|
1
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2015. CA Cancer J Clin. 65:5–29. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Endogenous Hormones and Breast Cancer
Collaborative Group; Key TJ, Appleby PN, Reeves GK, Travis RC,
Alberg AJ, Barricarte A, Berrino F, Krogh V, Sieri S, et al: Sex
hormones and risk of breast cancer in premenopausal women: A
collaborative reanalysis of individual participant data from seven
prospective studies. Lancet Oncol. 14:1009–1019. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Couch FJ, Hart SN, Sharma P, Toland AE,
Wang X, Miron P, Olson JE, Godwin AK, Pankratz VS, Olswold C, et
al: Inherited mutations in 17 breast cancer susceptibility genes
among a large triple-negative breast cancer cohort unselected for
family history of breast cancer. J Clin Oncol. 33:304–311. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Deryugina EI and Quigley JP: Tumor
angiogenesis: MMP-mediated induction of intravasation- and
metastasis-sustaining neovasculature. Matrix Biol. 44–46:94–112.
2015. View Article : Google Scholar
|
|
5
|
Richert MM, Vaidya KS, Mills CN, Wong D,
Korz W, Hurst DR and Welch DR: Inhibition of CXCR4 by CTCE-9908
inhibits breast cancer metastasis to lung and bone. Oncol Rep.
21:761–767. 2009.PubMed/NCBI
|
|
6
|
Bono F, de Smet F, Herbert C, de Bock K,
Georgiadou M, Fons P, Tjwa M, Alcouffe C, Ny A, Bianciotto M, et
al: Inhibition of tumor angiogenesis and growth by a small-molecule
multi-FGF receptor blocker with allosteric properties. Cancer Cell.
23:477–488. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Seftor RE, Hess AR, Seftor EA, Kirschmann
DA, Hardy KM, Margaryan NV and Hendrix MJ: Tumor cell vasculogenic
mimicry: From controversy to therapeutic promise. Am J Pathol.
181:1115–1125. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Zhou J, Xi C, Wang W, Fu X, Jinqiang L,
Qiu Y, Jin J, Xu J and Huang Z: Triptolide-induced oxidative stress
involved with Nrf2 contribute to cardiomyocyte apoptosis through
mitochondrial dependent pathways. Toxicol Lett. 230:454–466. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Liu J, Jiang Z, Xiao J, Zhang Y, Lin S,
Duan W, Yao J, Liu C, Huang X, Wang T, et al: Effects of triptolide
from Tripterygium wilfordii on ERalpha and p53 expression in two
human breast cancer cell lines. Phytomedicine. 16:1006–1013. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Pigneux A, Mahon FX, Uhalde M, Jeanneteau
M, Lacombe F, Milpied N, Reiffers J and Belloc F: Triptolide
cooperates with chemotherapy to induce apoptosis in acute myeloid
leukemia cells. Exp Hematol. 36:1648–1659. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Park SW and Kim YI: Triptolide induces
apoptosis of PMA-treated THP-1 cells through activation of
caspases, inhibition of NF-κB and activation of MAPKs. Int J Oncol.
43:1169–1175. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Chen F, Gao X and Shilatifard A: Stably
paused genes revealed through inhibition of transcription
initiation by the TFIIH inhibitor triptolide. Genes Dev. 29:39–47.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Owa C, Messina ME Jr and Halaby R:
Triptolide induces lysosomal-mediated programmed cell death in
MCF-7 breast cancer cells. Int J Womens Health. 5:557–569.
2013.PubMed/NCBI
|
|
14
|
Hu C, Huang F, Deng G, Nie W, Huang W and
Zeng X: miR-31 promotes oncogenesis in intrahepatic
cholangiocarcinoma cells via the direct suppression of RASA1. Exp
Ther Med. 6:1265–1270. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Li J, Zhao X, Wang D, He W, Zhang S, Cao
W, Huang Y, Wang L, Zhou S and Luo K: Up-regulated expression of
phospholipase C, β1 is associated with tumor cell proliferation and
poor prognosis in hepatocellular carcinoma. Onco Targets Ther.
