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Correlation analysis of intestinal flora with hypertension

  • Authors:
    • Jilun Liu
    • Ning An
    • Cong Ma
    • Xiaofeng Li
    • Jie Zhang
    • Wei Zhu
    • Yihe Zhang
    • Junpeng Li
  • View Affiliations / Copyright

    Affiliations: Department of Cardiology, No. 215 Hospital of Shaanxi Nuclear Industry, Xianyang, Shaanxi 712000, P.R. China, Department of Cardiology, Xingyuan Hospital of Yulin City, Yulin, Shaanxi 719000, P.R. China, Department of Clinical Medicine, Medical College of Nanchang University, Nanchang, Jiangxi 330031, P.R. China, Department of Clinical Laboratory, Central Hospital of Xi'an City, Xi'an, Shaanxi 710003, P.R. China, Department of Internal Medicine, No. 5 Hospital of Xi'an City, Xi'an, Shaanxi 710082, P.R. China, Department of Clinical Laboratory, Central Hospital of Baoji City, Baoji, Shaanxi 721008, P.R. China, Department of Cardiovascular Medical Center, Dongguan Cardiovascular and Cerebrovascular Disease Hospital, The Affiliated Hospital of Yan'an University, Yan'an, Shaanxi 716000, P.R. China
  • Pages: 2325-2330
    |
    Published online on: July 20, 2018
       https://doi.org/10.3892/etm.2018.6500
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Abstract

Relationship between intestinal flora content and hypertension was investigated. Ninety-four patients with hypertension who were admitted and treated in No. 215 Hospital of Shaanxi Nuclear Industry from May 2016 to April 2017 were selected as the observation group; and 94 healthy people from the physical examination center of No. 215 Hospital of Shaanxi Nuclear Industry in the same time period were selected as the control group. The systolic (SBP) and diastolic blood pressure (DBP) of all the participants were measured. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to detect the quantities of Eubacterium rectale, Bacteroides thetaiotaomicron and Bifidobacterium in the intestines, and correlation analyses were performed. The SBP, DBP and content of Eubacterium rectale in the observation group were significantly higher than those in the control group, while the contents of Bacteroides thetaiotaomicron and Bifidobacterium were obviously lower than those in the control group (P<0.05). Pearson's correlation analysis showed that Eubacterium rectale was positively correlated with SBP and DBP, while Bacteroides thetaiotaomicron and Bifidobacterium had a negative correlation with SBP and DBP (P<0.05). The results showed that the quantities of Bifidobacterium and Bacteroides thetaiotaomicron are decreased while the number of Eubacterium rectale is increased in the intestines of patients with hypertension. Moreover, the content of intestinal flora has a significant correlation with hypertension.
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Copy and paste a formatted citation
Spandidos Publications style
Liu J, An N, Ma C, Li X, Zhang J, Zhu W, Zhang Y and Li J: Correlation analysis of intestinal flora with hypertension. Exp Ther Med 16: 2325-2330, 2018.
APA
Liu, J., An, N., Ma, C., Li, X., Zhang, J., Zhu, W. ... Li, J. (2018). Correlation analysis of intestinal flora with hypertension. Experimental and Therapeutic Medicine, 16, 2325-2330. https://doi.org/10.3892/etm.2018.6500
MLA
Liu, J., An, N., Ma, C., Li, X., Zhang, J., Zhu, W., Zhang, Y., Li, J."Correlation analysis of intestinal flora with hypertension". Experimental and Therapeutic Medicine 16.3 (2018): 2325-2330.
Chicago
Liu, J., An, N., Ma, C., Li, X., Zhang, J., Zhu, W., Zhang, Y., Li, J."Correlation analysis of intestinal flora with hypertension". Experimental and Therapeutic Medicine 16, no. 3 (2018): 2325-2330. https://doi.org/10.3892/etm.2018.6500
Copy and paste a formatted citation
x
Spandidos Publications style
Liu J, An N, Ma C, Li X, Zhang J, Zhu W, Zhang Y and Li J: Correlation analysis of intestinal flora with hypertension. Exp Ther Med 16: 2325-2330, 2018.
APA
Liu, J., An, N., Ma, C., Li, X., Zhang, J., Zhu, W. ... Li, J. (2018). Correlation analysis of intestinal flora with hypertension. Experimental and Therapeutic Medicine, 16, 2325-2330. https://doi.org/10.3892/etm.2018.6500
MLA
Liu, J., An, N., Ma, C., Li, X., Zhang, J., Zhu, W., Zhang, Y., Li, J."Correlation analysis of intestinal flora with hypertension". Experimental and Therapeutic Medicine 16.3 (2018): 2325-2330.
Chicago
Liu, J., An, N., Ma, C., Li, X., Zhang, J., Zhu, W., Zhang, Y., Li, J."Correlation analysis of intestinal flora with hypertension". Experimental and Therapeutic Medicine 16, no. 3 (2018): 2325-2330. https://doi.org/10.3892/etm.2018.6500
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