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Effects of Bambusa tulda on the proliferation of human stem cells

  • Authors:
    • Hyunjin Lee
    • Mohammad Salah Uddin
    • Sang Woo Lee
    • Sangho Choi
    • Jun‑Beom Park
  • View Affiliations / Copyright

    Affiliations: Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea, Ethnobotanical Database of Bangladesh, Dhaka 1208, People's Republic of Bangladesh, International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea
    Copyright: © Lee et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 5696-5702
    |
    Published online on: October 10, 2017
       https://doi.org/10.3892/etm.2017.5276
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Abstract

To date, the effects of Bambusa tulda on stem cells have not been thoroughly assessed. The present study aimed to evaluate the effects of Bambusa tulda extract on the morphology and proliferative potential of human mesenchymal stem cells derived from the gingiva. The stem cells were cultured in a growth medium in the presence of Bambusa tulda methanolic extract (BBT) at concentrations ranging from 0.001 to 1%. Evaluation of cell morphology and cellular proliferation as well as immunofluorescent assays for collagen I were performed on days 1, 3, 5 and 7. Stem cells in the control group displayed a fibroblast‑like morphology, and BBT treatment did not produce any noticeable morphological changes. However, application of 1% BBT produced a significant increase in cell proliferation. BBT, particularly at the concentration of 1%, also caused a noticeable increase of collagen I expression at day 1 and day 3. Based on these findings, it was concluded that BBT exerted beneficial effects on the proliferation of mesenchymal stem cells and enhanced collagen I expression at early time points.
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Copy and paste a formatted citation
Spandidos Publications style
Lee H, Uddin MS, Lee SW, Choi S and Park JB: Effects of Bambusa tulda on the proliferation of human stem cells. Exp Ther Med 14: 5696-5702, 2017.
APA
Lee, H., Uddin, M.S., Lee, S.W., Choi, S., & Park, J. (2017). Effects of Bambusa tulda on the proliferation of human stem cells. Experimental and Therapeutic Medicine, 14, 5696-5702. https://doi.org/10.3892/etm.2017.5276
MLA
Lee, H., Uddin, M. S., Lee, S. W., Choi, S., Park, J."Effects of Bambusa tulda on the proliferation of human stem cells". Experimental and Therapeutic Medicine 14.6 (2017): 5696-5702.
Chicago
Lee, H., Uddin, M. S., Lee, S. W., Choi, S., Park, J."Effects of Bambusa tulda on the proliferation of human stem cells". Experimental and Therapeutic Medicine 14, no. 6 (2017): 5696-5702. https://doi.org/10.3892/etm.2017.5276
Copy and paste a formatted citation
x
Spandidos Publications style
Lee H, Uddin MS, Lee SW, Choi S and Park JB: Effects of Bambusa tulda on the proliferation of human stem cells. Exp Ther Med 14: 5696-5702, 2017.
APA
Lee, H., Uddin, M.S., Lee, S.W., Choi, S., & Park, J. (2017). Effects of Bambusa tulda on the proliferation of human stem cells. Experimental and Therapeutic Medicine, 14, 5696-5702. https://doi.org/10.3892/etm.2017.5276
MLA
Lee, H., Uddin, M. S., Lee, S. W., Choi, S., Park, J."Effects of Bambusa tulda on the proliferation of human stem cells". Experimental and Therapeutic Medicine 14.6 (2017): 5696-5702.
Chicago
Lee, H., Uddin, M. S., Lee, S. W., Choi, S., Park, J."Effects of Bambusa tulda on the proliferation of human stem cells". Experimental and Therapeutic Medicine 14, no. 6 (2017): 5696-5702. https://doi.org/10.3892/etm.2017.5276
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