Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
October-2019 Volume 18 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2019 Volume 18 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury

  • Authors:
    • Fanpeng Meng
    • Haiyuan Wu
    • Shuguang Yang
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Shanxian Central Hospital, Heze, Shandong 274300, P.R. China, Department of Pathology, Shanxian Central Hospital, Heze, Shandong 274300, P.R. China
    Copyright: © Meng et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2497-2502
    |
    Published online on: August 7, 2019
       https://doi.org/10.3892/etm.2019.7860
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

This study explored the clinical application of ventriculoperitoneal (VP) shunting in treating traumatic brain injury (TBI). A retrospective analysis was performed on 100 patients who had hydrocephalus due to TBI and were admitted to Shanxian Central Hospital from February 2012 to June 2016. Among these patients, 50 underwent VP shunting surgery and were assigned to the experimental group. The remaining 50 underwent lumboperitoneal (LP) shunting surgery and were assigned to the control group. Twenty days after surgery, all patients were evaluated for clinical outcomes, neurological deficit scores and complications. The results were compared between the two groups. Patients in the experimental group were further separated into three subgroups according to the severity of hydrocephalus, and clinical outcomes were compared among the subgroups. It was found that the effective rate in the experimental group was significantly higher than that in the control group, and the difference was statistically significant (P<0.05). The effective rate in the mild hydrocephalus subgroup was significantly higher than that in the severe hydrocephalus subgroup, with a statistically significant difference (P<0.05). The effective rate in the moderate hydrocephalus subgroup was significantly higher than that in the severe hydrocephalus subgroup, with a statistically significant difference (P<0.05). The incidence of complications in the control group was significantly higher than that in the experimental group, and the difference was statistically significant (P<0.05). The postoperative neurological deficit score in the experimental group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). In conclusion, patients with hydrocephalus due to TBI had better clinical outcome when treated with VP shunting than those treated with LP shunting. Moreover, a better outcome was observed when the patient had milder hydrocephalus. Therefore, the early diagnosis and timely treatment with VP shunting are of great importance for patients with hydrocephalus.
View Figures

Figure 1

View References

1 

Hyder AA, Wunderlich CA, Puvanachandra P, Gururaj G and Kobusingye OC: The impact of traumatic brain injuries: A global perspective. NeuroRehabilitation. 22:341–353. 2007.PubMed/NCBI

2 

Ommaya AK and Gennarelli TA: Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries. Brain. 97:633–654. 1974. View Article : Google Scholar : PubMed/NCBI

3 

McCrea M, Iverson GL, McAllister TW, Hammeke TA, Powell MR, Barr WB and Kelly JP: An integrated review of recovery after mild traumatic brain injury (MTBI): Implications for clinical management. Clin Neuropsychol. 23:1368–1390. 2009. View Article : Google Scholar : PubMed/NCBI

4 

Graham DI, Adams JH and Doyle D: Ischaemic brain damage in fatal non-missile head injuries. J Neurol Sci. 39:213–234. 1978. View Article : Google Scholar : PubMed/NCBI

5 

Bryant RA, O'Donnell ML, Creamer M, McFarlane AC, Clark CR and Silove D: The psychiatric sequelae of traumatic injury. Am J Psychiatry. 167:312–320. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Taylor CA, Bell JM, Breiding MJ and Xu L: Traumatic brain injury-related emergency department visits, hospitalizations, and deaths - United States, 2007 and 2013. MMWR Surveill Summ. 66:1–16. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Ommaya AK, Goldsmith W and Thibault L: Biomechanics and neuropathology of adult and paediatric head injury. Br J Neurosurg. 16:220–242. 2002. View Article : Google Scholar : PubMed/NCBI

8 

Zhang J, Williams MA and Rigamonti D: Genetics of human hydrocephalus. J Neurol. 253:1255–1266. 2006. View Article : Google Scholar : PubMed/NCBI

9 

Bering EA Jr and Sato O: Hydrocephalus: Changes in formation and absorption of cerebrospinal fluid within the cerebral ventricles. J Neurosurg. 20:1050–1063. 1963. View Article : Google Scholar : PubMed/NCBI

10 

Dixon GR, Friedman JA, Luetmer PH, Quast LM, McClelland RL, Petersen RC, Maher CO and Ebersold MJ: Use of cerebrospinal fluid flow rates measured by phase-contrast MR to predict outcome of ventriculoperitoneal shunting for idiopathic normal-pressure hydrocephalus. Mayo Clin Proc. 77:509–514. 2002. View Article : Google Scholar : PubMed/NCBI

11 

Battal B, Kocaoglu M, Bulakbasi N, Husmen G, Tuba Sanal H and Tayfun C: Cerebrospinal fluid flow imaging by using phase-contrast MR technique. Br J Radiol. 84:758–765. 2011. View Article : Google Scholar : PubMed/NCBI

12 

Schoenbaum SC, Gardner P and Shillito J: Infections of cerebrospinal fluid shunts: Epidemiology, clinical manifestations, and therapy. J Infect Dis. 131:543–552. 1975. View Article : Google Scholar : PubMed/NCBI

13 

Reddy GK, Bollam P, Caldito G, Willis B, Guthikonda B and Nanda A: Ventriculoperitoneal shunt complications in hydrocephalus patients with intracranial tumors: An analysis of relevant risk factors. J Neurooncol. 103:333–342. 2011. View Article : Google Scholar : PubMed/NCBI

