Severe airflow obstruction in a patient with ulcerative colitis and toxic epidermal necrolysis: A case report

  • Authors:
    • Shijima Taguchi
    • Junichi Furuta
    • Gen Ohara
    • Katsunori Kagohashi
    • Hiroaki Satoh
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  • Published online on: February 24, 2015     https://doi.org/10.3892/etm.2015.2307
  • Pages: 1944-1946
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Abstract

Bronchiolitis is a rare condition mainly affecting the intralobular conducting and transitional small airways. The present study describes a case of severe airflow limitation in a patient with ulcerative colitis who developed toxic epidermal necrolysis following mesalazine therapy. Forced expiratory volume in one second was decreased and a flow‑volume curve showed airflow limitation, but the single‑breath diffusing capacity of the lung for carbon monoxide (DLCO) and DLCO divided by alveolar volume (DLCO/VA) were not decreased. This rare clinical condition should be considered as a differential diagnosis for subjects presenting with sub‑acutely developed airflow obstruction if the findings in chest computed tomography scans demonstrate hyperinflation but few low‑attenuation areas. Relatively well‑preserved DLCO and DLCO/VA provide a clue to establishing the correct diagnosis.
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May-2015
Volume 9 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Taguchi S, Furuta J, Ohara G, Kagohashi K and Satoh H: Severe airflow obstruction in a patient with ulcerative colitis and toxic epidermal necrolysis: A case report. Exp Ther Med 9: 1944-1946, 2015
APA
Taguchi, S., Furuta, J., Ohara, G., Kagohashi, K., & Satoh, H. (2015). Severe airflow obstruction in a patient with ulcerative colitis and toxic epidermal necrolysis: A case report. Experimental and Therapeutic Medicine, 9, 1944-1946. https://doi.org/10.3892/etm.2015.2307
MLA
Taguchi, S., Furuta, J., Ohara, G., Kagohashi, K., Satoh, H."Severe airflow obstruction in a patient with ulcerative colitis and toxic epidermal necrolysis: A case report". Experimental and Therapeutic Medicine 9.5 (2015): 1944-1946.
Chicago
Taguchi, S., Furuta, J., Ohara, G., Kagohashi, K., Satoh, H."Severe airflow obstruction in a patient with ulcerative colitis and toxic epidermal necrolysis: A case report". Experimental and Therapeutic Medicine 9, no. 5 (2015): 1944-1946. https://doi.org/10.3892/etm.2015.2307