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Article

Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome

  • Authors:
    • Joanna Stafiej
    • Marta Hałas‑Wiśniewska
    • Magdalena Izdebska
    • Maciej Gagat
    • Dariusz Grzanka
    • Alina Grzanka
    • Grażyna Malukiewicz
  • View Affiliations / Copyright

    Affiliations: Department of Ophthalmology, Faculty of Medicine, Nicolaus Copernicus University Collegium Medicum in Bydgoszcz, 85‑094 Bydgoszcz, Poland, Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University Collegium Medicum in Bydgoszcz, 85‑092 Bydgoszcz, Poland, Department of Dermatology, Sexually Transmitted Diseases and Immunodermatology, Faculty of Medicine, Nicolaus Copernicus University Collegium Medicum in Bydgoszcz, 85‑094 Bydgoszcz, Poland
  • Pages: 1057-1063
    |
    Published online on: January 24, 2017
       https://doi.org/10.3892/etm.2017.4085
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Abstract

Pseudoexfoliation syndrome (PEX) is an age‑associated, sight disorder affecting elastic fibers in the eye and visceral organs but its exact etiology remains unknown. The purpose of the current study was to determine the morphology and ultrastructure of lens epithelial cells (LECs), and to use immunohistochemistry to examine localization of microsomal glutathione S‑transferase 1 (MGST1) and clusterin. Anterior lens capsules were obtained from 24 patients (13 PEX and 11 controls) who underwent phacoemulsification. Immunohistochemistry was performed, using antibodies against MGST1 and clusterin, to determine their expression. The morphology and ultrastructure of LECs were evaluated by light and transmission electron microscopy, respectively. The PEX LECs were characterized by significantly lower MGST1 (P=0.0001) and clusterin expression (P=0.0005) compared with the control group patients. PEX LECs were also observed to have significantly increased thickness compared with the control group patients (P=0.0002). The current findings suggest that low MGST1 and clusterin expression levels may be an early clinical indicator of PEX, and that oxidative stress may serve an important role, but that the specific etiology of this disease has yet to be revealed.
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1 

Lindberg JG: Clinical investigations on depigmentation of the pupillary border and translucency of the iris: In cases of senile cataract and in normal eyes in elderly persons. Acta Ophthalmol Suppl. 190:1–96. 1989.PubMed/NCBI

2 

Schlötzer-Schrehardt UM, Koca MR, Naumann GO and Volkholz H: Pseudoexfoliation syndrome. Ocular manifestation of a systemic disorder? Arch Ophthalmol. 110:1752–1756. 1992. View Article : Google Scholar : PubMed/NCBI

3 

Streeten BW, Li ZY, Wallace RN, Eagle RC Jr and Keshgegian AA: Pseudoexfoliative fibrillopathy in visceral organs of a patient with pseudoexfoliation syndrome. Arch Ophthalmol. 110:1757–1762. 1992. View Article : Google Scholar : PubMed/NCBI

4 

Mitchell P, Wang JJ and Smith W: Association of pseudoexfoliation syndrome with increased vascular risk. Am J Ophthalmol. 124:685–687. 1997. View Article : Google Scholar : PubMed/NCBI

5 

Schumacher S, Schlötzer-Schrehardt U, Martus P, Lang W and Naumann GO: Pseudoexfoliation syndrome and aneurysms of the abdominal aorta. Lancet. 357:359–360. 2001. View Article : Google Scholar : PubMed/NCBI

6 

Ritland JS, Egge K, Lydersen S, Juul R and Semb SO: Exfoliative glaucoma and primary open-angle glaucoma: Associations with death causes and comorbidity. Acta Ophthalmol Scand. 82:401–404. 2004. View Article : Google Scholar : PubMed/NCBI

7 

Allingham RR, Loftsdottir M, Gottfredsdottir MS, Thorgeirsson E, Jonasson F, Sverisson T, Hodge WG, Damji KF and Stefánsson E: Pseudoexfoliation syndrome in Icelandic families. Br J Ophthalmol. 85:702–707. 2001. View Article : Google Scholar : PubMed/NCBI

8 

Stafiej J, Malukiewicz G, Lesiewska-Junk H, Rość D and Kaźmierczak K: Endothelial cell markers in patients with pseudoexfoliation syndrome. ScientificWorldJournal. 2012:8639492012. View Article : Google Scholar : PubMed/NCBI

