Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
October-2018 Volume 16 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2018 Volume 16 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin

  • Authors:
    • Jie-Yang Yu
    • Jia-Hua Peng
    • Li Hui
    • Hui-Quan Huang
    • Ming-Hua Tan
    • Guo Jian
  • View Affiliations / Copyright

    Affiliations: Intensive Care Unit, People's Hospital of Baise, Baise, Guangxi Zhuang Autonomous Region 533000, P.R. China
  • Pages: 3534-3538
    |
    Published online on: August 9, 2018
       https://doi.org/10.3892/etm.2018.6591
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The present study was designed to investigate the association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin (HNL). A total of 112 patients confirmed with traumatic hemorrhage were enrolled as study subjects and were randomly divided into the control group (n=56) and observation group (n=56). The control group was treated with rapid fluid resuscitation, and the observation group was treated with controlled fluid resuscitation. The success rate of resuscitation, incidence rate of complications, and HNL levels were compared both before and after resuscitation at multiple time intervals. The success rate of resuscitation showed a significant improvement while the incidence rate of complications were decreased. The HNL levels in both groups revealed increase after resuscitation at 3-10 h, thereby, they showed decline following peak point. However, the peak reduction in the observation group appeared earlier, while the HNL levels at 24 and 72 h were significantly lower than those in the control group. The study concluded that the effect of controlled fluid resuscitation on massive hemorrhage was superior to that of rapid fluid resuscitation. Moreover, controlled fluid resuscitation was also able to decrease the level of HNL as well as inflammatory response.
View Figures

Figure 1

View References

1 

Zhao G, Wu W, Feng QM and Sun J: Evaluation of the clinical effect of small-volume resuscitation on uncontrolled hemorrhagic shock in emergency. Ther Clin Risk Manag. 13:387–392. 2017. View Article : Google Scholar : PubMed/NCBI

2 

Li T, Zhu Y, Tian K, Xue M, Peng X, Lan D and Liu L: Ideal resuscitation pressure for uncontrolled hemorrhagic shock in different ages and sexes of rats. Crit Care. 17:R1942013. View Article : Google Scholar : PubMed/NCBI

3 

Ertmer C, Kampmeier T, Rehberg S and Lange M: Fluid resuscitation in multiple trauma patients. Curr Opin Anaesthesiol. 24:202–208. 2011. View Article : Google Scholar : PubMed/NCBI

4 

Duan C, Li T and Liu L: Efficacy of limited fluid resuscitation in patients with hemorrhagic shock: A meta-analysis. Int J Clin Exp Med. 8:11645–11656. 2015.PubMed/NCBI

5 

Moran A, Thacker SA, Arikan AA, Mastrangelo M-AA, Wu Y, Yu B and Tweardy DJ: IL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammation. PLoS One. 6:e214492011. View Article : Google Scholar : PubMed/NCBI

6 

Liappis AP, Gibbs KW, Nylen ES, Yoon B, Snider RH, Gao B and Becker KL: Exogenous procalcitonin evokes a pro-inflammatory cytokine response. Inflamm Res. 60:203–207. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Wright EH and Khan U: Serum complement-reactive protein (CRP) trends following local and free-tissue reconstructions for traumatic injuries or chronic wounds of the lower limb. J Plast Reconstr Aesthet Surg. 63:1519–1522. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Constantin JM, Futier E, Perbet S, Roszyk L, Lautrette A, Gillart T, Guerin R, Jabaudon M, Souweine B, Bazin J-E, et al: Plasma neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: A prospective study. Crit Care. 25:176.e10–176.e6. 2010.

9 

Cruz DN, de Cal M, Garzotto F, Perazella MA, Lentini P, Corradi V, Piccinni P and Ronco C: Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population. Intensive Care Med. 36:444–451. 2010. View Article : Google Scholar : PubMed/NCBI

10 

Portal AJ, McPhail MJ, Bruce M, Coltart I, Slack A, Sherwood R, Heaton ND, Shawcross D, Wendon JA and Heneghan MA: Neutrophil gelatinase - associated lipocalin predicts acute kidney injury in patients undergoing liver transplantation. Liver Transpl. 16:1257–1266. 2010. View Article : Google Scholar : PubMed/NCBI

11 

de Geus HR, Bakker J, Lesaffre EM and le Noble JL: Neutrophil gelatinase-associated lipocalin at ICU admission predicts for acute kidney injury in adult patients. Am J Respir Crit Care Med. 183:907–914. 2011. View Article : Google Scholar : PubMed/NCBI

