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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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December 2012 Volume 4 Issue 6

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Article Open Access

Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols

  • Authors:
    • Takahashi Masayoshi
    • Noritaka Wakui
    • Yasukiyo Sumino
  • View Affiliations / Copyright

    Affiliations: Division of Gastroenterology and Hepatology, Toho University Omori Medical Center, Tokyo 143-8541, Japan
  • Pages: 959-961
    |
    Published online on: September 13, 2012
       https://doi.org/10.3892/etm.2012.706
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Abstract

Hepatocellular carcinoma (HCC) is one of the most common cancer types worldwide. Percutaneous radiofrequency ablation (RFA) for HCC was introduced in Japan in 1999. It has been established as a major local treatment method worldwide including in Japan. On comparing outcomes between resection and RFA, they were comparable when cases were limited to those with 3 or fewer tumors of size 3 cm or smaller in many reports, based on which RFA has become the main treatment for small HCCs. RFA was introduced into our system at Toho University Medical Center Omori Hospital in 1999, and we treat nearly 200 HCC cases annually with RFA. Although individual medical facilities use their own methods of RFA, we would like to share our experience of RFA treatment protocols.
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1 

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Rossi S, Di Stasi M and Buscarini E: Percutaneous ultrasound-guided radiofrequency electrocautery for the treatment of small hepatocellular carcinoma. J Interv Radiol. 8:97–103. 1993.

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Shiina S, Teratani T, Obi S, et al: A randomized controlled trial of radiofrequency ablation with ethanol injection for small hepatocellular carcinoma. Gastroenterology. 129:122–130. 2005.

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Chen MS, Li JQ, Zheng Y, et al: A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg. 243:321–328. 2006.

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Hagisawa Y, Shiozawa K, Takahashi M, et al: Two-step radiofrequency ablation system by cool-tip electrode. Jpn J Med Pharm Sci. 54:163–165. 2005.(In Japanese).

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Wakui N, Iida K, Takayama R, et al: Cool-tip 10-mm electrode useful for radiofrequency ablation of hepatocellular carcinoma. Hepatogastroenterology. 56:1585–1591. 2009.

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Ikehara T, Iida K, Wakui N, Watanabe M and Sumino Y: Complications from radiofrequency ablation therapy for hepatocellular carcinoma: be reduced by output adjustment of the Cool-tip type RF ablation system? J Med Soc Toho. 55:298–305. 2008.(In Japanese).

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Yamasaki T, Kimura T, Kurokawa F, et al: Percutaneous radiofrequency ablation with cooled electrodes combined with hepatic arterial balloon occlusion in hepatocellular carcinoma. J Gastroenterol. 40:171–178. 2005.

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Takahashi M, Iida K, Wakui N, Takayama R, Shiozawa K and Sumino Y: Relationship between ablation zone of radiofrequency ablation and length of microbubble collapse in the post-vascular phase (Kupffer phase) of Sonazoid-enhanced ultrasonography in patients with hepatocellular carcinoma. Jpn J Med Ultrasonics. 38:637–646. 2011.(In Japanese with English abstract).

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Copy and paste a formatted citation
Spandidos Publications style
Masayoshi T, Wakui N and Sumino Y: Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols. Exp Ther Med 4: 959-961, 2012.
APA
Masayoshi, T., Wakui, N., & Sumino, Y. (2012). Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols. Experimental and Therapeutic Medicine, 4, 959-961. https://doi.org/10.3892/etm.2012.706
MLA
Masayoshi, T., Wakui, N., Sumino, Y."Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols". Experimental and Therapeutic Medicine 4.6 (2012): 959-961.
Chicago
Masayoshi, T., Wakui, N., Sumino, Y."Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols". Experimental and Therapeutic Medicine 4, no. 6 (2012): 959-961. https://doi.org/10.3892/etm.2012.706
Copy and paste a formatted citation
x
Spandidos Publications style
Masayoshi T, Wakui N and Sumino Y: Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols. Exp Ther Med 4: 959-961, 2012.
APA
Masayoshi, T., Wakui, N., & Sumino, Y. (2012). Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols. Experimental and Therapeutic Medicine, 4, 959-961. https://doi.org/10.3892/etm.2012.706
MLA
Masayoshi, T., Wakui, N., Sumino, Y."Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols". Experimental and Therapeutic Medicine 4.6 (2012): 959-961.
Chicago
Masayoshi, T., Wakui, N., Sumino, Y."Use of radiofrequency ablation in the treatment of hepatocellular carcinoma: Experience of ablation protocols". Experimental and Therapeutic Medicine 4, no. 6 (2012): 959-961. https://doi.org/10.3892/etm.2012.706
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