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Review Open Access

Recent progress regarding kaempferol for the treatment of various diseases (Review)

  • Authors:
    • Jie Ren
    • Yifei Lu
    • Yanhong Qian
    • Bozhou Chen
    • Tao Wu
    • Guang Ji
  • View Affiliations / Copyright

    Affiliations: Center of Chinese Medical Therapy and Systems Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China, Institute of Digestive Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, P.R. China
    Copyright: © Ren et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2759-2776
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    Published online on: August 13, 2019
       https://doi.org/10.3892/etm.2019.7886
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Abstract

Kaempferol, also known as kaempferol‑3 or kaempferide, is a flavonoid compound that naturally occurs in tea, as well as numerous common vegetables and fruits, including beans, broccoli, cabbage, gooseberries, grapes, kale, strawberries, tomatoes, citrus fruits, brussel sprouts, apples and grapefruit. The present review mainly summarizes the application of kaempferol in treating diseases and the underlying mechanisms that are currently being studied. Due to its anti‑inflammatory properties, it may be used to treat numerous acute and chronic inflammation‑induced diseases, including intervertebral disc degeneration and colitis, as well as post‑menopausal bone loss and acute lung injury. In addition, it has beneficial effects against cancer, liver injury, obesity and diabetes, inhibits vascular endothelial inflammation, protects the cranial nerve and heart function, and may be used for treating fibroproliferative disorders, including hypertrophic scar
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Copy and paste a formatted citation
Spandidos Publications style
Ren J, Lu Y, Qian Y, Chen B, Wu T and Ji G: Recent progress regarding kaempferol for the treatment of various diseases (Review). Exp Ther Med 18: 2759-2776, 2019.
APA
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., & Ji, G. (2019). Recent progress regarding kaempferol for the treatment of various diseases (Review). Experimental and Therapeutic Medicine, 18, 2759-2776. https://doi.org/10.3892/etm.2019.7886
MLA
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., Ji, G."Recent progress regarding kaempferol for the treatment of various diseases (Review)". Experimental and Therapeutic Medicine 18.4 (2019): 2759-2776.
Chicago
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., Ji, G."Recent progress regarding kaempferol for the treatment of various diseases (Review)". Experimental and Therapeutic Medicine 18, no. 4 (2019): 2759-2776. https://doi.org/10.3892/etm.2019.7886
Copy and paste a formatted citation
x
Spandidos Publications style
Ren J, Lu Y, Qian Y, Chen B, Wu T and Ji G: Recent progress regarding kaempferol for the treatment of various diseases (Review). Exp Ther Med 18: 2759-2776, 2019.
APA
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., & Ji, G. (2019). Recent progress regarding kaempferol for the treatment of various diseases (Review). Experimental and Therapeutic Medicine, 18, 2759-2776. https://doi.org/10.3892/etm.2019.7886
MLA
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., Ji, G."Recent progress regarding kaempferol for the treatment of various diseases (Review)". Experimental and Therapeutic Medicine 18.4 (2019): 2759-2776.
Chicago
Ren, J., Lu, Y., Qian, Y., Chen, B., Wu, T., Ji, G."Recent progress regarding kaempferol for the treatment of various diseases (Review)". Experimental and Therapeutic Medicine 18, no. 4 (2019): 2759-2776. https://doi.org/10.3892/etm.2019.7886
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