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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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October-2019 Volume 18 Issue 4

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Case Report

Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report

  • Authors:
    • Mingyuan Zhang
    • Kefeng Ding
  • View Affiliations / Copyright

    Affiliations: Colorectal Surgery Department, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China
  • Pages: 2726-2730
    |
    Published online on: August 5, 2019
       https://doi.org/10.3892/etm.2019.7852
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Abstract

Megacolon is a congenital disorder. Adult congenital megacolon (ACM), also known as adult Hirschsprung's disease, is rare and frequently manifests as constipation. ACM is caused by the absence of ganglion cells in the submucosa or myenteric plexus of the bowel. Most patients undergo treatment of megacolon at a young age, but certain patients cannot be treated until they develop bowel obstruction in adulthood. Bowel obstruction in adults always occurs in complex clinical situations and it is frequently combined with comorbidities, including bowel tumors, volvulus, hernias, hypertension or diabetes mellitus. Surgical intervention is always required in such cases. To avoid recurrence, a sufficient amount of bowel should be removed, particularly the aganglionic segment. Furthermore, the patient's general physical condition should be considered pre‑operatively by controlling parameters including blood pressure and blood glucose. In the present study, a case of ACM combined with fecal impaction and diabetic nephropathy was presented.
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1 

Fortea-Sanchís C, Martínez-Ramos D, Rivadulla-Serrano I, Daroca-José JM, Paiva-Coronel G and Salvador-Sanchís JL: Hirschprung's disease in adults. Rev Esp Enferm Dig. 103:150–151. 2011. View Article : Google Scholar : PubMed/NCBI

2 

López Ruiz JA, Tallón Aguilar L, Sánchez Moreno L, López Pérez J, Pareja Ciuró F, Oliva Mompeán F and Padillo Ruiz FJ: Hirschsprung disease with debut in adult age as acute intestinal obstruction: Case report. Rev Esp Enferm Dig. 108:742–746. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Lou Z, Meng RG, Yu ED, Liu LJ, Hao LQ, Wang HT and Fu CG: Diagnosis and surgical treatment of adult Hirschsprung's disease. Zhonghua Wei Chang Wai Ke Za Zhi. 8:304–305. 2005.(In Chinese). PubMed/NCBI

4 

Doodnath R and Puri P: A systematic review and meta-analysis of Hirschsprung's disease presenting after childhood. Pediatr Surg Int. 26:1107–1110. 2010. View Article : Google Scholar : PubMed/NCBI

5 

Wu S, Sun X, Yu Y and Shen Y: Hirschsprung's disease-related sigmoid vulvulus complicated with refractory hypertension. Am J Case Rep. 19:467–471. 2018. View Article : Google Scholar : PubMed/NCBI

6 

Shitta AH, Ugwu BT, Peter SD, Ozoilo KN, Adighije PF and Omolabake BI: Hirschsprung's disease in an adult: A case report. J West Afr Coll Surg. 4:121–126. 2014.PubMed/NCBI

7 

Rosin JD, Bargen JA and Waugh JM: Congenital megacolon of a man 54 years of age: Report of case. Proc Staff Meet Mayo Clin. 25:710–715. 1950.PubMed/NCBI

8 

Qiu JF, Shi YJ, Hu L, Fang L, Wang HF and Zhang MC: Adult Hirschsprung's disease: Report of four cases. Int J Clin Exp Pathol. 6:1624–1630. 2013.PubMed/NCBI

9 

Qi Z and Zhang W: Adult congenital megacolon with bowel obstruction: A case report. Chin J Gastroenterol Hepatolt. 26:1131–1132. 2017.(In Chinese).

10 

Ding SQ, Chen YT, Ding YJ, Fang L, Wang HF and Zhang MC: Diagnosis and surgical management of adult Hirschsprung disease. Zhonghua Wei Chang Wai Ke Za Zhi. 9:53–55. 2006.(In Chinese). PubMed/NCBI

11 

Kim HJ, Kim AY, Lee CW, Yu CS, Kim JS, Kim PN, Lee MG and Ha HK: Hirschsprung disease and hypoganglionosis in adults: Radiologic findings and differentiation. Radiology. 247:428–434. 2008. View Article : Google Scholar : PubMed/NCBI

12 

Li F and Chen Y: Diagnosis and surgical treatment of adult Hirschsprung's disease. Chin J Gen Surg. 9:452–454. 2000.(In Chinese).

