Open Access

Association between long non-coding RNAs expression and pathogenesis and progression of gliomas (Review)

  • Authors:
    • Jie Zhou
    • Wei Xiang
    • Shenjie Li
    • Qi Hu
    • Tao Peng
    • Ligang Chen
    • Yang Ming
  • View Affiliations

  • Published online on: January 26, 2018     https://doi.org/10.3892/ol.2018.7875
  • Pages:4070-4078
  • Copyright: © Zhou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The incidence rate of gliomas is the highest among primary brain tumors. Although the understanding of the molecular pathology of glioma has improved during the previous two decades, effective therapies are not yet available to treat these tumors. Previous studies have indicated that long non‑coding RNAs (lncRNAs) have a close association with glioma, suggesting that lncRNAs may be potential targets for the development of novel treatments for glioma. The present review summarized the latest studies on the dysregulation of lncRNAs in glioma, and discussed their potential use in the diagnosis, prognosis and therapies of glioma. The emergence of lncRNAs has revealed an additional facet to glioma oncogenesis. An improved understanding of their functions is important to advance lncRNA‑based diagnosis, prognosis and therapeutic interventions of glioma.

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Journal Cover

April 2018
Volume 15 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

2016 Impact Factor: 1.39
Ranked #68/217 Oncology
(total number of cites)

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APA
Zhou, J., Xiang, W., Li, S., Hu, Q., Peng, T., Chen, L., & Ming, Y. (2018). Association between long non-coding RNAs expression and pathogenesis and progression of gliomas (Review). Oncology Letters, 15, 4070-4078. https://doi.org/10.3892/ol.2018.7875
MLA
Zhou, J., Xiang, W., Li, S., Hu, Q., Peng, T., Chen, L., Ming, Y."Association between long non-coding RNAs expression and pathogenesis and progression of gliomas (Review)". Oncology Letters 15.4 (2018): 4070-4078.
Chicago
Zhou, J., Xiang, W., Li, S., Hu, Q., Peng, T., Chen, L., Ming, Y."Association between long non-coding RNAs expression and pathogenesis and progression of gliomas (Review)". Oncology Letters 15, no. 4 (2018): 4070-4078. https://doi.org/10.3892/ol.2018.7875