Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report

Zhu,Xuejing; Liu,Hong; Yuan,Shuguang; Xu,Xiangqing; Dong,Zhen; Liu,Fuyou

doi:10.3892/etm.2016.3161

May-2016 Volume 11 Issue 5

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May-2016 Volume 11 Issue 5

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Case Report

Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report

Authors:
- Xuejing Zhu
- Hong Liu
- Shuguang Yuan
- Xiangqing Xu
- Zhen Dong
- Fuyou Liu
View Affiliations / Copyright

Affiliations: Department of Nephrology, Kidney Institute, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China
Pages: 1871-1874
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Published online on: March 15, 2016

https://doi.org/10.3892/etm.2016.3161
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Abstract

A 38-year-old Chinese man was admitted to the Second Xiangya Hospital of the Central South University (Changsha, China) with heavy proteinuria and rapidly progressing renal failure with nephrotic syndrome. An initial renal biopsy identified collapsing glomerulopathy (CG) with characteristic segmental collapse of the glomerular tuft and marked hypertrophy and hyperplasia of the visceral epithelial cells. A second renal biopsy showed dilation of glomerular capillary loops as a result of effective treatment with rapamycin and anti‑viral therapy. Serology for the coxsackie virus antibody was positive when the collapsing lesion was present, and became negative following treatment, which indicated a strong association between the development of CG and coxsackie virus infection. To the best of our knowledge, this is the first case report of CG associated with coxsackie virus infection.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Collapsing glomerulopathy with rare associated coxsackie virus infection: A case report

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