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Experimental and Therapeutic Medicine
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International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Case Report Open Access

A confirmed severe case of human infection with avian-origin influenza H7N9: A case report

  • Authors:
    • Hui‑Fang Cao
    • Zong‑Hui Liang
    • Ying Feng
    • Zi‑Nan Zhang
    • Jing Xu
    • He He
  • View Affiliations / Copyright

    Affiliations: Department of Respiratory Medicine, Jingan District Centre Hospital of Shanghai, Jingan Branch of Huashan Hospital Affiliated to Fudan University, Shanghai 200040, P.R. China, Department of Radiology, Jingan District Centre Hospital of Shanghai, Jingan Branch of Huashan Hospital Affiliated to Fudan University, Shanghai 200040, P.R. China
    Copyright: © Cao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 693-696
    |
    Published online on: December 30, 2014
       https://doi.org/10.3892/etm.2014.2159
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Abstract

A male patient, aged 77 years, was admitted to hospital with the chief complaint of persistent hyperpyrexia that had presented for four days. The patient also suffered from hypoxemia, and a large white shadow in the left lung was observed on a chest radiograph, indicating inflammation. No therapeutic effect was observed with anti‑infection treatment. The patient admitted a history of direct contact with live chickens two weeks prior to hospital admission. The day after admission to the Jingnan District Centre Hospital of Shanghai (Shanghai, China), the patient was diagnosed with severe H7N9 avian influenza infection by nasopharyngeal swab and blood sampling detection. Although the patient received anti‑infective drugs, intubated assisted ventilation and circulation support, the condition of the patient continued to rapidly deteriorate. Oxygen saturation decreased and gastrointestinal bleeding occurred, with the body temperature fluctuating between 39 and 40˚C. By day 6 after admission, the patient presented with circulatory failure, with liver and renal failure. On day 7, the blood pressure of the patient was unable to be measured, and the patient was diagnosed with multiple organ dysfunction. Subsequently, clinical death was declared with the patient exhibiting asystole and no spontaneous breathing.
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Hackett H, Bialasiewicz S, Jacob K, et al: Screening for H7N9 influenza A by matrix gene-based real-time reverse-transcription PCR. J Virol Methods. 195:123–125. 2014. View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Cao HF, Liang ZH, Feng Y, Zhang ZN, Xu J and He H: A confirmed severe case of human infection with avian-origin influenza H7N9: A case report. Exp Ther Med 9: 693-696, 2015.
APA
Cao, H., Liang, Z., Feng, Y., Zhang, Z., Xu, J., & He, H. (2015). A confirmed severe case of human infection with avian-origin influenza H7N9: A case report. Experimental and Therapeutic Medicine, 9, 693-696. https://doi.org/10.3892/etm.2014.2159
MLA
Cao, H., Liang, Z., Feng, Y., Zhang, Z., Xu, J., He, H."A confirmed severe case of human infection with avian-origin influenza H7N9: A case report". Experimental and Therapeutic Medicine 9.3 (2015): 693-696.
Chicago
Cao, H., Liang, Z., Feng, Y., Zhang, Z., Xu, J., He, H."A confirmed severe case of human infection with avian-origin influenza H7N9: A case report". Experimental and Therapeutic Medicine 9, no. 3 (2015): 693-696. https://doi.org/10.3892/etm.2014.2159
Copy and paste a formatted citation
x
Spandidos Publications style
Cao HF, Liang ZH, Feng Y, Zhang ZN, Xu J and He H: A confirmed severe case of human infection with avian-origin influenza H7N9: A case report. Exp Ther Med 9: 693-696, 2015.
APA
Cao, H., Liang, Z., Feng, Y., Zhang, Z., Xu, J., & He, H. (2015). A confirmed severe case of human infection with avian-origin influenza H7N9: A case report. Experimental and Therapeutic Medicine, 9, 693-696. https://doi.org/10.3892/etm.2014.2159
MLA
Cao, H., Liang, Z., Feng, Y., Zhang, Z., Xu, J., He, H."A confirmed severe case of human infection with avian-origin influenza H7N9: A case report". Experimental and Therapeutic Medicine 9.3 (2015): 693-696.
Chicago
Cao, H., Liang, Z., Feng, Y., Zhang, Z., Xu, J., He, H."A confirmed severe case of human infection with avian-origin influenza H7N9: A case report". Experimental and Therapeutic Medicine 9, no. 3 (2015): 693-696. https://doi.org/10.3892/etm.2014.2159
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