Open Access

MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review)

  • Authors:
    • Ming Li
    • Ying Wang
    • Yongsheng Song
    • Renge Bu
    • Bo Yin
    • Xiang Fei
    • Qizhen Guo
    • Bin Wu
  • View Affiliations

  • Published online on: February 13, 2015     https://doi.org/10.3892/or.2015.3799
  • Pages: 1571-1578
  • Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY_NC 3.0].

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Abstract

Despite recent advances in the understanding of the biology of renal cell carcinoma (RCC), successful surgical treatment and implementation of novel‑targeted therapies, the prognosis for RCC patients remains poor. Late presentation, tumor heterogeneity and in particular the lack of molecular biomarkers for early detection, classification and the surveillance of RCC treatments are major obstacles. The increasing knowledge regarding the functional role of microRNAs (miRNAs) in pathophysiological processes may provide an important link to the identification of suitable therapeutic targets and diagnostic/prognostic biomarkers for RCC. The aim of this review was to provide new insight into the function of miRNAs in the pathogenesis of RCC and to emphasize their potential as diagnostic and prognostic markers, as well as therapeutic targets.
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April-2015
Volume 33 Issue 4

Print ISSN: 1021-335X
Online ISSN:1791-2431

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Copy and paste a formatted citation
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Spandidos Publications style
Li M, Wang Y, Song Y, Bu R, Yin B, Fei X, Guo Q and Wu B: MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review). Oncol Rep 33: 1571-1578, 2015
APA
Li, M., Wang, Y., Song, Y., Bu, R., Yin, B., Fei, X. ... Wu, B. (2015). MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review). Oncology Reports, 33, 1571-1578. https://doi.org/10.3892/or.2015.3799
MLA
Li, M., Wang, Y., Song, Y., Bu, R., Yin, B., Fei, X., Guo, Q., Wu, B."MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review)". Oncology Reports 33.4 (2015): 1571-1578.
Chicago
Li, M., Wang, Y., Song, Y., Bu, R., Yin, B., Fei, X., Guo, Q., Wu, B."MicroRNAs in renal cell carcinoma: A systematic review of clinical implications (Review)". Oncology Reports 33, no. 4 (2015): 1571-1578. https://doi.org/10.3892/or.2015.3799