Cystic adventitial disease of femoral vein presenting as enlarging lower limb swelling and pain: Two case reports and review of the literature

Liu,Peng; Yan,Bin; Zhang,Yanhui; Yan,Jingwei; Ma,Chong; Wang,Guodong; Jian,Tao; Sun,Ziqiang

doi:10.3892/etm.2019.7992

Cystic adventitial disease of femoral vein presenting as enlarging lower limb swelling and pain: Two case reports and review of the literature

Authors:
- Peng Liu
- Bin Yan
- Yanhui Zhang
- Jingwei Yan
- Chong Ma
- Guodong Wang
- Tao Jian
- Ziqiang Sun
View Affiliations

Affiliations: Department of Vascular Surgery, Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China, Intensive Care Unit of Vascular Surgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, P.R. China, Department of Oncology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China
Published online on: September 9, 2019 https://doi.org/10.3892/etm.2019.7992
Pages: 3563-3567
Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )

Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )

Cited By (CrossRef): 0 citations Loading Articles...

Abstract

Cystic adventitial disease (CAD) is a condition that mainly affects the arterial system but rarely involves the venous system. The present study reported on two cases of CAD of femoral veins. The clinical manifestations in the two patients included pain and swelling of the lower limbs, but they had no risk factors for venous thrombosis. Color ultrasonography indicated cystic space‑occupying lesions around the femoral veins, and enhanced computed tomography (CT) revealed vascular compression and space‑occupying properties of the femoral veins. The two patients underwent open surgery, the postoperative treatment was uneventful, and swelling and tenderness were completely resolved. The pathological examination confirmed CAD of femoral vein in the two patients. The enhanced CT venography scan indicated patency of the femoral vein in the two patients following the operation. The circumferences of the two patients' lower limbs had returned to normal at the 2‑month follow‑up. A review of the literature was performed, and the presentation, diagnosis, treatment and pathology of this rare condition were discussed.

View Figures

View References

1	Lezotte J, Le QP, Shanley C and Hans S: Adventitial cystic disease: Complicated and uncomplicated. Ann Vasc Surg. 46:370.e13–370.e15. 2018. View Article : Google Scholar
2	Li S, King BN, Velasco N, Kumar Y and Gupta N: Cystic adventitial disease-case series and review of literature. Ann Transl Med. 5:3272017. View Article : Google Scholar : PubMed/NCBI
3	Scott MF, Gavin T and Levin S: Venous cystic adventitial disease presenting as an enlarging groin mass. Ann Vasc Surg. 28:489.e15–8. 2014. View Article : Google Scholar
4	Levien LJ and Benn CA: Adventitial cystic disease: A unifying hypothesis. J Vasc Surg. 28:193–205. 1998. View Article : Google Scholar : PubMed/NCBI
5	Chen Y, Sun R, Shao J, Li Y and Liu C: A contemporary review of venous adventitial cystic disease and three case reports. Phlebology. 30:11–16. 2015. View Article : Google Scholar : PubMed/NCBI
6	Kim YK, Chun HJ, Hwang JK, Kim JI, Kim SD, Park SC and Moon IS: Adventitial cystic disease of the common femoral vein presenting as deep vein thrombosis. Asian J Surg. 39:178–181. 2016. View Article : Google Scholar : PubMed/NCBI
7	Manning MW, Dunkman WJ and Miller TE: Perioperative fluid and hemodynamic management within an enhanced recovery pathway. J Surg Oncol. 116:592–600. 2017. View Article : Google Scholar : PubMed/NCBI
8	Atkins HJ and Key JA: A case of myxomatous tumour arising in the adventitia of the left external iliac artery; case report. Br J Surg. 34:4261947. View Article : Google Scholar : PubMed/NCBI
9	Mentha C: Mucoid degeneration of veins. J Cardiovasc Surg (Torino). 4:591–594. 1963.(In French). PubMed/NCBI
10	Desy NM and Spinner RJ: The etiology and management of cystic adventitial disease. J Vasc Surg. 60:235–245. 2014. View Article : Google Scholar : PubMed/NCBI
11	Dix FP, McDonald M, Obomighie J, Chalmers N, Thompson D, Benbow EW and Smyth JV: Cystic adventitial disease of the femoral vein presenting as deep vein thrombosis: A case report and review of the literature. J Vasc Surg. 44:871–874. 2006. View Article : Google Scholar : PubMed/NCBI
12	Spinner RJ, Desy NM, Agarwal G, Pawlina W, Kalra M and Amrami KK: Evidence to support that adventitial cysts, analogous to intraneural ganglion cysts, are also joint-connected. Clin Anat. 26:267–281. 2013. View Article : Google Scholar : PubMed/NCBI
13	Kim HK, Hwang D, Park S, Jeong WJ, Seo AN and Huh S: Cystic disease of the groin presenting as compression of a femoral vessel. Vasc Specialist Int. 32:124–128. 2016. View Article : Google Scholar : PubMed/NCBI
14	Mousa AY, Alhalbouni S, Abu-Halimah S, Gill G, Sadek B, Nanjundappa A, Hass SM and Aburahma AF: Cystic adventitial disease of the common femoral vein: A case report and review of the literature. Vasc Endovascular Surg. 47:569–572. 2013. View Article : Google Scholar : PubMed/NCBI
15	Wu X, Lun Y, Jiang H, Gang Q, Duan Z, Xin S and Zhang J: Cystic adventitial disease of the common femoral vessels: Report of 2 cases and literature review. Vasc Endovascular Surg. 48:325–328. 2014. View Article : Google Scholar : PubMed/NCBI
16	Seo JY, Chung DJ and Kim JH: Adventitial cystic disease of the femoral vein: A case report with the CT venography. Korean J Radiol. 10:89–92. 2009. View Article : Google Scholar : PubMed/NCBI
17	Bascone C, Iqbal M, Narh-Martey P, Szuchmacher M, Cicchillo M and Krishnasastry KV: Venous adventitial cystic disease: A review of 45 cases treated since 1963. Int J Vasc Med. 2016:52876972016.PubMed/NCBI
18	Takizawa K, Osawa H, Kojima A, Abraham SJK and Hosaka S: Cystic adventitial disease of popliteal artery with venous aneurysm of popliteal vein: Two-year follow-up after surgery. Case Rep Vasc Med. 2017:48734742017.PubMed/NCBI
19	Johnson JM, Kiankhooy A, Bertges DJ and Morris CS: Percutaneous image-guided aspiration and sclerosis of adventitial cystic disease of the femoral vein. Cardiovasc Intervent Radiol. 32:812–816. 2009. View Article : Google Scholar : PubMed/NCBI
20	Roth JA, Kearney P and Wittmann CJ: Cystic adventitial degeneration of the common femoral artery. Arch Surg. 112:210–212. 1977. View Article : Google Scholar : PubMed/NCBI