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Article

Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro

  • Authors:
    • Biao Luo
    • Fei Liao
    • Yanchun Hu
    • Xi Liu
    • Yajun He
    • Lei Wu
    • Hui Tan
    • Lijuan Luo
    • Yancheng Zhou
    • Quan Mo
    • Junliang Deng
    • Yahui Wei
  • View Affiliations / Copyright

    Affiliations: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China, Ganzi Institute of Animal Husbandary, Kangding, Sichuan 626000, P.R. China, Key Laboratory of Resource Biology and Biotechnology in Western China, School of Life Science, Northwest University, Xi'an, Shaanxi 710069, P.R. China
  • Pages: 247-250
    |
    Published online on: May 19, 2015
       https://doi.org/10.3892/etm.2015.2503
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Abstract

The aim of the present study was to investigate the acaricidal activity of Ligularia virgaurea. An extract was prepared by refluxing with ethanol and steam distillation, and its toxic effect was tested in vitro against Sarcoptes scabiei. The data from the toxicity tests were analyzed using a complementary log‑log (CLL) model. The ethanol extract exhibited strong acaricidal activity against these mites; at a concentration of 2 g/ml it killed all S. scabiei within 2 h and at 1 g/ml it killed all S. scabiei within 6 h. Similarly, 2, 1, 0.5 and 0.25 g/ml concentrations of the extract had strong toxicity against S. scabiei, with median lethal time (LT50) values of 0.716, 1.741, 2.968 and 4.838 h, respectively. The median lethal concentration (LC50) values were 1.388, 0.624, 0.310 and 0.213 g/ml for Scabies mite in 1, 2, 4 and 6 h, respectively. The results indicate that the L. virgaurea extract has strong acaricidal activity and may be exploited as a novel treatment for the effective control of acariasis in animals.
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Copy and paste a formatted citation
Spandidos Publications style
Luo B, Liao F, Hu Y, Liu X, He Y, Wu L, Tan H, Luo L, Zhou Y, Mo Q, Mo Q, et al: Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro. Exp Ther Med 10: 247-250, 2015.
APA
Luo, B., Liao, F., Hu, Y., Liu, X., He, Y., Wu, L. ... Wei, Y. (2015). Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro. Experimental and Therapeutic Medicine, 10, 247-250. https://doi.org/10.3892/etm.2015.2503
MLA
Luo, B., Liao, F., Hu, Y., Liu, X., He, Y., Wu, L., Tan, H., Luo, L., Zhou, Y., Mo, Q., Deng, J., Wei, Y."Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro". Experimental and Therapeutic Medicine 10.1 (2015): 247-250.
Chicago
Luo, B., Liao, F., Hu, Y., Liu, X., He, Y., Wu, L., Tan, H., Luo, L., Zhou, Y., Mo, Q., Deng, J., Wei, Y."Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro". Experimental and Therapeutic Medicine 10, no. 1 (2015): 247-250. https://doi.org/10.3892/etm.2015.2503
Copy and paste a formatted citation
x
Spandidos Publications style
Luo B, Liao F, Hu Y, Liu X, He Y, Wu L, Tan H, Luo L, Zhou Y, Mo Q, Mo Q, et al: Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro. Exp Ther Med 10: 247-250, 2015.
APA
Luo, B., Liao, F., Hu, Y., Liu, X., He, Y., Wu, L. ... Wei, Y. (2015). Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro. Experimental and Therapeutic Medicine, 10, 247-250. https://doi.org/10.3892/etm.2015.2503
MLA
Luo, B., Liao, F., Hu, Y., Liu, X., He, Y., Wu, L., Tan, H., Luo, L., Zhou, Y., Mo, Q., Deng, J., Wei, Y."Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro". Experimental and Therapeutic Medicine 10.1 (2015): 247-250.
Chicago
Luo, B., Liao, F., Hu, Y., Liu, X., He, Y., Wu, L., Tan, H., Luo, L., Zhou, Y., Mo, Q., Deng, J., Wei, Y."Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro". Experimental and Therapeutic Medicine 10, no. 1 (2015): 247-250. https://doi.org/10.3892/etm.2015.2503
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