1
|
Morrow JJ and Khanna C: Osteosarcoma
genetics and epigenetics: Emerging biology and candidate therapies.
Crit Rev Oncog. 20:173–197. 2015. View Article : Google Scholar : PubMed/NCBI
|
2
|
Klein MJ and Siegal GP: Osteosarcoma:
Anatomic and histologic variants. Am J Clin Pathol. 125:555–581.
2006. View Article : Google Scholar : PubMed/NCBI
|
3
|
Yamamoto N and Tsuchiya H: Chemotherapy
for osteosarcoma - where does it come from? What is it? Where is it
going? Expert Opin Pharmacother. 14:2183–2193. 2013. View Article : Google Scholar : PubMed/NCBI
|
4
|
Ferrari S and Serra M: An update on
chemotherapy for osteosarcoma. Expert Opin Pharmacother.
16:2727–2736. 2015. View Article : Google Scholar : PubMed/NCBI
|
5
|
Geller DS and Gorlick R: Osteosarcoma: A
review of diagnosis, management, and treatment strategies. Clin Adv
Hematol Oncol. 8:705–718. 2010.PubMed/NCBI
|
6
|
Guo Z, Neilson LJ, Zhong H, Murray PS,
Zanivan S and Zaidel-Bar R: E-cadherin interactome complexity and
robustness resolved by quantitative proteomics. Sci Signal.
7:rs72014. View Article : Google Scholar : PubMed/NCBI
|
7
|
Li S, Chai Z, Li Y, Liu D, Bai Z, Li Y, Li
Y and Situ Z: BZW1, a novel proliferation regulator that
promotes growth of salivary muocepodermoid carcinoma. Cancer Lett.
284:86–94. 2009. View Article : Google Scholar : PubMed/NCBI
|
8
|
Polo Ml, Riggio M, May M, Rodríguez MJ,
Perrone MC, Stallings-Mann M, Kaen D, Frost M, Goetz M, Boughey J,
et al: Activation of PI3K/Akt/mTOR signaling in the tumor stroma
drives endocrine therapy-dependent breast tumor regression.
Oncotarget. 6:22081–22097. 2015. View Article : Google Scholar : PubMed/NCBI
|
9
|
Sharma N, Nanta R, Sharma J, Gunewardena
S, Singh KP, Shankar S and Srivastava RK: PI3K/AKT/mTOR and sonic
hedgehog pathways cooperate together to inhibit human pancreatic
cancer stem cell characteristics and tumor growth. Oncotarget.
6:32039–32060. 2015. View Article : Google Scholar : PubMed/NCBI
|
10
|
Sun CH, Chang YH and Pan CC: Activation of
the PI3K/Akt/mTOR pathway correlates with tumour progression and
reduced survival in patients with urothelial carcinoma of the
urinary bladder. Histopathology. 58:1054–1063. 2011. View Article : Google Scholar : PubMed/NCBI
|
11
|
Costa C, Pereira S, Lima L, Peixoto A,
Fernandes E, Neves D, Neves M, Gaiteiro C, Tavares A, da Costa Gil
RM, et al: Abnormal protein glycosylation and activated
PI3K/Akt/mTOR pathway: Role in bladder cancer prognosis and
targeted therapeutics. PLoS One. 10:e01412532015. View Article : Google Scholar : PubMed/NCBI
|
12
|
Isakoff MS, Bielack SS, Meltzer P and
Gorlick R: Osteosarcoma: Current treatment and a collaborative
pathway to success. J Clin Oncol. 33:3029–3035. 2015. View Article : Google Scholar : PubMed/NCBI
|
13
|
Whelan J, McTiernan A, Cooper N, Wong YK,
Francis M, Vernon S and Strauss SJ: Incidence and survival of
malignant bone sarcomas in England 1979–2007. Int J Cancer.
131:E508–E517. 2012. View Article : Google Scholar : PubMed/NCBI
|
14
|
Liu X, Choy E, Hornicek FJ, Yang S, Yang
C, Harmon D, Mankin H and Duan Z: ROCK1 as a potential therapeutic
target in osteosarcoma. J Orthop Res. 29:1259–1266. 2011.
