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Case Report Open Access

Specific clinical manifestations of Nocardia: A case report and literature review

  • Authors:
    • Songsong Yu
    • Jing Wang
    • Qiuhong Fang
    • Jixin Zhang
    • Fengcai Yan
  • View Affiliations / Copyright

    Affiliations: Emergency Department, Beijing Shijitan Hospital, Capital Medical University, Haidian, Beijing 100038, P.R. China, Pulmonary and Critical Care Department, Beijing Chaoyang Hospital, Capital Medical University, Shijingshan, Beijing 100043, P.R. China, Pathology Department, Peking University First Hospital, Xicheng, Beijing 100034, P.R. China, Pathology Department, Beijing Shijitan Hospital, Capital Medical University, Haidian, Beijing 100038, P.R. China
    Copyright: © Yu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2021-2026
    |
    Published online on: August 4, 2016
       https://doi.org/10.3892/etm.2016.3571
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Abstract

Nocardiosis is a rare bacterial infection of either the lungs (pulmonary) or body (systemic) that usually affects immunocompromised individuals. It is caused by Gram‑positive, aerobic actinomycetes of the Nocardia genus. Multiple high‑density sheet shadows in both lungs along with nodules or cavities are the most common presentations of nocardiosis, whereas a large pulmonary mass is considered to be rare. However, there is no specificity in the clinical manifestation of the disease. Therefore, isolation and identification of Nocardia strains is the only reliable diagnostic method. The present study describes the cases of two male patients of Asian descent with nocardiosis. Chest computed tomography scans showed a suspected tumor mass in both patients. Microscopic analysis and culturing of tissue samples obtained using a bronchoscope detected the presence of Nocardia wallacei. Neither patient showed signs of immunosuppression. The present study aimed to improve the understanding of lung nocardiosis and demonstrated that pulmonary nocardiosis should be suspected in the case of non‑immunocompromised patients with a large mass in the lung. Furthermore, a review of the literature on infection with Nocardia was conducted.
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Copy and paste a formatted citation
Spandidos Publications style
Yu S, Wang J, Fang Q, Zhang J and Yan F: Specific clinical manifestations of Nocardia: A case report and literature review. Exp Ther Med 12: 2021-2026, 2016.
APA
Yu, S., Wang, J., Fang, Q., Zhang, J., & Yan, F. (2016). Specific clinical manifestations of Nocardia: A case report and literature review. Experimental and Therapeutic Medicine, 12, 2021-2026. https://doi.org/10.3892/etm.2016.3571
MLA
Yu, S., Wang, J., Fang, Q., Zhang, J., Yan, F."Specific clinical manifestations of Nocardia: A case report and literature review". Experimental and Therapeutic Medicine 12.4 (2016): 2021-2026.
Chicago
Yu, S., Wang, J., Fang, Q., Zhang, J., Yan, F."Specific clinical manifestations of Nocardia: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 4 (2016): 2021-2026. https://doi.org/10.3892/etm.2016.3571
Copy and paste a formatted citation
x
Spandidos Publications style
Yu S, Wang J, Fang Q, Zhang J and Yan F: Specific clinical manifestations of Nocardia: A case report and literature review. Exp Ther Med 12: 2021-2026, 2016.
APA
Yu, S., Wang, J., Fang, Q., Zhang, J., & Yan, F. (2016). Specific clinical manifestations of Nocardia: A case report and literature review. Experimental and Therapeutic Medicine, 12, 2021-2026. https://doi.org/10.3892/etm.2016.3571
MLA
Yu, S., Wang, J., Fang, Q., Zhang, J., Yan, F."Specific clinical manifestations of Nocardia: A case report and literature review". Experimental and Therapeutic Medicine 12.4 (2016): 2021-2026.
Chicago
Yu, S., Wang, J., Fang, Q., Zhang, J., Yan, F."Specific clinical manifestations of Nocardia: A case report and literature review". Experimental and Therapeutic Medicine 12, no. 4 (2016): 2021-2026. https://doi.org/10.3892/etm.2016.3571
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