12 

Baker SP, O'Neill B, Haddon W Jr and Long WB: The injury severity score: A method for describing patients with multiple injuries and evaluating emergency care. J Trauma. 14:187–196. 1974. View Article : Google Scholar : PubMed/NCBI

13 

Morrison CA, Carrick MM, Norman MA, Scott BG, Welsh FJ, Tsai P, Liscum KR, Wall MJ Jr and Mattox KL: Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: Preliminary results of a randomized controlled trial. J Trauma. 70:652–663. 2011. View Article : Google Scholar : PubMed/NCBI

14 

White NJ, Wang X, Liles C and Stern S: Fibrinogen concentrate improves survival during limited resuscitation of uncontrolled hemorrhagic shock in a Swine model. Shock. 42:456–463. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Li T, Zhu Y, Hu Y, Li L, Diao Y, Tang J and Liu L: Ideal permissive hypotension to resuscitate uncontrolled hemorrhagic shock and the tolerance time in rats. Anesthesiology. 114:111–119. 2011. View Article : Google Scholar : PubMed/NCBI

16 

Rezende-Neto JB, Rizoli SB, Andrade MV, Lisboa TA and Cunha-Melo JR: Rabbit model of uncontrolled hemorrhagic shock and hypotensive resuscitation. Braz J Med Biol Res. 43:1153–1159. 2010. View Article : Google Scholar : PubMed/NCBI

17 

Lu YQ, Cai XJ, Gu LH, Fan YJ, Wang Q and Bao DG: Effects of three fluid resuscitation methods on apoptosis of visceral organs in rats with hemorrhagic shock. J Zhejiang Univ Sci B. 6:907–912. 2005. View Article : Google Scholar : PubMed/NCBI

18 

Ho L, Lau L, Churilov L, Riedel B, McNicol L, Hahn RG and Weinberg L: Comparative evaluation of crystalloid resuscitation rate in a human model of compensated haemorrhagic shock. Shock. 46:149–157. 2016. View Article : Google Scholar : PubMed/NCBI

19 

De Backer D, Ospina-Tascon G, Salgado D, Favory R, Creteur J and Vincent JL: Monitoring the microcirculation in the critically ill patient: Current methods and future approaches. Intensive Care Med. 36:1813–1825. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Venge P, Eriksson A-K, Douhan-Håkansson L and Pauksen K: Human neutrophil lipocalin in activated whole blood is a specific and rapid diagnostic biomarker of bacterial infections in the respiratory tract. Clin Vaccine Immunol. 24:e00064–e17. 2017. View Article : Google Scholar : PubMed/NCBI

21 

Venge P, Douhan-Håkansson L, Garwicz D, Peterson C, Xu S and Pauksen K: Human neutrophil lipocalin as a superior diagnostic means to distinguish between acute bacterial and viral infections. Clin Vaccine Immunol. 22:1025–1032. 2015. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yu J, Peng J, Hui L, Huang H, Tan M and Jian G: Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin. Exp Ther Med 16: 3534-3538, 2018.
APA
Yu, J., Peng, J., Hui, L., Huang, H., Tan, M., & Jian, G. (2018). Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin. Experimental and Therapeutic Medicine, 16, 3534-3538. https://doi.org/10.3892/etm.2018.6591
MLA
Yu, J., Peng, J., Hui, L., Huang, H., Tan, M., Jian, G."Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin". Experimental and Therapeutic Medicine 16.4 (2018): 3534-3538.
Chicago
Yu, J., Peng, J., Hui, L., Huang, H., Tan, M., Jian, G."Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin". Experimental and Therapeutic Medicine 16, no. 4 (2018): 3534-3538. https://doi.org/10.3892/etm.2018.6591
Copy and paste a formatted citation
x
Spandidos Publications style
Yu J, Peng J, Hui L, Huang H, Tan M and Jian G: Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin. Exp Ther Med 16: 3534-3538, 2018.
APA
Yu, J., Peng, J., Hui, L., Huang, H., Tan, M., & Jian, G. (2018). Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin. Experimental and Therapeutic Medicine, 16, 3534-3538. https://doi.org/10.3892/etm.2018.6591
MLA
Yu, J., Peng, J., Hui, L., Huang, H., Tan, M., Jian, G."Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin". Experimental and Therapeutic Medicine 16.4 (2018): 3534-3538.
Chicago
Yu, J., Peng, J., Hui, L., Huang, H., Tan, M., Jian, G."Association between the effect of controlled fluid resuscitation on massive hemorrhage and expression of human neutrophil lipocalin". Experimental and Therapeutic Medicine 16, no. 4 (2018): 3534-3538. https://doi.org/10.3892/etm.2018.6591
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team