View Article : Google Scholar : PubMed/NCBI
|
15
|
Nagao-Kitamoto H, Nagata M, Nagano S,
Kitamoto S, Ishidou Y, Yamamoto T, Nakamura S, Tsuru A, Abematsu M,
Fujimoto Y, et al: GLI2 is a novel therapeutic target for
metastasis of osteosarcoma. Int J Cancer. 136:1276–1284. 2015.
View Article : Google Scholar : PubMed/NCBI
|
16
|
Morioka K, Tanikawa C, Ochi K, Daigo Y,
Katagiri T, Kawano H, Kawaguchi H, Myoui A, Yoshikawa H, Naka N, et
al: Orphan receptor tyrosine kinase ROR2 as a potential therapeutic
target for osteosarcoma. Cancer Sci. 100:1227–1233. 2009.
View Article : Google Scholar : PubMed/NCBI
|
17
|
Li Z, Jia M, Wu X, Cui J, Pan A and Li L:
Overexpression of Trps1 contributes to tumor angiogenesis and poor
prognosis of human osteosarcoma. Diagn Pathol. 10:1672015.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Singh CR, Watanabe R, Zhou D, Jennings MD,
Fukao A, Lee B, Ikeda Y, Chiorini JA, Campbell SG, Ashe MP, et al:
Mechanisms of translational regulation by a human eIF5-mimic
protein. Nucleic Acids Res. 39:8314–8328. 2011. View Article : Google Scholar : PubMed/NCBI
|
19
|
Hiraishi H, Oatman J, Haller SL, Blunk L,
McGivern B, Morris J, Papadopoulos E, Gutierrez W, Gordon M,
Bokhari W, et al: Essential role of eIF5-mimic protein in animal
development is linked to control of ATF4 expression. Nucleic Acids
Res. 42:10321–10330. 2014. View Article : Google Scholar : PubMed/NCBI
|
20
|
Harding HP, Zhang Y, Zeng H, Novoa I, Lu
PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, et al: An
integrated stress response regulates amino acid metabolism and
resistance to oxidative stress. Mol Cell. 11:619–633. 2003.
View Article : Google Scholar : PubMed/NCBI
|
21
|
Wu CH, Sahoo D, Arvanitis C, Bradon N,
Dill DL and Felsher DW: Combined analysis of murine and human
microarrays and ChIP analysis reveals genes associated with the
ability of MYC to maintain tumorigenesis. PLoS Genet.
4:e10000902008. View Article : Google Scholar : PubMed/NCBI
|
22
|
Yu G, Huang B, Chen G and Mi Y:
Phosphatidylethanolamine-binding protein 4 promotes lung cancer
cells proliferation and invasion via PI3K/Akt/mTOR axis. J Thorac
Dis. 7:1806–1816. 2015.PubMed/NCBI
|
23
|
Xia Q, Zheng Y, Jiang W, Huang Z, Wang M,
Rodriguez R and Jin X: Valproic acid induces autophagy by
suppressing the Akt/mTOR pathway in human prostate cancer cells.
Oncol Lett. 12:1826–1832. 2016.PubMed/NCBI
|
24
|
Song R, Tian K, Wang W and Wang L: P53
suppresses cell proliferation, metastasis, and angiogenesis of
osteosarcoma through inhibition of the PI3K/AKT/mTOR pathway. Int J
Surg. 20:80–87. 2015. View Article : Google Scholar : PubMed/NCBI
|
25
|
Hu K, Dai HB and Qiu ZL: mTOR signaling in
osteosarcoma: Oncogenesis and therapeutic aspects (Review). Oncol
Rep. 36:1219–1225. 2016. View Article : Google Scholar : PubMed/NCBI
|
26
|
Hasanain M, Bhattacharjee A, Pandey P,
Ashraf R, Singh N, Sharma S, Vishwakarma AL, Datta D, Mitra K and
Sarkar J: α-Solanine induces ROS-mediated autophagy through
activation of endoplasmic reticulum stress and inhibition of
Akt/mTOR pathway. Cell Death Dis. 6:e18602015. View Article : Google Scholar : PubMed/NCBI
|