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Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China

  • Authors:
    • Yanhong Wang
    • Min Shen
    • Jingni Yang
    • Min Dai
    • Yaowen Chang
    • Chi Zhang
    • Guangxin Luan
    • Baodong Ling
    • Xu Jia
  • View Affiliations / Copyright

    Affiliations: Non‑Coding RNA and Drug Discovery Laboratory, Chengdu Medical College, Chengdu, Sichuan 610500, P.R. China, School of Laboratory Medicine, Chengdu Medical College, Chengdu, Sichuan 610500, P.R. China, Small Molecule Drugs Sichuan Key Laboratory, Institute of Materia Medica, Chengdu Medical College, Chengdu, Sichuan 610500, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 3642-3652
    |
    Published online on: October 20, 2016
       https://doi.org/10.3892/etm.2016.3828
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Abstract

The prevalence of aminoglycoside resistant enzymes has previously been reported and extended-spectrum β-lactamase among Acinetobacter baumannii. To track the risk of multidrug‑resistant A. baumannii, the present study aimed to determine the prevalence of carbapenemases in high‑level aminoglycoside resistant A. baumannii over two years. A total of 118 strains of A. baumannii were consecutively collected in the First Affiliated Hospital of Chengdu Medical College, Chengdu, China. These isolates were investigated on the genetic basis of their resistance to aminoglycosides. The results showed that 75 (63.56%) isolates were high‑level resistant to aminoglycosides, including gentamicin and amikacin (minimum inhibitory concentration, ≥256 µg/ml). Aminoglycoside‑resistant genes ant(2
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Copy and paste a formatted citation
Spandidos Publications style
Wang Y, Shen M, Yang J, Dai M, Chang Y, Zhang C, Luan G, Ling B and Jia X: Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China. Exp Ther Med 12: 3642-3652, 2016.
APA
Wang, Y., Shen, M., Yang, J., Dai, M., Chang, Y., Zhang, C. ... Jia, X. (2016). Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China. Experimental and Therapeutic Medicine, 12, 3642-3652. https://doi.org/10.3892/etm.2016.3828
MLA
Wang, Y., Shen, M., Yang, J., Dai, M., Chang, Y., Zhang, C., Luan, G., Ling, B., Jia, X."Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China". Experimental and Therapeutic Medicine 12.6 (2016): 3642-3652.
Chicago
Wang, Y., Shen, M., Yang, J., Dai, M., Chang, Y., Zhang, C., Luan, G., Ling, B., Jia, X."Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China". Experimental and Therapeutic Medicine 12, no. 6 (2016): 3642-3652. https://doi.org/10.3892/etm.2016.3828
Copy and paste a formatted citation
x
Spandidos Publications style
Wang Y, Shen M, Yang J, Dai M, Chang Y, Zhang C, Luan G, Ling B and Jia X: Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China. Exp Ther Med 12: 3642-3652, 2016.
APA
Wang, Y., Shen, M., Yang, J., Dai, M., Chang, Y., Zhang, C. ... Jia, X. (2016). Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China. Experimental and Therapeutic Medicine, 12, 3642-3652. https://doi.org/10.3892/etm.2016.3828
MLA
Wang, Y., Shen, M., Yang, J., Dai, M., Chang, Y., Zhang, C., Luan, G., Ling, B., Jia, X."Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China". Experimental and Therapeutic Medicine 12.6 (2016): 3642-3652.
Chicago
Wang, Y., Shen, M., Yang, J., Dai, M., Chang, Y., Zhang, C., Luan, G., Ling, B., Jia, X."Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China". Experimental and Therapeutic Medicine 12, no. 6 (2016): 3642-3652. https://doi.org/10.3892/etm.2016.3828
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