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Article

Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease

  • Authors:
    • Igor Govorov
    • Lena Ekelund
    • Roza Chaireti
    • Petra Elfvinge
    • Margareta Holmström
    • Katarina Bremme
    • Miriam Mints
  • View Affiliations / Copyright

    Affiliations: Department of Women's and Children's Health, Karolinska University Hospital, Stockholm 171 76, Sweden, Department of Molecular Medicine and Surgery, Karolinska Institute, Karolinska University Hospital, Stockholm 171 76, Sweden, Coagulation Unit, Department of Medicine, Karolinska University Hospital, Stockholm 171 76, Sweden
  • Pages: 1923-1929
    |
    Published online on: March 10, 2016
       https://doi.org/10.3892/etm.2016.3144
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Abstract

Women with the inherited bleeding disorder von Willebrand's disease (VWD) face gender-specific hemostatic challenges during menstruation. Heavy menstrual bleeding (HMB) can negatively affect their overall life activities and the health-associated quality of life. The purpose of the present study was to investigate whether women with VWD experienced HMB and an impaired health‑associated quality of life. The study subjects were recruited from the Coagulation Unit of Karolinska University Hospital. Information was retrieved from various self‑administered forms and medical records. Of the 30 women (18‑52 years) that were included in the present study, 50% suffered from HMB, although the majority received treatment for HMB. In addition, almost all the included women perceived limitations in the overall life activities due to menstruation. The health-associated quality of life for women with HMB was significantly lower (P<0.10) with regards to ‘bodily pain’ compared with Swedish women of the general population. In conclusion, women with VWD experienced reduced health-associated quality of life as a result of HMB. Therefore, preventing limitations in overall life activities and improving their health-associated quality of life thorough counseling on menstrual bleeding is important for women with VWD.
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Copy and paste a formatted citation
Spandidos Publications style
Govorov I, Ekelund L, Chaireti R, Elfvinge P, Holmström M, Bremme K and Mints M: Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease. Exp Ther Med 11: 1923-1929, 2016.
APA
Govorov, I., Ekelund, L., Chaireti, R., Elfvinge, P., Holmström, M., Bremme, K., & Mints, M. (2016). Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease. Experimental and Therapeutic Medicine, 11, 1923-1929. https://doi.org/10.3892/etm.2016.3144
MLA
Govorov, I., Ekelund, L., Chaireti, R., Elfvinge, P., Holmström, M., Bremme, K., Mints, M."Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease". Experimental and Therapeutic Medicine 11.5 (2016): 1923-1929.
Chicago
Govorov, I., Ekelund, L., Chaireti, R., Elfvinge, P., Holmström, M., Bremme, K., Mints, M."Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease". Experimental and Therapeutic Medicine 11, no. 5 (2016): 1923-1929. https://doi.org/10.3892/etm.2016.3144
Copy and paste a formatted citation
x
Spandidos Publications style
Govorov I, Ekelund L, Chaireti R, Elfvinge P, Holmström M, Bremme K and Mints M: Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease. Exp Ther Med 11: 1923-1929, 2016.
APA
Govorov, I., Ekelund, L., Chaireti, R., Elfvinge, P., Holmström, M., Bremme, K., & Mints, M. (2016). Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease. Experimental and Therapeutic Medicine, 11, 1923-1929. https://doi.org/10.3892/etm.2016.3144
MLA
Govorov, I., Ekelund, L., Chaireti, R., Elfvinge, P., Holmström, M., Bremme, K., Mints, M."Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease". Experimental and Therapeutic Medicine 11.5 (2016): 1923-1929.
Chicago
Govorov, I., Ekelund, L., Chaireti, R., Elfvinge, P., Holmström, M., Bremme, K., Mints, M."Heavy menstrual bleeding and health-associated quality of life in women with von Willebrand's disease". Experimental and Therapeutic Medicine 11, no. 5 (2016): 1923-1929. https://doi.org/10.3892/etm.2016.3144
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