Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
April-2018 Volume 15 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April-2018 Volume 15 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review

  • Authors:
    • Dexin Zou
    • Junlin Zhou
    • Xiaobing Jiang
  • View Affiliations / Copyright

    Affiliations: Department of Orthopaedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. China, Department of Equipment, Yantai Yuhuangdi Hospital, Yantai, Shandong 264000, P.R. China
  • Pages: 3455-3458
    |
    Published online on: January 30, 2018
       https://doi.org/10.3892/etm.2018.5812
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Tuberculosis combined with brucellosis is a very rare condition. Overlapping clinical presentation and laboratory parameters of tuberculosis and brucellosis may lead to misdiagnosis or delayed diagnosis of the condition. The current study presents the case of a 45‑year‑old male with symptoms of lower back pain, non‑tender swelling in the right flank, intermittent hyperpyrexia, sweating, body aches and numbness and weakness of right lower limb. A lumbar computed tomograph (CT) scan and magnetic resonance imaging indicated vertebral destruction and the formation of sequestra and thecal sac compression. Tuberculosis was suspected, but subsequent culture of blood and pus revealed the co‑infection of Mycobacterium tuberculosis and Brucella melitensis. The patient was treated with antibiotics, CT‑guided percutaneous drainage of the abscess and posterior approach decompression, debridement, instrumentation and fusion. Co‑existence of spinal tuberculosis and brucellosis is rare and clinicians should strengthen the awareness of such conditions in similar patients. CT‑guided percutaneous drainage is effective in the diagnosis and management of spinal tuberculosis with abscess.
View Figures

Figure 1

Figure 2

View References

1 

Metha JS and Bhojraj SY: Tuberculosis of the thoracic spine. J Bone Joint Surg Br. 85:1502003.PubMed/NCBI

2 

World Health Organization, . Global tuberculosis report 2012. WHO; Geneva: 2012

3 

Samohyl M, Solovic I, Rams R, Hirosova K, Vondrova D, Krajcova D, Nadazdyova A, Filova A and Jurkovicova J: Effect of spa treatment and the epidemiology of tuberculosis in the Slovak republic in the year 2014. Clin Soc Work Health Interven. 7:24–35. 2016. View Article : Google Scholar

4 

Cui X, Ma YZ, Chen X, Cai XJ, Li HW and Bai YB: Outcomes of different surgical procedures in the treatment of spinal tuberculosis in adults. Med Princ Pract. 22:346–350. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Saraf SK and Tuli SM: Tuberculosis of hip: A current concept review. Indian J Orthop. 49:1–9. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Fuentes Ferrer M, Gutiérrez Torres L, Ayala Ramírez O, Rumayor Zarzuelo M and del Prado González N: Tuberculosis of the spine. A systematic review of case series. Int Orthop. 36:221–231. 2012. View Article : Google Scholar : PubMed/NCBI

7 

Moon MS: Tuberculosis of spine: Current views in diagnosis and management. Asian Spine J. 8:97–111. 2014. View Article : Google Scholar : PubMed/NCBI

8 

Polley P and Dunn R: Noncontiguous spinal tuberculosis: Incidence and management. Eur Spine J. 18:1096–1101. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Pawlowski A, Jansson M, Sköld M, Rottenberg ME and Källenius G: Tuberculosis and HIV co-infection. PLoS Pathog. 8:e10024642012. View Article : Google Scholar : PubMed/NCBI

10 

Franco MP, Mulder M, Gilman RH and Smits HL: Human brucellosis. Lancet Infect Dis. 7:775–786. 2007. View Article : Google Scholar : PubMed/NCBI

11 

Turgut M, Haddad FS and De Divitiis O: Neurobrucellosis: Clinical, diagnostic and therapeutic features. BMJ. 333:152015.

12 

Hadush A and Pal M: Brucellosis-An infectious re-emerging bacterial zoonosis of global importance. Int J Livest Res. 3:28–34. 2013. View Article : Google Scholar

13 

Frankel HL, Hancock DO, Hyslop G, Melzak J, Michaelis LS, Ungar GH, Vernon JD and Walsh JJ: The value of postural reduction in the initial management of closed injuries of the spine with paraplegia and tetraplegia. I. Paraplegia. 7:179–192. 1969.PubMed/NCBI

14 

Seibert FB and Dufour EH: Comparison between the international standard tuberculins, PPD-S and old tuberculin. Am Rev Tuberc. 69:585–594. 1954.PubMed/NCBI

15 

Bai Y, Han X, Wu J, Chen Z and Li L: Ecosystem stability and compensatory effects in the inner mongolia grassland. Nature. 431:181–184. 2004. View Article : Google Scholar : PubMed/NCBI

16 

Rose JE and Roepke MH: An acidified antigen for detection of nonspecific reactions in the plate-agglutination test for bovine brucellosis. Am J Vet Res. 18:550–555. 1957.PubMed/NCBI

17 

Alton GG, Maw J, Rogerson BA and Mcpherson GG: The serological diagnosis of bovine brucellosis: An evaluation of the complement fixation, serum agglutination and rose bengal tests. Aust Vet J. 51:57–63. 1975. View Article : Google Scholar : PubMed/NCBI

18 

Dasari S, Naha K and Prabhu M: Brucellosis and tuberculosis: Clinical overlap and pitfalls. Asian Pac J Trop Med. 6:823–825. 2013. View Article : Google Scholar : PubMed/NCBI

19 

Kurtaran B, Sarpel T, Tasova Y, Candevir A, Saltoglu N, Inal AS and Aksu HSZ: Brucellar and tuberculous spondylitis in 87 adult patients: A descriptive and comparative case series. Infect Dis Clin Prac. 16:166–173. 2008. View Article : Google Scholar

20 

Dal T, Celen MK, Ayaz C, Dal MS, Kalkanli S, Mert D, Yildirim N, Aktas E and Arserim N: Brucellosis is a major problem: A five years experience. Acta Med Mediterr. 29:6652013.

