1
|
Tan SL, Pause A, Shi Y and Sonenberg N:
Hepatitis C therapeutics: current status and emerging strategies.
Nat Rev Drug Discov. 1:867–881. 2002. View
Article : Google Scholar : PubMed/NCBI
|
2
|
Alter HJ and Seef LB: Recovery,
persistence, and sequelae in hepatitis C virus infection: a
perspective on long-term outcome. Semin Liver Dis. 20:17–35. 2000.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Lauer GM and Walker BD: Hepatitis C virus
infection. N Engl J Med. 345:41–52. 2001. View Article : Google Scholar : PubMed/NCBI
|
4
|
El-Serag HB: Hepatocellular carcinoma and
hepatitis C in the United States. Hepatology. 36(5 Suppl 1):
S74–S83. 2002. View Article : Google Scholar : PubMed/NCBI
|
5
|
Bowen DG and Walker CM: Adaptive immune
responses in acute and chronic hepatitis C virus infection. Nature.
436:946–952. 2005. View Article : Google Scholar : PubMed/NCBI
|
6
|
Stone TW and Darlington LG: Endogenous
kynurenines as targets for drug discovery and development. Nat Rev
Drug Discov. 1:609–620. 2002. View
Article : Google Scholar : PubMed/NCBI
|
7
|
Robinson CM, Shirey KA and Carlin JM:
Synergistic transcriptional activation of indoleamine dioxygenase
by IFG-gamma and tumor necrosis factor-alpha. J Interferon Cytokine
Res. 23:413–421. 2003. View Article : Google Scholar : PubMed/NCBI
|
8
|
Abbate I, Romano M, Longo R, et al:
Endogenous levels of mRNA for IFNs and IFN-related genes in hepatic
biopsies of chronic HCV-infected and non-alcoholic steatohepatitis
patients. J Med Virol. 70:581–587. 2003. View Article : Google Scholar : PubMed/NCBI
|
9
|
Grohmann U, Fallarino F and Puccetti P:
Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol.
24:242–248. 2003. View Article : Google Scholar : PubMed/NCBI
|
10
|
Munn DH, Sharma MD and Mellor AL: Ligation
of B7-1/B7-2 by human CD4+ T cells trigger indoleamine
2,3-dioxgenase activity in dendritic cells. J Immunol.
172:4100–4110. 2004. View Article : Google Scholar : PubMed/NCBI
|
11
|
Mellor AL and Munn DH: IDO expression by
DCs: tolerance and tryptophan catabolism. Nat Rev Immunol.
4:762–774. 2004. View
Article : Google Scholar : PubMed/NCBI
|
12
|
Uyttenhove C, Pilotte L, Théate I, et al:
Evidence for a tumoral immune resistance mechanism based on
tryptophan degradation by indoleamine 2,3-dioxgenase. Nat Med.
9:1269–1274. 2003. View
Article : Google Scholar : PubMed/NCBI
|
13
|
Larrea E, Riezu-Boj JI, Gil-Guerrero L, et
al: Upregulation of indoleamine 2,3-dioxgenase in hepatitis C virus
infection. J Virol. 81:3662–3666. 2007. View Article : Google Scholar : PubMed/NCBI
|
14
|
Sugimoto K, Ikeda F, Stadanlick J, et al:
Suppression of HCV-specific T-cells without differential hierarchy
demonstrated ex vivo in persistent HCV infection. Hepatology.
38:1437–1448. 2003.PubMed/NCBI
|
15
|
Perrella A, Vitiello L, Atripaldi L, et
al: Elevated CD4+/CD25+ T cell frequency and
function during acute hepatitis C presage chronic evolution. Gut.
55:1370–1371. 2006. View Article : Google Scholar : PubMed/NCBI
|
16
|
Ulsenheimer A, Gerlach JT, Gruener NH, et
al: Detection of functionally altered hepatitis C virus-specific
CD4 T cells in acute and chronic hepatitis C. Hepatology.
37:1189–1198. 2003. View Article : Google Scholar : PubMed/NCBI
|
17
|
Cabrera R, Tu Z, Xu Y, et al: An
immunomodulatory role for CD4+, CD25+,
regulatory T lymphocytes in hepatitis C virus infection.
Hepatology. 40:1062–1071. 2004. View Article : Google Scholar : PubMed/NCBI
|
18
|
Boettler T, Spangenberg HC,
Neumann-Haefelin C, et al: T cells with a
CD4+CD25+ regulatory phenotype suppress in
vitro proliferation of virus-specific CD+ T cells during
chronic hepatitis C virus infection. J Virol. 79:7860–7867. 2005.
View Article : Google Scholar : PubMed/NCBI
|
19
|
Bolacchi F, Sinistro A, Ciaprini C, et al:
Increased hepatitis C virus (HCV)-specific CD4+
CD25+ regulatory T lymphocytes and reduced HCV-specific
CD4+ T cell response in HCV-infected patients with
normal versus abnormal alanine aminotransferase levels. Clin Exp
Immunol. 144:188–196. 2006. View Article : Google Scholar : PubMed/NCBI
|
20
|
Ebinuma H, Nakamoto N, Li Y, et al:
Identification and in vitro expansion of functional
antigen-specific CD25+ FoxP3+ regulatory
T-cells in hepatitis C virus infection. J Virol. 82:5043–5053.
