clin Invest. 115:2679–2688. 2005.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Rubinstein AD and Kimchi A: Life in the
balance-a mechanistic view of the crosstalk between autophagy and
apoptosis. J Cell Sci. 125:5259–5268. 2012. View Article : Google Scholar : PubMed/NCBI
|
30
|
Pyo JO, Jang MH, Kwon YK, Lee HJ, Jun JI,
Woo HN, Cho DH, Choi B, Lee H, Kim JH, et al: Essential roles of
Atg5 and FADD in autophagic cell death: Dissection of autophagic
Cell death into vacuole formation and cell death. J Biol Chem.
280:20722–20729. 2005. View Article : Google Scholar : PubMed/NCBI
|
31
|
Yousefi S, Perozzo R, Schmid I, Ziemiecki
A, Schaffner T, Scapozza L, Brunner T and Simon HU:
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.
Nat Cell Biol. 8:1124–1132. 2006. View
Article : Google Scholar : PubMed/NCBI
|
32
|
Zhou F, Yang Y and Xing D: Bcl-2 and
Bcl-xL play important roles in the crosstalk between autophagy and
apoptosis. FEBS J. 278:403–413. 2011. View Article : Google Scholar : PubMed/NCBI
|
33
|
Aries A, Paradis P, Lefebvre C, Schwartz
RJ and Nemer M: Essential role of GATA-4 in cell survival and
drug-induced cardiotoxicity. Proc Natl Acad Sci USA. 101:pp.
6975–6980. 2004; View Article : Google Scholar : PubMed/NCBI
|
34
|
Eisenberg-Lerner A, Bialik S, Simon HU and
Kimchi A: Life and death partners: Apoptosis, autophagy and the
cross-talk between them. Cell Death Differ. 16:966–975. 2009.
View Article : Google Scholar : PubMed/NCBI
|
35
|
Li K, Sung RY, Huang WZ, Yang M, Pong NH,
Lee SM, Chan WY, Zhao H, To MY, Fok TF, et al: Thrombopoietin
protects against in vitro and in vivo cardiotoxicity induced by
doxorubicin. Circulation. 113:2211–2220. 2006. View Article : Google Scholar : PubMed/NCBI
|
36
|
Kuter DJ and Begley CG: Recombinant human
thrombopoietin: Basic biology and evaluation of clinical studies.
Blood. 100:3457–3469. 2002. View Article : Google Scholar : PubMed/NCBI
|
37
|
Majka M, Ratajczak J, Villaire G, Kubiczek
K, Marquez LA, Janowska-Wieczorek A and Ratajczak MZ:
Thrombopoietin, but not cytokines binding to gp130 protein-coupled
receptors, activates MAPKp42/44, AKT, and STAT proteins in normal
human CD34+ cells, megakaryocytes, and platelets. Exp Hematol.
30:751–760. 2002. View Article : Google Scholar : PubMed/NCBI
|
38
|
Chan KY, Xiang P, Zhou L, Li K, Ng PC,
Wang CC, Zhang L, Deng HY, Pong NH, Zhao H, et al: Thrombopoietin
protects against doxorubicin-induced cardiomyopathy, improves
cardiac function, and reversely alters specific signalling
networks. Eur J Heart Fail. 13:366–376. 2011. View Article : Google Scholar : PubMed/NCBI
|
39
|
Baker JE, Su J, Hsu A, Shi Y, Zhao M,
Strande JL, Fu X, Xu H, Eis A, Komorowski R, et al: Human
thrombopoietin reduces myocardial infarct size, apoptosis, and
stunning following ischaemia/reperfusion in rats. Cardiovasc Res.
77:44–53. 2008. View Article : Google Scholar : PubMed/NCBI
|
40
|
Yu Y, Shiou SR, Guo Y, Lu L, Westerhoff M,
Sun J, Petrof EO and Claud EC: Erythropoietin protects epithelial
cells from excessive autophagy and apoptosis in experimental
neonatal necrotizing enterocolitis. PLoS One. 8:e696202013.
View Article : Google Scholar : PubMed/NCBI
|
41
|
de Sauvage FJ, Hass PE, Spencer SD, Malloy
BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang
WJ, et al: Stimulation of megakaryocytopoiesis and thrombopoiesis
by the c-Mpl ligand. Nature. 369:533–538. 1994. View Article : Google Scholar : PubMed/NCBI
|
42
|
Tramontano AF, Muniyappa R, Black AD,
Blendea MC, Cohen I, Deng L, Sowers JR, Cutaia MV and El-Sherif N:
Erythropoietin protects cardiac myocytes from hypoxia-induced
apoptosis through an Akt-dependent pathway. Biochem Biophys Res
Commun. 308:990–994. 2003. View Article : Google Scholar : PubMed/NCBI
|
43
|
Parsa CJ, Matsumoto A, Kim J, Riel RU,
Pascal LS, Walton GB, Thompson RB, Petrofski JA, Annex BH, Stamler
JS and Koch WJ: A novel protective effect of erythropoietin in the
infarcted heart. J Clin Invest. 112:999–1007. 2003. View Article : Google Scholar : PubMed/NCBI
|
44
|
Peter AK, Bjerke MA and Leinwand LA:
Biology of the cardiac myocyte in heart disease. Mol Biol Cell.
27:2149–2160. 2016. View Article : Google Scholar : PubMed/NCBI
|
45
|
Yoshimori T, Yamamoto A, Moriyama Y, Futai
M and Tashiro Y: Bafilomycin A1, a specific inhibitor of
vacuolar-type H(+)-ATPase, inhibits acidification and protein
degradation in lysosomes of cultured cells. J Biol Chem.
266:17707–17712. 1991.PubMed/NCBI
|
46
|
Hescheler J, Meyer R, Plant S, Krautwurst
D, Rosenthal W and Schultz G: Morphological, biochemical, and
electrophysiological characterization of a clonal cell (H9c2) line
from rat heart. Circ Res. 69:1476–1486. 1991. View Article : Google Scholar : PubMed/NCBI
|
47
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
48
|
Hannan NR, Jamshidi P, Pera MF and
Wolvetang EJ: BMP-11 and myostatin support undifferentiated growth
of human embryonic stem cells in feeder-free cultures. Cloning Stem
Cells. 11:427–435. 2009. View Article : Google Scholar : PubMed/NCBI
|
49
|
Zhang YY, Meng C, Zhang XM, Yuan CH, Wen
MD, Chen Z, Dong DC, Gao YH, Liu C and Zhang Z: Ophiopogonin D
attenuates doxorubicin-induced autophagic cell death by relieving
mitochondrial damage in vitro and in vivo. J Pharmacol Exp Ther.
352:166–174. 2015. View Article : Google Scholar : PubMed/NCBI
|
50
|
Eskelinen EL: Roles of LAMP-1 and LAMP-2
in lysosome biogenesis and autophagy. Mol Aspects Med. 27:495–502.
2006. View Article : Google Scholar : PubMed/NCBI
|
51
|
Sishi BJ, Loos B, van Rooyen J and
Engelbrecht AM: Autophagy upregulation promotes survival and
attenuates doxorubicin-induced cardiotoxicity. Biochem Pharmacol.
85:124–134. 2013. View Article : Google Scholar : PubMed/NCBI
|