1
|
Siegel R, Naishadham D and Jemal A: Cancer
statistics, 2012. Ca Cancer J Clin. 62:10–29. 2012. View Article : Google Scholar : PubMed/NCBI
|
2
|
Schneider M, Huber J, Hadaschik B, Siegers
GM, Fiebig HH and Schüler J: Characterization of colon cancer
cells: A functional approach characterizing CD133 as a potential
stem cell marker. BMC Cancer. 12:962012. View Article : Google Scholar : PubMed/NCBI
|
3
|
Asfaha S, Hayakawa Y, Muley A, Stokes S,
Graham TA, Ericksen RE, Westphalen CB, von Burstin J, Mastracci TL,
Worthley DL, et al: Krt19(+)/Lgr5(−) cells are radioresistant
cancer-initiating stem cells in the colon and intestine. Cell Stem
Cell. 16:627–638. 2015. View Article : Google Scholar : PubMed/NCBI
|
4
|
Pang R, Law WL, Chu AC, Poon JT, Lam CS,
Chow AK, Ng L, Cheung LW, Lan XR, Lan HY, et al: A subpopulation of
CD26+ cancer stem cells with metastatic capacity in human
colorectal cancer. Cell Stem Cell. 6:6032010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Pattabiraman DR and Weinberg RA: Tackling
the cancer stem cells-what challenges do they pose? Nat Rev Drug
Discov. 13:497–512. 2014. View
Article : Google Scholar : PubMed/NCBI
|
6
|
Varnat F, Siegl-Cachedenier I, Malerba M,
Gervaz P and Ruiz i Altaba A: Loss of WNT-TCF addiction and
enhancement of HH-GLI1 signalling define the metastatic transition
of human colon carcinomas. EMBO Mol Med. 2:440–457. 2010.
View Article : Google Scholar : PubMed/NCBI
|
7
|
Bao B, Wang Z, Ali S, Kong D, Li Y, Ahmad
A, Banerjee S, Azmi AS, Miele L and Sarkar FH: Notch-1 induces
epithelial-mesenchymal transition consistent with cancer stem cell
phenotype in pancreatic cancer cells. Cancer Lett. 307:26–36. 2011.
View Article : Google Scholar : PubMed/NCBI
|
8
|
Zhao C, Chen A, Jamieson CH, Fereshteh M,
Abrahamsson A, Blum J, Kwon HY, Kim J, Chute JP, Rizzieri D, et al:
Hedgehog signalling is essential for maintenance of cancer stem
cells in myeloid leukaemia. Nature. 458:776–779. 2009. View Article : Google Scholar : PubMed/NCBI
|
9
|
Vermeulen L, De Sousa E, Melo F, van der
Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M,
Merz C, Rodermond H, et al: Wnt activity defines colon cancer stem
cells and is regulated by the microenvironment. Nat Cell Biol.
12:468–476. 2015. View
Article : Google Scholar
|
10
|
Takebe N, Miele L, Harris PJ, Jeong W,
Bando H, Kahn M, Yang SX and Ivy SP: Targeting Notch, Hedgehog, and
Wnt pathways in cancer stem cells: Clinical update. Nat Rev Clin
Oncol. 12:445–464. 2015. View Article : Google Scholar : PubMed/NCBI
|
11
|
Takebe N, Harris PJ, Warren RQ and Ivy SP:
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog
pathways. Nat Rev Clin Oncol. 8:97–106. 2011. View Article : Google Scholar : PubMed/NCBI
|
12
|
He J, Sheng T, Stelter AA, Li C, Zhang X,
Sinha M, Luxon BA and Xie J: Suppressing Wnt signaling by the
hedgehog pathway through sFRP-1. J Biol Chem. 281:35598–35602.
2006. View Article : Google Scholar : PubMed/NCBI
|
13
|
Clark-Langone KM, Sangli C, Krishnakumar J
and Watson D: Translating tumor biology into personalized treatment
planning: Analytical performance characteristics of the Oncotype DX
colon cancer assay. BMC Cancer. 10:6912010. View Article : Google Scholar : PubMed/NCBI
|
14
|
Gray RG, Quirke P, Handley K, Lopatin M,
Magill L, Baehner FL, Beaumont C, Clark-Langone KM, Yoshizawa CN,
Lee M, et al: Validation study of a quantitative multigene reverse
transcriptase-polymerase chain reaction assay for assessment of
recurrence risk in patients with stage II colon cancer. J Clin
Oncol. 29:4611–4619. 2011. View Article : Google Scholar : PubMed/NCBI
|
15
|
Salazar R, Roepman P, Capella G, Moreno V,
Simon I, Dreezen C, Lopez-Doriga A, Santos C, Marijnen C, Westerga
J, et al: Gene expression signature to improve prognosis prediction
of stage II and III colorectal cancer. J Clin Oncol. 29:17–24.
