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Article

Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis

  • Authors:
    • Huiqin Liu
    • Wenli Mei
    • Yue Huang
    • Yongli Li
    • Zuzhi Chen
    • Dongdong Li
    • Hong Ye
    • Jiewen Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Neurology, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China, Department of Radiology, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, P.R. China, Department of Neurology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan 453100, P.R. China
  • Pages: 5207-5213
    |
    Published online on: September 22, 2017
       https://doi.org/10.3892/etm.2017.5195
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Abstract

The location and length of the susceptibility vessel sign (SVS) predicts poor outcome for patients having received reperfusion therapy. The aim of the present study was to assess the predictive value of SVS regarding the clinical outcome for patients untreated with thrombolysis. A retrospective study on acute stroke patients who underwent multimodal magnetic resonance imaging within 3 days from the onset of symptoms was performed. None of the patients had received thrombolysis therapy. The presence, location and length of the SVS were assessed. Uni‑ and multivariate analyses were used to examine the association between SVS and clinical outcome. A total of 43 SVS+ and 73 SVS‑ patients were included in the study. A modified Rankin Scale (mRS) of ≤2 at 3 months was determined in 41.9% of patients in the SVS+ group and 79.4% in the SVS‑ group (P<0.001). Multivariate analysis revealed that the presence of SVS was an independent parameter to predict mRS >2 at 3 months (odds ratio, 3.390; 95% confidence interval, 1.122‑10.240; P=0.030). For patients with SVS+ status, the location and length of the SVS were not independent predictors of the clinical outcome. In conclusion, the presence of SVS may predict poor clinical outcome for acute stroke patients untreated with thrombolysis.
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Copy and paste a formatted citation
Spandidos Publications style
Liu H, Mei W, Huang Y, Li Y, Chen Z, Li D, Ye H and Zhang J: Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis. Exp Ther Med 14: 5207-5213, 2017.
APA
Liu, H., Mei, W., Huang, Y., Li, Y., Chen, Z., Li, D. ... Zhang, J. (2017). Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis. Experimental and Therapeutic Medicine, 14, 5207-5213. https://doi.org/10.3892/etm.2017.5195
MLA
Liu, H., Mei, W., Huang, Y., Li, Y., Chen, Z., Li, D., Ye, H., Zhang, J."Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis". Experimental and Therapeutic Medicine 14.5 (2017): 5207-5213.
Chicago
Liu, H., Mei, W., Huang, Y., Li, Y., Chen, Z., Li, D., Ye, H., Zhang, J."Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis". Experimental and Therapeutic Medicine 14, no. 5 (2017): 5207-5213. https://doi.org/10.3892/etm.2017.5195
Copy and paste a formatted citation
x
Spandidos Publications style
Liu H, Mei W, Huang Y, Li Y, Chen Z, Li D, Ye H and Zhang J: Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis. Exp Ther Med 14: 5207-5213, 2017.
APA
Liu, H., Mei, W., Huang, Y., Li, Y., Chen, Z., Li, D. ... Zhang, J. (2017). Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis. Experimental and Therapeutic Medicine, 14, 5207-5213. https://doi.org/10.3892/etm.2017.5195
MLA
Liu, H., Mei, W., Huang, Y., Li, Y., Chen, Z., Li, D., Ye, H., Zhang, J."Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis". Experimental and Therapeutic Medicine 14.5 (2017): 5207-5213.
Chicago
Liu, H., Mei, W., Huang, Y., Li, Y., Chen, Z., Li, D., Ye, H., Zhang, J."Susceptibility vessel sign predicts poor clinical outcome for acute stroke patients untreated by thrombolysis". Experimental and Therapeutic Medicine 14, no. 5 (2017): 5207-5213. https://doi.org/10.3892/etm.2017.5195
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