9:1697–1706. 2016.PubMed/NCBI
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kong W, He L, Richards EJ, Challa S, Xu
CX, Permuth-Wey J, Lancaster JM, Coppola D, Sellers TA, Djeu JY and
Cheng JQ: Upregulation of miRNA-155 promotes tumour angiogenesis by
targeting VHL and is associated with poor prognosis and
triple-negative breast cancer. Oncogene. 33:679–689. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Shao H, Ma J, Guo T and Hu R: Triptolide
induces apoptosis of breast cancer cells via a mechanism associated
with the Wnt/β-catenin signaling pathway. Exp Ther Med. 8:505–508.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Jiang BH and Liu LZ: PI3K/PTEN signaling
in angiogenesis and tumorigenesis. Adv Cancer Res. 102:19–65. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Qiu D, Zhao G, Aoki Y, Shi L, Uyei A,
Nazarian S, Ng JC and Kao PN: Immunosuppressant PG490 (triptolide)
inhibits T-cell interleukin-2 expression at the level of
purine-box/nuclear factor of activated T-cells and NF-kappaB
transcriptional activation. J Biol Chem. 274:13443–13450. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Chen X, Murakami T, Oppenheim JJ and
Howard OM: Triptolide, a constituent of immunosuppressive Chinese
herbal medicine, is a potent suppressor of dendritic-cell
maturation and trafficking. Blood. 106:2409–2416. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang X, Zhang L, Duan W, Liu B, Gong P,
Ding Y and Wu X: Anti-inflammatory effects of triptolide by
inhibiting the NF-κB signalling pathway in LPS-induced acute lung
injury in a murine model. Mol Med Rep. 10:447–452. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhang H, Gong C, Qu L, Ding X, Cao W, Chen
H, Zhang B and Zhou G: Therapeutic effects of triptolide via the
inhibition of IL-1β expression in a mouse model of ulcerative
colitis. Exp Ther Med. 12:1279–1286. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Yang S, Chen J, Guo Z, Xu XM, Wang L, Pei
XF, Yang J, Underhill CB and Zhang L: Triptolide inhibits the
growth and metastasis of solid tumors. Mol Cancer Ther. 2:65–72.
2003.PubMed/NCBI
|
|
25
|
Koh MS and Moon A: Activation of H-Ras and
Rac1 correlates with epidermal growth factor-induced invasion in
Hs578T and MDA-MB-231 breast carcinoma cells. Biochem Biophys Res
Commun. 406:25–29. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Kim SH, Kang JG, Kim CS, Ihm SH, Choi MG,
Yoo HJ and Lee SJ: Synergistic cytotoxicity of BIIB021 with
triptolide through suppression of PI3K/Akt/mTOR and NF-κB signal
pathways in thyroid carcinoma cells. Biomed Pharmacother. 83:22–32.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhao X, Zhang Q and Chen L: Triptolide
induces the cell apoptosis of osteosarcoma cells through the TRAIL
pathway. Oncol Rep. 36:1499–1505. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Galvez G, Santander S, Raskin I and
Baldeon M: Effects of triptolide on the expression of inflammatory
markers in lipopolysaccharide-treated human endothelial cells
(HUVEC). FASEB J. 29:789–781. 2015.
|
|
29
|
Liu L, Salnikov AV, Bauer N,
Aleksandrowicz E, Labsch S, Nwaeburu C, Mattern J, Gladkich J,
Schemmer P, Werner J and Herr I: Triptolide reverses
hypoxia-induced epithelial-mesenchymal transition and stem-like
features in pancreatic cancer by NF-κB downregulation. Int J
Cancer. 134:2489–2503. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Sarkar TR, Battula VL, Werden SJ, Vijay
GV, Ramirez-Peña EQ, Taube JH, Chang JT, Miura N, Porter W, Sphyris
N, et al: GD3 synthase regulates epithelial-mesenchymal transition
and metastasis in breast cancer. Oncogene. 34:2958–2967. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Huang T, Chen Z and Fang L: Curcumin
inhibits LPS-induced EMT through downregulation of NF-κB-Snail
signaling in breast cancer cells. Oncol Rep. 29:117–124. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Ahluwalia A and Tarnawski AS: Critical
role of hypoxia sensor-HIF-1α in VEGF gene activation. Implications
for angiogenesis and tissue injury healing. Curr Med Chem.
19:90–97. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Ke Q and Costa M: Hypoxia-inducible
factor-1 (HIF-1). Mol Pharmacol. 70:1469–1480. 2006. View Article : Google Scholar : PubMed/NCBI
|