2011. View Article : Google Scholar : PubMed/NCBI
|
16
|
Agesen TH, Sveen A, Merok MA, Lind GE,
Nesbakken A, Skotheim RI and Lothe RA: ColoGuideEx: A robust gene
classifier specific for stage II colorectal cancer prognosis. Gut.
61:1560–1567. 2012. View Article : Google Scholar : PubMed/NCBI
|
17
|
Cline MS, Craft B, Swatloski T, Goldman M,
Ma S, Haussler D and Zhu J: Exploring TCGA pan-cancer data at the
UCSC cancer genomics browser. Sci Rep. 3:26522013. View Article : Google Scholar : PubMed/NCBI
|
18
|
Lu X, Wan F, Zhang H, Shi G and Ye D:
ITGA2B and ITGA8 are predictive of prognosis in clear cell renal
cell carcinoma patients. Tumor Biol. 37:253–262. 2016. View Article : Google Scholar
|
19
|
Marisa L, Reyniès AD, Duval A, Selves J,
Gaub MP, Vescovo L, Etienne-Grimaldi MC, Schiappa R, Guenot D,
Ayadi M, et al: Gene expression classification of colon cancer into
molecular subtypes: Characterization, validation, and prognostic
value. PLoS Med. 10:e10014532013. View Article : Google Scholar : PubMed/NCBI
|
20
|
Smith JJ, Deane NG, Wu F, Merchant NB,
Zhang B, Jiang A, Lu P, Johnson JC, Schmidt C, Bailey CE, et al:
Experimentally derived metastasis gene expression profile predicts
recurrence and death in patients with colon cancer.
Gastroenterology. 138:958–968. 2010. View Article : Google Scholar : PubMed/NCBI
|
21
|
Freeman TJ, Smith JJ, Chen X, Washington
MK, Roland JT, Means AL, Eschrich SA, Yeatman TJ, Deane NG and
Beauchamp RD: Smad4-mediated signaling inhibits intestinal
neoplasia by inhibiting expression of β-catenin. Gastroenterology.
142:562–571.e2. 2012. View Article : Google Scholar : PubMed/NCBI
|
22
|
Luo T, Dunphy PS, Lina TT and McBride JW:
Ehrlichia chaffeensis exploits canonical and noncanonical host wnt
signaling pathways to stimulate phagocytosis and promote
intracellular survival. Infect Immun. 84:686–700. 2015. View Article : Google Scholar : PubMed/NCBI
|
23
|
Simon R, Lam A, Li MC, Ngan M, Menenzes S
and Zhao Y: Analysis of gene expression data using BRB-ArrayTools.
Cancer Inform. 3:11–17. 2007. View Article : Google Scholar : PubMed/NCBI
|
24
|
Kawaguchi A, Iwadate Y, Komohara Y, Sano
M, Kajiwara K, Yajima N, Tsuchiya N, Homma J, Aoki H, Kobayashi T,
et al: Gene expression signature-based prognostic risk score in
patients with primary central nervous system lymphoma. Clin Cancer
Res. 18:5672–5681. 2012. View Article : Google Scholar : PubMed/NCBI
|
25
|
Zhang XQ, Sun S, Lam KF, Kiang KM, Pu JK,
Ho AS, Lui WM, Fung CF, Wong TS and Leung GK: A long non-coding RNA
signature in glioblastoma multiforme predicts survival. Neurobiol
Dis. 58:123–131. 2013. View Article : Google Scholar : PubMed/NCBI
|
26
|
Jin M, Li P, Zhang Q, Yang Z and Fu S: A
four-long non-coding RNA signature in predicting breast cancer
survival. J Exp Clin Cancer Res. 33:842014. View Article : Google Scholar : PubMed/NCBI
|
27
|
Lan YT, Yang SH, Chang SC, Liang WY, Li
AF, Wang HS, Jiang JK, Chen WS, Lin TC and Lin JK: Analysis of the
seventh edition of American joint committee on colon cancer
staging. Int J Colorectal Dis. 27:657–663. 2012. View Article : Google Scholar : PubMed/NCBI
|
28
|
Keyomarsi K, Tucker SL, Buchholz TA,
Callister M, Ding Y, Hortobagyi GN, Bedrosian I, Knickerbocker C,
Toyofuku W, Lowe M, et al: Cyclin E and survival in patients with