21 

Pappas G, Akritidis N, Bosilkovski M and Tsianos E: Brucellosis. N Engl J Med. 352:2325–2336. 2005. View Article : Google Scholar : PubMed/NCBI

22 

Zhong Z, Yu S, Wang X, Dong S, Xu J, Wang Y, Chen Z, Ren Z and Peng G: Human brucellosis in the People's Republic of China during 2005–2010. Int J Infect Dis. 17:e289–e292. 2013. View Article : Google Scholar : PubMed/NCBI

23 

Yilmaz E, Parlak M, Akalin H, Heper Y, Ozakin C, Mistik R, Oral B, Helvaci S and Töre O: Brucellar spondylitis: Review of 25 cases. J Clin Rheumatol Pract Rep Dis. 10:300–307. 2004. View Article : Google Scholar

24 

Ansari S, Ashraf AN, Najib A, Moutaery and Al K: Spinal infections: A review. Neuro Quart. 11:112–123. 2001. View Article : Google Scholar

25 

Alothman A, Memish ZA, Awada A, Al-Mahmood S, Al-Sadoon S, Rahman MM and Khan MY: Tuberculous spondylitis: Analysis of 69 cases from Saudi Arabia. Spine (Phila Pa 1976). 26:E565–E570. 2001. View Article : Google Scholar : PubMed/NCBI

26 

Schaaf HS, Shean K and Donald PR: Culture confirmed multidrug resistant tuberculosis: Diagnostic delay, clinical features, and outcome. Arch Dis Child. 88:1106–1111. 2003. View Article : Google Scholar : PubMed/NCBI

27 

Billard E, Cazevieille C, Dornand J and Gross A: High susceptibility of human dendritic cells to invasion by the intracellular pathogens Brucella suis, B. Abortus, and B. Melitensis. Infect Immun. 73:8418–8424. 2005. View Article : Google Scholar : PubMed/NCBI

28 

Hartady T, Saad MZ, Bejo SK and Salisi MS: Clinical human brucellosis in Malaysia: A case report. Asian Pac J Trop Dis. 4:150–153. 2014. View Article : Google Scholar

29 

Human brucellosis: Systematic review and meta-analysis of randomised controlled trials. BMJ. 336:7012008. View Article : Google Scholar : PubMed/NCBI

30 

Sundararaj GD, Behera S, Ravi V, Venkatesh K, Cherian VM and Lee V: Role of posterior stabilisation in the management of tuberculosis of the dorsal and lumbar spine. J Bone Joint Surg Br. 85:100–106. 2003. View Article : Google Scholar : PubMed/NCBI

31 

Chen WJ, Wu CC, Jung CH, Chen LH, Niu CC and Lai PL: Combined anterior and posterior surgeries in the treatment of spinal tuberculous spondylitis. Clin Orthop Relat Res. 1–59. 2002.

32 

Liu P, Sun M, Li S, Wang Z and Ding G: A retrospective controlled study of three different operative approaches for the treatment of thoracic and lumbar spinal tuberculosis: Three years of follow-up. Clin Neurol Neurosurg. 128:25–34. 2015. View Article : Google Scholar : PubMed/NCBI

33 

Li J, Li XL, Zhou XG, Zhou J and Dong J: Surgical treatment for spinal tuberculosis with bilateral paraspinal abscess or bilateral psoas abscess: One-stage surgery. J Spinal Disord Tech. 27:E309–E314. 2014. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zou D, Zhou J and Jiang X: Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review. Exp Ther Med 15: 3455-3458, 2018.
APA
Zou, D., Zhou, J., & Jiang, X. (2018). Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review. Experimental and Therapeutic Medicine, 15, 3455-3458. https://doi.org/10.3892/etm.2018.5812
MLA
Zou, D., Zhou, J., Jiang, X."Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review". Experimental and Therapeutic Medicine 15.4 (2018): 3455-3458.
Chicago
Zou, D., Zhou, J., Jiang, X."Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review". Experimental and Therapeutic Medicine 15, no. 4 (2018): 3455-3458. https://doi.org/10.3892/etm.2018.5812
Copy and paste a formatted citation
x
Spandidos Publications style
Zou D, Zhou J and Jiang X: Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review. Exp Ther Med 15: 3455-3458, 2018.
APA
Zou, D., Zhou, J., & Jiang, X. (2018). Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review. Experimental and Therapeutic Medicine, 15, 3455-3458. https://doi.org/10.3892/etm.2018.5812
MLA
Zou, D., Zhou, J., Jiang, X."Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review". Experimental and Therapeutic Medicine 15.4 (2018): 3455-3458.
Chicago
Zou, D., Zhou, J., Jiang, X."Diagnosis and management of spinal tuberculosis combined with brucellosis: A case report and literature review". Experimental and Therapeutic Medicine 15, no. 4 (2018): 3455-3458. https://doi.org/10.3892/etm.2018.5812
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team