Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report

  • Authors:
    • Xuejing Zhu
    • Hong Liu
    • Shuguang Yuan
    • Xiangqing Xu
    • Zhen Dong
    • Fuyou Liu
  • View Affiliations

  • Published online on: March 15, 2016     https://doi.org/10.3892/etm.2016.3161
  • Pages: 1871-1874
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Abstract

A 38-year-old Chinese man was admitted to the Second Xiangya Hospital of the Central South University (Changsha, China) with heavy proteinuria and rapidly progressing renal failure with nephrotic syndrome. An initial renal biopsy identified collapsing glomerulopathy (CG) with characteristic segmental collapse of the glomerular tuft and marked hypertrophy and hyperplasia of the visceral epithelial cells. A second renal biopsy showed dilation of glomerular capillary loops as a result of effective treatment with rapamycin and anti‑viral therapy. Serology for the coxsackie virus antibody was positive when the collapsing lesion was present, and became negative following treatment, which indicated a strong association between the development of CG and coxsackie virus infection. To the best of our knowledge, this is the first case report of CG associated with coxsackie virus infection.
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May-2016
Volume 11 Issue 5

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Zhu X, Liu H, Yuan S, Xu X, Dong Z and Liu F: Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report. Exp Ther Med 11: 1871-1874, 2016
APA
Zhu, X., Liu, H., Yuan, S., Xu, X., Dong, Z., & Liu, F. (2016). Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report. Experimental and Therapeutic Medicine, 11, 1871-1874. https://doi.org/10.3892/etm.2016.3161
MLA
Zhu, X., Liu, H., Yuan, S., Xu, X., Dong, Z., Liu, F."Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report". Experimental and Therapeutic Medicine 11.5 (2016): 1871-1874.
Chicago
Zhu, X., Liu, H., Yuan, S., Xu, X., Dong, Z., Liu, F."Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report". Experimental and Therapeutic Medicine 11, no. 5 (2016): 1871-1874. https://doi.org/10.3892/etm.2016.3161