2008. View Article : Google Scholar : PubMed/NCBI
|
21
|
Fallarino F, Grohmann U, You S, et al: The
combined effects of tryptophan starvation and tryptophan
catabolites down-regulate T-cell receptor zeta-chain and induce a
regulatory phenotype in naïve T cells. J Immunol. 176:6752–6761.
2006. View Article : Google Scholar : PubMed/NCBI
|
22
|
Hill M, Tanguy-Royer S, Royer P, et al:
IDO expands human CD4+CD25 high regulatory T cells by
promoting maturation of LPS-treated dendritic cells. Eur J Immunol.
37:3054–3062. 2007. View Article : Google Scholar : PubMed/NCBI
|
23
|
Sharma MD, Baban B, Chandler P, et al:
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes
directly activate mature Tregs via indoleamine 2,3-dioxgenase. J
Clin Invest. 117:2570–2582. 2007. View
Article : Google Scholar : PubMed/NCBI
|
24
|
Terness P, Bauer TM, Röse L, et al:
Inhibition of allogenic T cell proliferation by indoleamine
2,3-dioxgenase-expressing dendritic cells: mediation of suppression
by tryptophan metabolites. J Exp Med. 447–457. 2002. View Article : Google Scholar
|
25
|
Munn DH and Mellor AL: IDO and tolerance
to tumors. Trends Mol Med. 10:15–18. 2004. View Article : Google Scholar : PubMed/NCBI
|
26
|
Takikawa O, Kuroiwa T, Yamazaki F and Kido
R: Mechanism of interferon-gamma action. characterization of
indoleamine 2,3-dioxygenase in cultured human cells induced by
interferon-gamma and evaluation of the enzyme-mediated tryptophan
degradation in its anticellular activity. J Biol Chem.
263:2041–2048. 1988.PubMed/NCBI
|
27
|
Grant RS, Naif H, Thuruthyil SJ, et al:
Induction of indolamine 2,3-dioxygenase in primary human
macrophages by human immunodeficiency virus type 1 is strain
dependent. J Virol. 74:4110–4115. 2000. View Article : Google Scholar
|
28
|
Fallarino F, Vacca C, Orabona C, et al:
Functional expression of indoleamine 2,3-dioxygenase by murine CD8
alpha+ dendritic cells. Int Immunol. 14:65–68. 2002.
View Article : Google Scholar
|
29
|
Grohmann U, Bianchi R, Orabona C, et al:
Functional plasticity of dendritic cell subsets as mediated by CD40
versus B7 activation. J Immunol. 171:2581–2587. 2003. View Article : Google Scholar : PubMed/NCBI
|
30
|
Pan K, Wang H, Chen MS, et al: Expression
and prognosis role of indoleamine 2,3-dioxygenase in hepatocellular
carcinoma. J Cancer Res Clin. 134:1247–1253. 2008. View Article : Google Scholar
|
31
|
Day CL, Lauer GM, Robbins GK, et al: Broad
specificity of virus-specific CD4+ T-helper-cell responses in
resolved hepatitis C virus infection. J Virol. 76:12584–12595.
2002. View Article : Google Scholar : PubMed/NCBI
|
32
|
Semmo N and Klenerman P: CD4+ T cell
responses in hepatitis C virus infection. World J Gastroenterol.
13:4831–4838. 2007.PubMed/NCBI
|
33
|
Chang KM, Thimme R, Melpolder JJ, Oldach
D, et al: Differential CD4 (+) and CD8(+) T-cell responsiveness in
hepatitis C virus infection. Hepatology. 33:267–276. 2001.
View Article : Google Scholar
|
34
|
Perrella A, Vitiello L, Atripaldi L, et
al: Elevated CD4+/CD25+ T cell frequency and
function during acute hepatitis C presage chronic evolution. Gut.
55:1370–1371. 2006. View Article : Google Scholar : PubMed/NCBI
|
35
|
Ino K, Yoshida N, Kajiyama H, et al:
Indoleamine 2,3-dioxygenase is a novel prognostic indicator for
dendometrial cancer. Br J Cancer. 95:1555–1561. 2006. View Article : Google Scholar : PubMed/NCBI
|
36
|
Brandacher G, Perathoner A, Ladurner R, et
al: Prognostic value of indoleamine 2,3-dioxygenase expression in
colorectal cancer: effect on tumor-infiltrating T cells. Clin
Cancer Res. 12:1144–1151. 2006. View Article : Google Scholar : PubMed/NCBI
|
37
|
Ishio T, Goto S, Tahara K, et al:
Immunoactivative role of indoleamine 2,3-dioxygenase in human
hepatocellular carcinoma. J Gastroenterol Hepatol. 19:319–326.
2004. View Article : Google Scholar : PubMed/NCBI
|