13 

Chen X, Xiaojuan W, Zhang H, Jiao C, Yu K, Zhu T and Feng J: Diagnostic value of the preoperatively detected radiological transition zone in Hirschsprung's disease. Pediatr Surg Int. 33:581–586. 2017. View Article : Google Scholar : PubMed/NCBI

14 

Arshad A, Powell C and Tighe MP: Hirschsprung's disease. BMJ. 345:e55212012. View Article : Google Scholar : PubMed/NCBI

15 

Holschneiderd AM, Meier-Ruge W and Ure BM: Hirschsprung's disease and allied disorders-a review. Eur J Pediatr Surg. 4:260–266. 1994. View Article : Google Scholar : PubMed/NCBI

16 

Fu CG, Muto T, Masaki T and Nagawa H: Zonal adult Hirschsprung's disease. Gut. 39:765–767. 1996. View Article : Google Scholar : PubMed/NCBI

17 

Edery P, Lyonnet S, Muligan LM, Pelet A, Dow E, Abel L, Holder S, Nihoul-Fékété C, Ponder BA and Munnich A: Mutations of the RET proto-oncogene in Hirschsprung disease. Nature. 367:378–380. 1994. View Article : Google Scholar : PubMed/NCBI

18 

Romeo G, Ronchetto P, Yin L, Barone V, Seri M, Ceccherini I, Pasini B, Bocciardi R, Lerone M, Kääriäinen H, et al: Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease. Nature. 367:377–378. 1994. View Article : Google Scholar : PubMed/NCBI

19 

Martuccielb G, Ceccherim I, Lerong M and Jasonni V: Pathogenesis of Hirschsprung's disease. J Pediatr Surg. 55:1017–1025. 2000.

20 

He X, Xu D and Li L: Congenital megacolon with Laporoscopic-assisted treatment: 20 cases report. J Laporoscopic surg. 14:55–56. 2009.

21 

Wang G: The treatment progession and micro invasive surgery of Congenital megacolon. Chin J Pediatr surg. 23:103–104. 2003.(In Chinese).

22 

Jarry J and Faucheron JL: Laparoscopic rectosigmoid resection with transanal colonic pull-through and delayed coloanal anastomosis: A new approach to adult Hirschsprung disease. Dis Colon Rectum. 54:1313–1319. 2011. View Article : Google Scholar : PubMed/NCBI

23 

Miniello S, Marzaioli R, Balzanelli MG, Dantona C, Lippolis AS, Barnabà D and Nacchiero M: Toxic megacolon in ulcerative rectocolitis. Current trends in clinical evaluation, diagnosis and treatment. Ann Ital Chir. 85:45–49. 2014.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang M and Ding K: Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report. Exp Ther Med 18: 2726-2730, 2019.
APA
Zhang, M., & Ding, K. (2019). Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report. Experimental and Therapeutic Medicine, 18, 2726-2730. https://doi.org/10.3892/etm.2019.7852
MLA
Zhang, M., Ding, K."Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report". Experimental and Therapeutic Medicine 18.4 (2019): 2726-2730.
Chicago
Zhang, M., Ding, K."Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report". Experimental and Therapeutic Medicine 18, no. 4 (2019): 2726-2730. https://doi.org/10.3892/etm.2019.7852
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang M and Ding K: Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report. Exp Ther Med 18: 2726-2730, 2019.
APA
Zhang, M., & Ding, K. (2019). Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report. Experimental and Therapeutic Medicine, 18, 2726-2730. https://doi.org/10.3892/etm.2019.7852
MLA
Zhang, M., Ding, K."Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report". Experimental and Therapeutic Medicine 18.4 (2019): 2726-2730.
Chicago
Zhang, M., Ding, K."Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report". Experimental and Therapeutic Medicine 18, no. 4 (2019): 2726-2730. https://doi.org/10.3892/etm.2019.7852
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