breast cancer. N Engl J Med. 347:1566–1575. 2002. View Article : Google Scholar : PubMed/NCBI
|
29
|
Pils D, Bachmayr-Heyda A, Auer K, Svoboda
M, Auner V, Hager G, Obermayr E, Reiner A, Reinthaller A, Speiser
P, et al: Cyclin E1 (CCNE1) as independent positive prognostic
factor in advanced stage serous ovarian cancer patients-a study of
the OVCAD consortium. Eur J Cancer. 50:99–110. 2014. View Article : Google Scholar : PubMed/NCBI
|
30
|
Christ A, Christa A, Kur E, Lioubinski O,
Bachmann S, Willnow TE and Hammes A: LRP2 is an auxiliary SHH
receptor required to condition the forebrain ventral midline for
inductive signals. Dev Cell. 22:268–278. 2012. View Article : Google Scholar : PubMed/NCBI
|
31
|
Andersen RK, Hammer K, Hager H,
Christensen JN, Ludvigsen M, Honoré B, Thomsen MB and Madsen M:
Melanoma tumors frequently acquire LRP2/megalin expression, which
modulates melanoma cell proliferation and survival rates. Pigment
Cell Melanoma Res. 28:267–280. 2015. View Article : Google Scholar : PubMed/NCBI
|
32
|
Lu C, Bonome T, Li Y, Kamat AA, Han LY,
Schmandt R, Coleman RL, Gershenson DM, Jaffe RB, Birrer MJ and Sood
AK: Gene alterations identified by expression profiling in
tumor-associated endothelial cells from invasive ovarian carcinoma.
Cancer Res. 67:1757–1768. 2007. View Article : Google Scholar : PubMed/NCBI
|
33
|
Han L, Diehl A, Nguyen NK, Korangath P,
Teo W, Cho S, Kominsky S, Huso DL, Feigenbaum L, Rein A, et al: The
Notch pathway inhibits TGFβ signaling in breast cancer through
HEYL-mediated crosstalk. Cancer Res. 74:6509–6518. 2014. View Article : Google Scholar : PubMed/NCBI
|
34
|
Sun Y, Zhu D, Chen F, Qian M, Wei H, Chen
W and Xu J: SFRP2 augments WNT16B signaling to promote therapeutic
resistance in the damaged tumor microenvironment. Oncogene.
35:4321–4334. 2016. View Article : Google Scholar : PubMed/NCBI
|
35
|
O'Connell MJ, Lavery I, Yothers G, Paik S,
Clark-Langone KM, Lopatin M, Watson D, Baehner FL, Shak S, Baker J,
et al: Relationship between tumor gene expression and recurrence in
four independent studies of patients with stage II/III colon cancer
treated with surgery alone or surgery plus adjuvant fluorouracil
plus leucovorin. J Clin Oncol. 28:3937–3944. 2010. View Article : Google Scholar : PubMed/NCBI
|
36
|
Georges RB, Adwan H, Hamdi H, Hielscher T,
Linnemann U and Berger MR: The insulin-like growth factor binding
proteins 3 and 7 are associated with colorectal cancer and liver
metastasis. Cancer Biol Ther. 12:69–79. 2011. View Article : Google Scholar : PubMed/NCBI
|
37
|
Hsieh TH, Hsu CY, Tsai CF4, Chiu CC, Liang
SS, Wang TN, Kuo PL, Long CY and Tsai EM: A novel cell-penetrating
peptide suppresses breast tumorigenesis by inhibiting
β-catenin/LEF-1 signaling. Sci Rep. 6:191562016. View Article : Google Scholar : PubMed/NCBI
|
38
|
Cases O, Perea-Gomez A, Aguiar DP, Nykjaer
A, Amsellem S, Chandellier J, Umbhauer M, Cereghini S, Madsen M,
Collignon J, et al: Cubilin, a high affinity receptor for
fibroblast growth factor 8, is required for cell survival in the
developing vertebrate head. J Biol Chem. 288:16655–16670. 2013.
View Article : Google Scholar : PubMed/NCBI
|
39
|
Park YY, Lee SS, Lim JY, Kim SC, Kim SB,
Sohn BH, Chu IS, Oh SC, Park ES, Jeong W, et al: Comparison of
prognostic genomic predictors in colorectal cancer. PLoS One.
8:e607782013. View Article : Google Scholar : PubMed/NCBI
|