Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report

Zhang,Mingyuan; Ding,Kefeng

doi:10.3892/etm.2019.7852

Adult congenital megacolon with acute fecal obstruction and diabetic nephropathy: A case report

Authors:
- Mingyuan Zhang
- Kefeng Ding
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Affiliations: Colorectal Surgery Department, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China
Published online on: August 5, 2019 https://doi.org/10.3892/etm.2019.7852
Pages: 2726-2730

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Abstract

Megacolon is a congenital disorder. Adult congenital megacolon (ACM), also known as adult Hirschsprung's disease, is rare and frequently manifests as constipation. ACM is caused by the absence of ganglion cells in the submucosa or myenteric plexus of the bowel. Most patients undergo treatment of megacolon at a young age, but certain patients cannot be treated until they develop bowel obstruction in adulthood. Bowel obstruction in adults always occurs in complex clinical situations and it is frequently combined with comorbidities, including bowel tumors, volvulus, hernias, hypertension or diabetes mellitus. Surgical intervention is always required in such cases. To avoid recurrence, a sufficient amount of bowel should be removed, particularly the aganglionic segment. Furthermore, the patient's general physical condition should be considered pre‑operatively by controlling parameters including blood pressure and blood glucose. In the present study, a case of ACM combined with fecal impaction and diabetic nephropathy was presented.

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