9 

Tarkkanen A: Is exfoliation syndrome a sign of systemic vascular disease? Acta Ophthalmol. 86:832–836. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Arnarsson A, Damji KF, Sverrisson T, Sasaki H and Jonasson F: Pseudoexfoliation in the Reykjavik Eye Study: Prevalence and related ophthalmological variables. Acta Ophthalmol Scand. 85:822–827. 2007. View Article : Google Scholar : PubMed/NCBI

11 

Mitchell P, Wang JJ and Hourihan F: The relationship between glaucoma and pseudoexfoliation: The Blue Mountains Eye Study. Arch Ophthalmol. 117:1319–1324. 1999. View Article : Google Scholar : PubMed/NCBI

12 

Andrikopoulos GK, Mela EK, Georgakopoulos CD, Papadopoulos GE, Damelou AN, Alexopoulos DK and Gartaganis SP: Pseudoexfoliation syndrome prevalence in Greek patients with cataract and its association to glaucoma and coronary artery disease. Eye(Lond). 23:442–447. 2009.PubMed/NCBI

13 

Forsius H: Exfoliation syndrome in various ethnic populations. Acta Ophthalmol Suppl. 184:71–85. 1988.PubMed/NCBI

14 

Ritch R: Exfoliation syndrome and occludable angles: Trans. Am Ophthalmol Soc. 92:848–855. 1994.

15 

Damji KF, Bains HS, Stafansson E, Loftsdottir M, Sverrisson T, Thorgeirsson E, Jonasson F, Gottfredsdottir M and Allingham RR: Is pseudoexfoliation syndrome inherited? A review of genetic and nongenetic factors and a new obserwation. Ophthalmic Genet. 19:175–185. 1998. View Article : Google Scholar : PubMed/NCBI

16 

Alfaiate M, Leite E, Mira J and Cunha-Vaz JG: Prevalance and surgical complications of pseudoexfoliation syndrome in Portuguese patients with senile cataract. J Cataract Refract Surg. 22:972–976. 1996. View Article : Google Scholar : PubMed/NCBI

17 

Guzek JP, Holm M, Cotter JB, Cameron JA, Rademaker WJ, Wissinger DH, Tonjum AM and Sleeper LA: Risk factors for intraoperative complicatons in 1000 extracapsular cataract cases. Ophthalmology. 94:461–466. 1987. View Article : Google Scholar : PubMed/NCBI

18 

Abbasoğlu OE, Hoşal B, Tekeli O and Gürsel E: Risk factors for vitreous loss in cataract surgery. Eur J Ophthalmol. 10:227–232. 2000.PubMed/NCBI

19 

Drolsum L, Haaskjold E and Davanger M: Pseudoexfoliation syndrome and extracapsular cataract extraction. Acta Ophthalmol (Copenh). 71:765–770. 1993. View Article : Google Scholar : PubMed/NCBI

20 

Lumme P and Laatikainen L: Exfoliation syndrome and cataract extraction. Am J Ophthalmol. 116:51–55. 1993. View Article : Google Scholar : PubMed/NCBI

21 

Hyams M, Mathalone N, Herskovitz M, Hod Y, Israeli D and Geyer O: Intraoperative complications of phacoemulsification in eyes with and without pseudoexfoliation. J Cataract Refract Surg. 31:1002–1005. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Küchle M, Viestenz A, Martus P, Händel A, Jünemann A and Naumann GO: Anterior chamber depth and complications during cataract surgery in eyes with pseudoexfoliation syndrome. Am J Ophthalmol. 129:281–285. 2000. View Article : Google Scholar : PubMed/NCBI

23 

Freissler K, Küchle M and Naumann GO: Spontaneous dislocation of the lens in pseudoexfoliation syndrome. Arch Ophthalmol. 113:1095–1096. 1995. View Article : Google Scholar : PubMed/NCBI

24 

Sufi AR, Singh T, Mufti AA and Rather MH: Outcome of Phacoemulsification in patients with and without Pseudoexfoliation syndrome in Kashmir. BMC Ophthalmol. 12:132012. View Article : Google Scholar : PubMed/NCBI

