search button
Open Access

Comparison of the short‑term efficacy of sequential treatment with intravesical single‑port laparoscopic partial cystectomy with bladder preservation or open partial cystectomy in combination with cisplatin plus gemcitabine chemotherapy

  • Authors:
    • Hai‑Xing Mai
    • Jun‑Le Liu
    • Shu‑Jun Pei
    • Li Zhao
    • Nan Qu
    • Jin‑Kai Dong
    • Biao Chen
    • Ya‑Lin Wang
    • Cheng Huang
    • Li‑Jun Chen

  • View Affiliations

  • Published online on: April 24, 2015     https://doi.org/10.3892/etm.2015.2448
  • Pages: 74-80

  • Copyright: © Mai et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

This study aimed to assess the short‑term efficacy of sequential therapy for T2/T3a bladder cancer with intravesical single‑port laparoscopic partial cystectomy or open partial cystectomy combined with cisplatin plus gemcitabine (GC) chemotherapy in a prospective randomized controlled study. Thirty patients with bladder cancer who underwent open partial cystectomy (group A) or single‑port laparoscopic partial cystectomy (group B) and received standard GC chemotherapy were analyzed. Perioperative functional indicators and tumor recurrence during a 1‑year postoperative follow‑up were compared between the two groups. The baseline characteristics were comparable between the two groups. The mean operative time, amount of blood loss and duration of hospital stay were 90.3 min, 182.0 ml and 7.3 days, respectively, for group A, and 105.3 min, 49.3 ml and 5.8 days, respectively, for group B. No secondary postoperative bleeding, urine leakage, wound infection or other complications were observed in the two groups. Postoperative scarring was not evident in group B. The overall incidence of surgical complications, tumor recurrence rate and complications during chemotherapy in the postoperative follow‑up period of 12 months were similar between the two groups. Single‑port laparoscopic partial cystectomy surgery is an idea surgical method for the treatment of invasive bladder cancer, with good surgical effect, minimal invasiveness, rapid recovery and short hospital stay. The data from 1‑year postoperative follow‑up showed that laparoscopic surgery was superior with regard to perioperative bleeding, postoperative recovery and duration of indwelling urinary catheter use. However, regarding the tumor recurrence rate, long‑term comparative details are required to determine the effect of laparoscopic surgery.
View Figures
View References

Related Articles

Journal Cover

July-2015
Volume 10 Issue 1

Print ISSN: 1792-0981
Online ISSN:1792-1015

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 2.7
  • Ranked Medicine Research and Experimental
    (total number of cites)
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
Mai HX, Liu JL, Pei SJ, Zhao L, Qu N, Dong JK, Chen B, Wang YL, Huang C, Chen LJ, Chen LJ, et al: Comparison of the short‑term efficacy of sequential treatment with intravesical single‑port laparoscopic partial cystectomy with bladder preservation or open partial cystectomy in combination with cisplatin plus gemcitabine chemotherapy. Exp Ther Med 10: 74-80, 2015
APA
Mai, H., Liu, J., Pei, S., Zhao, L., Qu, N., Dong, J. ... Chen, L. (2015). Comparison of the short‑term efficacy of sequential treatment with intravesical single‑port laparoscopic partial cystectomy with bladder preservation or open partial cystectomy in combination with cisplatin plus gemcitabine chemotherapy. Experimental and Therapeutic Medicine, 10, 74-80. https://doi.org/10.3892/etm.2015.2448
MLA
Mai, H., Liu, J., Pei, S., Zhao, L., Qu, N., Dong, J., Chen, B., Wang, Y., Huang, C., Chen, L."Comparison of the short‑term efficacy of sequential treatment with intravesical single‑port laparoscopic partial cystectomy with bladder preservation or open partial cystectomy in combination with cisplatin plus gemcitabine chemotherapy". Experimental and Therapeutic Medicine 10.1 (2015): 74-80.
Chicago
Mai, H., Liu, J., Pei, S., Zhao, L., Qu, N., Dong, J., Chen, B., Wang, Y., Huang, C., Chen, L."Comparison of the short‑term efficacy of sequential treatment with intravesical single‑port laparoscopic partial cystectomy with bladder preservation or open partial cystectomy in combination with cisplatin plus gemcitabine chemotherapy". Experimental and Therapeutic Medicine 10, no. 1 (2015): 74-80. https://doi.org/10.3892/etm.2015.2448