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Article

Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes

  • Authors:
    • Daliang Liu
    • Huijuan Jia
    • Wei Liu
    • Daqing Ma
    • Guangshan Tan
    • Wen He
    • Yucun Fu
    • Le-Xin Wang
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China, Department of Radiology, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng, Shandong 252000, P.R. China, Central Experimental Laboratory, Liaocheng People's Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng, Shandong 252000, P.R. China, School of Biomedical Sciences, Charles Sturt University, Wagga Wagga 2650, Australia
  • Pages: 917-922
    |
    Published online on: January 27, 2014
       https://doi.org/10.3892/etm.2014.1502
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Abstract

The aim of the present study was to investigate the predictive value of multi-detector computed tomography angiography (MDCTA) on acute coronary artery events in patients with type 2 diabetes mellitus (T2DM). MDCTA was performed in 150 patients with T2DM (males, 74; mean age, 66±6.7 years for all patients) that had experienced atypical chest pains. After a follow-up period of at least 2 years, 55 patients were excluded from the study as they did not exhibit any coronary events. The remaining 95 patients were divided into the study group (n=28), that had experienced an acute coronary event such as acute coronary syndrome, or the control group (n=67) that had stable angina. There were no statistically significant differences in the degree of coronary artery lumen stenosis between the study and control groups (P=0.380). The proportion of calcified plaques in the study group was significantly lower compared with the control group (13.6 vs. 53.2%; P<0.001), while the proportion of soft plaques in the study group was significantly higher compared with the control group (37 vs. 9.3%; P<0.001). Type III plaques showed a sensitivity of 76.2% and a negative predictive value of 64.5% for acute coronary events. By contrast, type IV plaques had a sensitivity of 52.6% and a positive predictive value of 63% for chronic coronary events. Therefore, the results of the present study indicate that MDCTA may be used as a noninvasive modality for evaluating and predicting vulnerable coronary atherosclerosis plaques in patients with T2DM.
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Copy and paste a formatted citation
Spandidos Publications style
Liu D, Jia H, Liu W, Ma D, Tan G, He W, Fu Y and Wang L: Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes. Exp Ther Med 7: 917-922, 2014.
APA
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W. ... Wang, L. (2014). Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes. Experimental and Therapeutic Medicine, 7, 917-922. https://doi.org/10.3892/etm.2014.1502
MLA
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W., Fu, Y., Wang, L."Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes". Experimental and Therapeutic Medicine 7.4 (2014): 917-922.
Chicago
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W., Fu, Y., Wang, L."Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes". Experimental and Therapeutic Medicine 7, no. 4 (2014): 917-922. https://doi.org/10.3892/etm.2014.1502
Copy and paste a formatted citation
x
Spandidos Publications style
Liu D, Jia H, Liu W, Ma D, Tan G, He W, Fu Y and Wang L: Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes. Exp Ther Med 7: 917-922, 2014.
APA
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W. ... Wang, L. (2014). Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes. Experimental and Therapeutic Medicine, 7, 917-922. https://doi.org/10.3892/etm.2014.1502
MLA
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W., Fu, Y., Wang, L."Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes". Experimental and Therapeutic Medicine 7.4 (2014): 917-922.
Chicago
Liu, D., Jia, H., Liu, W., Ma, D., Tan, G., He, W., Fu, Y., Wang, L."Value of multi-detector computed tomography angiography in predicting acute cardiac events in patients with type 2 diabetes". Experimental and Therapeutic Medicine 7, no. 4 (2014): 917-922. https://doi.org/10.3892/etm.2014.1502
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