14 

Zhang J, Qu C, Wang Z, Wang C, Ding X, Pan S and Ji Y: Improved ventriculoatrial shunt for cerebrospinal fluid diversion after multiple ventriculoperitoneal shunt failures. Surg Neurol. 72 (Suppl 1):S29–S34. 2009. View Article : Google Scholar : PubMed/NCBI

15 

Grosfeld JL, Cooney DR, Smith J and Campbell RL: Intra-abdominal complications following ventriculoperitoneal shunt procedures. Pediatrics. 54:791–796. 1974.PubMed/NCBI

16 

Murtagh F and Lehman R: Peritoneal shunts in the management of hydrocephalus. JAMA. 202:1010–1014. 1967. View Article : Google Scholar : PubMed/NCBI

17 

Limbrick DD Jr, Baird LC, Klimo P Jr, Riva-Cambrin J and Flannery AM; Pediatric Hydrocephalus Systematic Review and Evidence-Based Guidelines Task Force, : Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 4: Cerebrospinal fluid shunt or endoscopic third ventriculostomy for the treatment of hydrocephalus in children. J Neurosurg Pediatr. 14 (Suppl 1):30–34. 2014. View Article : Google Scholar : PubMed/NCBI

18 

Hebb AO and Cusimano MD: Idiopathic normal pressure hydrocephalus: A systematic review of diagnosis and outcome. Neurosurgery. 49:1166–1186. 2001. View Article : Google Scholar : PubMed/NCBI

19 

Constine LS, Konski A, Ekholm S, McDonald S and Rubin P: Adverse effects of brain irradiation correlated with MR and CT imaging. Int J Radiat Oncol Biol Phys. 15:319–330. 1988. View Article : Google Scholar : PubMed/NCBI

20 

Cao M and Wu JI: Camk2a-Cre-mediated conditional deletion of chromatin remodeler Brg1 causes perinatal hydrocephalus. Neurosci Lett. 597:71–76. 2015. View Article : Google Scholar : PubMed/NCBI

21 

Walker WC and McDonald SD: Does neurologic examination during inpatient rehabilitation help predict global outcome after nonpenetrating traumatic brain injury? PM R. 3:6–12. 2011. View Article : Google Scholar : PubMed/NCBI

22 

McDonald S and Flanagan S: Social perception deficits after traumatic brain injury: Interaction between emotion recognition, mentalizing ability, and social communication. Neuropsychology. 18:572–579. 2004. View Article : Google Scholar : PubMed/NCBI

23 

Yang XF, Wen L, Shen F, Li G, Lou R, Liu WG and Zhan RY: Surgical complications secondary to decompressive craniectomy in patients with a head injury: A series of 108 consecutive cases. Acta Neurochir (Wien). 150:1241–1248. 2008. View Article : Google Scholar : PubMed/NCBI

24 

Rekate HL: A contemporary definition and classification of hydrocephalus. Semin Pediatr Neurol. 16:9–15. 2009. View Article : Google Scholar : PubMed/NCBI

25 

Chumas PD, Armstrong DC, Drake JM, Kulkarni AV, Hoffman HJ, Humphreys RP, Rutka JT and Hendrick EB: Tonsillar herniation: The rule rather than the exception after lumboperitoneal shunting in the pediatric population. J Neurosurg. 78:568–573. 1993. View Article : Google Scholar : PubMed/NCBI

26 

Chung JJ, Yu JS, Kim JH, Nam SJ and Kim MJ: Intraabdominal complications secondary to ventriculoperitoneal shunts: CT findings and review of the literature. AJR Am J Roentgenol. 193:1311–1317. 2009. View Article : Google Scholar : PubMed/NCBI

27 

Pudenz RH and Foltz EL: Hydrocephalus: Overdrainage by ventricular shunts. A review and recommendations. Surg Neurol. 35:200–212. 1991. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Meng F, Wu H and Yang S: Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury. Exp Ther Med 18: 2497-2502, 2019.
APA
Meng, F., Wu, H., & Yang, S. (2019). Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury. Experimental and Therapeutic Medicine, 18, 2497-2502. https://doi.org/10.3892/etm.2019.7860
MLA
Meng, F., Wu, H., Yang, S."Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury". Experimental and Therapeutic Medicine 18.4 (2019): 2497-2502.
Chicago
Meng, F., Wu, H., Yang, S."Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury". Experimental and Therapeutic Medicine 18, no. 4 (2019): 2497-2502. https://doi.org/10.3892/etm.2019.7860
Copy and paste a formatted citation
x
Spandidos Publications style
Meng F, Wu H and Yang S: Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury. Exp Ther Med 18: 2497-2502, 2019.
APA
Meng, F., Wu, H., & Yang, S. (2019). Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury. Experimental and Therapeutic Medicine, 18, 2497-2502. https://doi.org/10.3892/etm.2019.7860
MLA
Meng, F., Wu, H., Yang, S."Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury". Experimental and Therapeutic Medicine 18.4 (2019): 2497-2502.
Chicago
Meng, F., Wu, H., Yang, S."Clinical application of ventriculoperitoneal shunting in treating traumatic brain injury". Experimental and Therapeutic Medicine 18, no. 4 (2019): 2497-2502. https://doi.org/10.3892/etm.2019.7860
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team