Open Access

Percutaneous coronary intervention strategies and prognosis for graft lesions following coronary artery bypass grafting

  • Authors:
    • Yin Liu
    • Xiujun Zhou
    • Hua Jiang
    • Mingdong Gao
    • Lin Wang
    • Yutian Shi
    • Jing Gao
  • View Affiliations

  • Published online on: March 16, 2015     https://doi.org/10.3892/etm.2015.2366
  • Pages: 1656-1664
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The purpose of this study was to compare the prognosis of graft-percutaneous coronary intervention (PCI) and native vessel (NV)‑PCI, drug‑eluting stents (DESs) and bare‑metal stents (BMSs) for the treatment of graft lesions following coronary artery bypass grafting (CABG), and to determine the risk factors for major adverse cardiac events (MACEs). A total of 289 patients who underwent PCI following CABG between August 2005 and March 2010 were retrospectively analyzed. The effects on survival were compared among patients who underwent NV‑ and graft‑PCI, and DES and BMS implantation. Additionally, the risk factors for MACEs following PCI for graft lesions were analyzed. The findings showed that MACE‑free and revascularization‑free survival rates were significantly higher in the NV‑PCI group compared with those in the graft‑PCI group. There were 63 cases (29.0%) of MACEs in the DES group and 25 cases (52.1%) in the BMS group. In patients undergoing NV‑PCI, the DES group had significantly fewer MACEs and less target vessel revascularization (TVR) than the BMS group. In patients undergoing graft‑PCI, the DES group showed a tendency for fewer MACEs and a lower incidence of cardiac mortality, myocardial infarction and TVR compared with the BMS group. Diabetes, an age of >70 years and graft‑PCI were independent risk factors for MACEs in patients post‑PCI. It is concluded that NV‑PCI has superior long‑term outcomes compared with graft‑PCI, and should therefore be considered as the first‑line treatment for graft disease following CABG. Despite this, graft‑PCI remains a viable option. DESs are the first choice for graft‑PCI due to their safety and efficacy and their association with reduced mortality and MACE rate. Diabetes, older age and graft‑PCI are independent risk factors for MACEs in patients post‑CABG who are undergoing revascularization.
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May-2015
Volume 9 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Copy and paste a formatted citation
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Spandidos Publications style
Liu Y, Zhou X, Jiang H, Gao M, Wang L, Shi Y and Gao J: Percutaneous coronary intervention strategies and prognosis for graft lesions following coronary artery bypass grafting. Exp Ther Med 9: 1656-1664, 2015
APA
Liu, Y., Zhou, X., Jiang, H., Gao, M., Wang, L., Shi, Y., & Gao, J. (2015). Percutaneous coronary intervention strategies and prognosis for graft lesions following coronary artery bypass grafting. Experimental and Therapeutic Medicine, 9, 1656-1664. https://doi.org/10.3892/etm.2015.2366
MLA
Liu, Y., Zhou, X., Jiang, H., Gao, M., Wang, L., Shi, Y., Gao, J."Percutaneous coronary intervention strategies and prognosis for graft lesions following coronary artery bypass grafting". Experimental and Therapeutic Medicine 9.5 (2015): 1656-1664.
Chicago
Liu, Y., Zhou, X., Jiang, H., Gao, M., Wang, L., Shi, Y., Gao, J."Percutaneous coronary intervention strategies and prognosis for graft lesions following coronary artery bypass grafting". Experimental and Therapeutic Medicine 9, no. 5 (2015): 1656-1664. https://doi.org/10.3892/etm.2015.2366