Open Access

Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography

  • Authors:
    • Rui Fang
    • Yong Yang
    • Haicheng Han
    • Xiaoqing Fu
    • Liwen Dong
    • Baisheng Xie
    • Wei Lu
    • Chenyang Ma
    • Feng Cui
    • Jian Hu
    • Jun Wang
  • View Affiliations

  • Published online on: June 6, 2018     https://doi.org/10.3892/ol.2018.8921
  • Pages: 2483-2489
  • Copyright: © Fang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Risk factors for stage I lung adenocarcinoma were analyzed using low‑dose high‑resolution computed tomography (CT). The patients were divided into case group (stage I lung adenocarcinoma patients) and control group (benign pulmonary nodules patients). All patients were subjected to low‑dose high‑resolution CT. Multiple linear regression was performed to analyze the CT imaging features of the two groups. Stage I lung adenocarcinoma patients were significantly associated with nodular site (X3, upper left lobe) [95% CI (1.796, 54.695), p=0.008], nodule type (X4) (p<0.001), nodule size (X5) [95% CI (0.614, 0.803), p<0.001], spicule sign (X7) [95% CI (0.029, 0.580), p=0.008], lobulation sign (X8) [95% CI (0.048, 0.673), p=0.011]. The stepwise regression equation is: Logistic (p) = ‑12.009 + 2.294X3 ‑ 0.327X4 ‑ 0.354X5 ‑ 2.042X7 ‑ 1.713X8. Risk factors of low‑dose and high‑resolution CT imaging for patients with stage I lung adenocarcinoma are nodular site (upper left lobe), nodule type, nodule size, spicule sign, and lobulation sign.
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August-2018
Volume 16 Issue 2

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Spandidos Publications style
Fang R, Yang Y, Han H, Fu X, Dong L, Xie B, Lu W, Ma C, Cui F, Hu J, Hu J, et al: Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography. Oncol Lett 16: 2483-2489, 2018
APA
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B. ... Wang, J. (2018). Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography. Oncology Letters, 16, 2483-2489. https://doi.org/10.3892/ol.2018.8921
MLA
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B., Lu, W., Ma, C., Cui, F., Hu, J., Wang, J."Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography". Oncology Letters 16.2 (2018): 2483-2489.
Chicago
Fang, R., Yang, Y., Han, H., Fu, X., Dong, L., Xie, B., Lu, W., Ma, C., Cui, F., Hu, J., Wang, J."Analysis of risk factors for stage I lung adenocarcinoma using low‑dose high‑resolution computed tomography". Oncology Letters 16, no. 2 (2018): 2483-2489. https://doi.org/10.3892/ol.2018.8921