25 

Ascaso FJ, Huerva V and Grzybowski A: Epidemiology, etiology, and prevention of late IOL-capsular bag complex dislocation: Review of the literature. J Ophthalmol. 2015:8057062015. View Article : Google Scholar : PubMed/NCBI

26 

Guo S, Gewirtz M, Thaker R and Reed M: Characterizing pseudoexfoliation syndrome through the use of ultrasound biomicroscopy. J Cataract Refract Surg. 32:614–617. 2006. View Article : Google Scholar : PubMed/NCBI

27 

Ünsal E, Eltutar K, Muftuoglu I, Akcetin TA and Acar Y: Ultrasound biomicroscopy in patients with unilateral pseudoexfoliation. Int J Ophthalmol. 8:754–758. 2015.PubMed/NCBI

28 

Johnson M: What controls aqueous humour outflow resistance. Exp Eye Res. 82:545–557. 2006. View Article : Google Scholar : PubMed/NCBI

29 

Barbosa AM, Frare AB, Costa NB, Silva RE and Moura KK: GSTM1 polymorphism in patients with primary open-angle glaucoma. Genet Mol Res. 11:3256–3262. 2012. View Article : Google Scholar : PubMed/NCBI

30 

Zenkel M, Lewczuk P, Jünemann A, Kruse FE, Naumann GO and Schlötzer-Schrehardt U: Proinflammatory cytokines are involved in the initiation of the abnormal matrix process in pseudoexfoliation syndrome/glaucoma. Am J Pathol. 176:2868–2879. 2010. View Article : Google Scholar : PubMed/NCBI

31 

Tanito M, Kaidzu S, Takai Y and Ohira A: Status of Systemic oxidative stresses in patients with primary open-angle glaucoma and pseudoexfoliation syndrome. PLoS One. 7:e496802012. View Article : Google Scholar : PubMed/NCBI

32 

Burdon KP, Sharma S, Hewitt AW, McMellon AE, Wang JJ, Mackey DA, Mitchell P and Craig JE: Genetic analysis of the clusterin gene in pseudoexfoliation syndrome. Mol Vis. 14:1727–1736. 2008.PubMed/NCBI

33 

Schlötzer-Schrehardt U: Molecular pathology of pseudoexfoliation syndrome/glaucoma-new insights from LOXL1 gene associations. Exp Eye Res. 88:776–785. 2009. View Article : Google Scholar : PubMed/NCBI

34 

Elhawy E, Kamthan G, Dong CQ and Danias J: Pseudoexfoliation syndrome, a systemic disorder with ocular manifestations. Hum Genomics. 6:222012. View Article : Google Scholar : PubMed/NCBI

35 

Schlötzer-Schrehardt U: Genetics and Genomics of Pseudoexfoliation Syndrome/Glaucoma. Middle East Afr J Ophthalmol. 18:30–36. 2011. View Article : Google Scholar : PubMed/NCBI

36 

Schlötzer-Schrehardt UM, Koca MR, Naumann GO and Volkholz H: Pseudoexfoliation syndrome. Ocular manifestation of a systemic disorder? Arch Ophthalmol. 110:1752–1756. 1992. View Article : Google Scholar : PubMed/NCBI

37 

Comhair SA and Erzurum SC: Redox control of asthma: Molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal. 12:93–124. 2010. View Article : Google Scholar : PubMed/NCBI

38 

Yildirim Z, Ucgun NI and Yildirim F: The role of oxidative stress and antioxidants in the pathogenesis of age-related macular degeneration. Clinics (Sao Paulo). 66:743–746. 2011.PubMed/NCBI

39 

Lobo V, Patil A, Phatak A and Chandra N: Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev. 4:118–126. 2010. View Article : Google Scholar : PubMed/NCBI

40 

Sies H: Total antioxidant capacity: Appraisal of a concept. J Nutr. 137:1493–1495. 2007.PubMed/NCBI

41 

Strzalka-Mrozik B, Prudlo L, Kimsa MW, Kimsa MC, Kapral M, Nita M and Mazurek U: Quantitative analysis of SOD2, ALDH1A1 and MGST1 messenger ribonucleic acid in anterior lens epithelium of patients with pseudoexfoliation syndrome. Mol Vis. 19:1341–1349. 2013.PubMed/NCBI

