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Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs

  • Authors:
    • Qiang Zuo
    • Feng Gao
    • Huanghe Song
    • Jinchun Zhou
  • View Affiliations / Copyright

    Affiliations: Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China
    Copyright: © Zuo et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1355-1359
    |
    Published online on: June 18, 2018
       https://doi.org/10.3892/etm.2018.6321
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Abstract

The aim of the present study is to investigate the clinical value of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs. A total of 90 patients with chronic ischemic diseases in lower limbs were selected and randomly divided into two groups: The observation group (n=45) and the control group (n=45). Those patients were treated with Ilizarov transverse tibial bone transport and microcirculation reconstruction, and percutaneous balloon angioplasty (PTBA), respectively. Changes in the diameter, blood flow of lower limb arteries in the paretic side, wound healing time, disappearance time of pains, dorsal foot skin temperature, and the expression area of vascular endothelial growth factors (VEGFs) were detected in both groups. Compared with control group, the diameters and blood flows of lower limb arteries were significantly larger (P<0.05), and the dorsal foot skin temperature was significantly higher at 1 day, 1 week and 1 month after operation, respectively. Meantime, the expression area of VEGFs in the observation group was significantly larger than that in the control group at 1 day, 1 week and 1 month, respectively. Furthermore, compared with control group, wound healing time and disappearance time of pains of patients were earlier in the observation group (P<0.05). At 1 month after operation, the intermittent claudication, rest pain and lower limb ulcer or gangrene among clinical symptoms of patients in the observation group improved significantly more than those in the control group (P<0.05). In conclusion, the application of Ilizarov transverse tibial bone transport and microcirculation reconstruction could achieve better outcomes in the treatment of chronic ischemic diseases in lower limbs.
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Copy and paste a formatted citation
Spandidos Publications style
Zuo Q, Gao F, Song H and Zhou J: Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs. Exp Ther Med 16: 1355-1359, 2018.
APA
Zuo, Q., Gao, F., Song, H., & Zhou, J. (2018). Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs. Experimental and Therapeutic Medicine, 16, 1355-1359. https://doi.org/10.3892/etm.2018.6321
MLA
Zuo, Q., Gao, F., Song, H., Zhou, J."Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs". Experimental and Therapeutic Medicine 16.2 (2018): 1355-1359.
Chicago
Zuo, Q., Gao, F., Song, H., Zhou, J."Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs". Experimental and Therapeutic Medicine 16, no. 2 (2018): 1355-1359. https://doi.org/10.3892/etm.2018.6321
Copy and paste a formatted citation
x
Spandidos Publications style
Zuo Q, Gao F, Song H and Zhou J: Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs. Exp Ther Med 16: 1355-1359, 2018.
APA
Zuo, Q., Gao, F., Song, H., & Zhou, J. (2018). Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs. Experimental and Therapeutic Medicine, 16, 1355-1359. https://doi.org/10.3892/etm.2018.6321
MLA
Zuo, Q., Gao, F., Song, H., Zhou, J."Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs". Experimental and Therapeutic Medicine 16.2 (2018): 1355-1359.
Chicago
Zuo, Q., Gao, F., Song, H., Zhou, J."Application of Ilizarov transverse tibial bone transport and microcirculation reconstruction in the treatment of chronic ischemic diseases in lower limbs". Experimental and Therapeutic Medicine 16, no. 2 (2018): 1355-1359. https://doi.org/10.3892/etm.2018.6321
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