Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes

  • Authors:
    • Daliang Liu
    • Huijuan Jia
    • Wei Liu
    • Daqing Ma
    • Guangshan Tan
    • Wen He
    • Yucun Fu
    • Le-Xin Wang
  • View Affiliations

  • Published online on: January 27, 2014     https://doi.org/10.3892/etm.2014.1502
  • Pages: 917-922
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Abstract

The aim of the present study was to investigate the predictive value of multi-detector computed tomography angiography (MDCTA) on acute coronary artery events in patients with type 2 diabetes mellitus (T2DM). MDCTA was performed in 150 patients with T2DM (males, 74; mean age, 66±6.7 years for all patients) that had experienced atypical chest pains. After a follow-up period of at least 2 years, 55 patients were excluded from the study as they did not exhibit any coronary events. The remaining 95 patients were divided into the study group (n=28), that had experienced an acute coronary event such as acute coronary syndrome, or the control group (n=67) that had stable angina. There were no statistically significant differences in the degree of coronary artery lumen stenosis between the study and control groups (P=0.380). The proportion of calcified plaques in the study group was significantly lower compared with the control group (13.6 vs. 53.2%; P<0.001), while the proportion of soft plaques in the study group was significantly higher compared with the control group (37 vs. 9.3%; P<0.001). Type III plaques showed a sensitivity of 76.2% and a negative predictive value of 64.5% for acute coronary events. By contrast, type IV plaques had a sensitivity of 52.6% and a positive predictive value of 63% for chronic coronary events. Therefore, the results of the present study indicate that MDCTA may be used as a noninvasive modality for evaluating and predicting vulnerable coronary atherosclerosis plaques in patients with T2DM.
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2014-April
Volume 7 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Liu D, Jia H, Liu W, Ma D, Tan G, He W, Fu Y and Wang L: Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes. Exp Ther Med 7: 917-922, 2014
APA
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W. ... Wang, L. (2014). Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes. Experimental and Therapeutic Medicine, 7, 917-922. https://doi.org/10.3892/etm.2014.1502
MLA
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W., Fu, Y., Wang, L."Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes". Experimental and Therapeutic Medicine 7.4 (2014): 917-922.
Chicago
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W., Fu, Y., Wang, L."Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes". Experimental and Therapeutic Medicine 7, no. 4 (2014): 917-922. https://doi.org/10.3892/etm.2014.1502