42 

Zenkel M, Kruse FE, Naumann GO and Schlötzer-Schrehardt U: Impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma. Invest Ophthalmol Vis Sci. 48:5558–5566. 2007. View Article : Google Scholar : PubMed/NCBI

43 

Schlötzer-Schrehardt U: Oxidative stress and pseudoexfoliation glaucoma. Klin Monbl Augenheilkd. 227:108–113. 2010. View Article : Google Scholar : PubMed/NCBI

44 

Zenkel M, Kruse FE, Jünemann AG, Naumann GO and Schlötzer-Schrehardt U: Clusterin deficiency in eyes with pseudoexfoliation syndrome may be implicated in the aggregation and deposition of pseudoexfoliative material. Invest Ophthalmol Vis Sci. 47:1982–1990. 2006. View Article : Google Scholar : PubMed/NCBI

45 

Maggio M, Guralnik JM, Longo DL and Ferrucci L: Interleukin-6 in aging and chronic disease: A magnificent pathway. J Gerontol Biol Sci Med Sci. 61:575–584. 2006. View Article : Google Scholar

46 

Calero M, Rostagno A, Frangione B and Ghiso J: Clusterin and Alzheimer's disease. Subcell Biochem. 38:273–298. 2005. View Article : Google Scholar : PubMed/NCBI

47 

Danysh BP and Duncan MK: The Lens Capsule. Exp Eye Res. 88:151–164. 2009. View Article : Google Scholar : PubMed/NCBI

48 

Krag S and Andreassen TT: Mechanical properties of the human lens capsule. Prog Retin Eye Res. 22:749–767. 2003. View Article : Google Scholar : PubMed/NCBI

49 

Zenkel M and Schlötzer-Schrehardt U: The composition of exfoliation material and the cells involved in its production. J Glaucoma. 23(8): Suppl 1. S12–S14. 2014. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Stafiej J, Hałas‑Wiśniewska M, Izdebska M, Gagat M, Grzanka D, Grzanka A and Malukiewicz G: Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome. Exp Ther Med 13: 1057-1063, 2017.
APA
Stafiej, J., Hałas‑Wiśniewska, M., Izdebska, M., Gagat, M., Grzanka, D., Grzanka, A., & Malukiewicz, G. (2017). Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome. Experimental and Therapeutic Medicine, 13, 1057-1063. https://doi.org/10.3892/etm.2017.4085
MLA
Stafiej, J., Hałas‑Wiśniewska, M., Izdebska, M., Gagat, M., Grzanka, D., Grzanka, A., Malukiewicz, G."Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome". Experimental and Therapeutic Medicine 13.3 (2017): 1057-1063.
Chicago
Stafiej, J., Hałas‑Wiśniewska, M., Izdebska, M., Gagat, M., Grzanka, D., Grzanka, A., Malukiewicz, G."Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome". Experimental and Therapeutic Medicine 13, no. 3 (2017): 1057-1063. https://doi.org/10.3892/etm.2017.4085
Copy and paste a formatted citation
x
Spandidos Publications style
Stafiej J, Hałas‑Wiśniewska M, Izdebska M, Gagat M, Grzanka D, Grzanka A and Malukiewicz G: Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome. Exp Ther Med 13: 1057-1063, 2017.
APA
Stafiej, J., Hałas‑Wiśniewska, M., Izdebska, M., Gagat, M., Grzanka, D., Grzanka, A., & Malukiewicz, G. (2017). Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome. Experimental and Therapeutic Medicine, 13, 1057-1063. https://doi.org/10.3892/etm.2017.4085
MLA
Stafiej, J., Hałas‑Wiśniewska, M., Izdebska, M., Gagat, M., Grzanka, D., Grzanka, A., Malukiewicz, G."Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome". Experimental and Therapeutic Medicine 13.3 (2017): 1057-1063.
Chicago
Stafiej, J., Hałas‑Wiśniewska, M., Izdebska, M., Gagat, M., Grzanka, D., Grzanka, A., Malukiewicz, G."Immunohistochemical analysis of microsomal glutathione S‑transferase 1 and clusterin expression in lens epithelial cells of patients with pseudoexfoliation syndrome". Experimental and Therapeutic Medicine 13, no. 3 (2017): 1057-1063. https://doi.org/10.3892/etm.2017.4085
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