Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
November-2019 Volume 18 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-2019 Volume 18 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Article

The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions

  • Authors:
    • Bowen Shi
    • Fei Shi
    • Ke Xu
    • Liuhui Shi
    • Haixiao Tang
    • Ning Wang
    • Yanyuan Wu
    • Jun Gu
    • Jie Ding
    • Yunteng Huang
  • View Affiliations / Copyright

    Affiliations: Department of Urology, School of Medicine, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200092, P.R. China, Department of Urology, Civil Aviation Hospital, Shanghai 200000, P.R. China, Department of Urology, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu, Jiangsu 215500, P.R. China
  • Pages: 4165-4172
    |
    Published online on: September 26, 2019
       https://doi.org/10.3892/etm.2019.8057
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the present study was to validate the prognostic effectiveness of Sepsis‑3 criteria, including sequential organ failure assessment (SOFA) and quick SOFA (qSOFA), with systemic inflammatory response syndrome (SIRS) criteria among patients with urolithiasis associated sepsis that were transferred to intensive care unit (ICU) facilities following surgical interventions. To achieve this, the records of all patients transferred to ICU following surgical interventions with urolithiasis‑associated sepsis between January 2010 to July 2017 at Xin Hua Hospital Affiliated to Shanghai Jiao Tong University were retrospectively reviewed. A total of 107 patients were enrolled. The prognostic performances of SOFA, qSOFA and SIRS for predicting in‑hospital mortality (sepsis‑related mortality during patients' hospitalizations) or prolonged length of ICU stay (>3 days) were compared using the area under the receiver operating characteristic curve (AUROC) and Z statistic values. The results revealed that the overall in‑hospital mortality rate was 8.4% and the percentage of in‑hospital mortality or prolonged length of ICU stay (>3 days) was 72.0% among the 107 patients. The favorable outcome group exhibited significantly decreased white blood cell counts, and levels of C‑reactive protein and procalcitonin and increased systolic blood pressure and mean arterial pressure. The AUROC of qSOFA, SIRS and SOFA were 0.615, 0.625 and 0.860, respectively. SOFA was significantly more effective at predicting adverse outcomes when compared with SIRS and qSOFA criteria. Following adjustments for patient age and comorbidities, the AUROC values of qSOFA, SIRS and SOFA were 0.713, 0.722 and 0.940. In conclusion, the results of the present study indicate that the prognostic performance of SOFA for predicting in‑hospital mortality or prolonged ICU stay among patients with urolithiasis‑associated sepsis following surgical interventions was significantly improved when compared with qSOFA or SIRS criteria. Based on these results it is recommended that urologists use the SOFA score for patients with urolithiasis‑associated sepsis.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Gotts JE and Matthay MA: Sepsis: Pathophysiology and clinical management. BMJ. 353:i15852016. View Article : Google Scholar : PubMed/NCBI

2 

Cohen J, Vincent JL, Adhikari NK, Machado FR, Angus DC, Calandra T, Jaton K, Giulieri S, Delaloye J, Opal S, et al: Sepsis: A roadmap for future research. Lancet Infect Dis. 15:581–614. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al: The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 315:801–810. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Shankar-Hari M, Phillips GS, Levy ML, Seymour CW, Liu VX, Deutschman CS, Angus DC, Rubenfeld GD and Singer M; Sepsis Definitions Task Force, : Developing a new definition and assessing new clinical criteria for septic shock: For the third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 315:775–787. 2016. View Article : Google Scholar : PubMed/NCBI

5 

Seymour CW, Liu VX, Iwashyna TJ, Brunkhorst FM, Rea TD, Scherag A, Rubenfeld G, Kahn JM, Shankar-Hari M, Singer M, et al: Assessment of clinical criteria for sepsis: For the third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 315:762–774. 2016. View Article : Google Scholar : PubMed/NCBI

6 

Dreger NM, Degener S, Ahmad-Nejad P, Wöbker G and Roth S: Urosepsis-etiology, diagnosis and treatment. Dtsch Arztebl Int. 112:837–848. 2015.PubMed/NCBI

7 

Wagenlehner FM, Pilatz A, Weidner W and Naber KG: Urosepsis: Overview of the diagnostic and treatment challenges. Microbiol Spectr. 32015.doi: 10.1128/microbiolspec.UTI-0003-2012.

8 

Wagenlehner FM, Lichtenstern C, Rolfes C, Mayer K, Uhle F, Weidner W and Weigand MA: Diagnosis and management for urosepsis. Int J Urol. 20:963–970. 2013.PubMed/NCBI

9 

Michel MS, Trojan L and Rassweiler JJ: Complications in percutaneous nephrolithotomy. Eur Urol. 51:899–906. 2007. View Article : Google Scholar : PubMed/NCBI

10 

Koras O, Bozkurt IH, Yonguc T, Degirmenci T, Arslan B, Gunlusoy B, Aydogdu O and Minareci S: Risk factors for postoperative infectious complications following percutaneous nephrolithotomy: A prospective clinical study. Urolithiasis. 43:55–60. 2015. View Article : Google Scholar : PubMed/NCBI

11 

Çıtamak B, Altan M, Bozacı AC, Koni A, Doğan HS, Bilen CY, Şahin A and Tekgül S: Percutaneous nephrolithotomy in children: 17 Years of experience. J Urol. 195:1082–1087. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Wu H, Zhu S, Yu S, Ding G, Xu J, Li T, Qiao L, Chen Y, Yan J, Cheng X, et al: Early drastic decrease in white blood count can predict uroseptic shock induced by upper urinary tract endoscopic lithotripsy: A translational study. J Urol. 193:2116–2122. 2015. View Article : Google Scholar : PubMed/NCBI

13 

Hu M, Zhong X, Cui X, Xu X, Zhang Z, Guan L, Feng Q, Huang Y and Hu W: Development and validation of a risk-prediction nomogram for patients with ureteral calculi associated with urosepsis: A retrospective analysis. PLoS One. 13:e02015152018. View Article : Google Scholar : PubMed/NCBI

14 

Freund Y, Lemachatti N, Krastinova E, Van Laer M, Claessens YE, Avondo A, Occelli C, Feral-Pierssens AL, Truchot J, Ortega M, et al: Prognostic accuracy of sepsis-3 criteria for in-hospital mortality among patients with suspected infection presenting to the emergency department. JAMA. 317:301–308. 2017. View Article : Google Scholar : PubMed/NCBI

15 

Raith EP, Udy AA, Bailey M, McGloughlin S, MacIsaac C, Bellomo R and Pilcher DV: Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE): Prognostic accuracy of the SOFA score, SIRS criteria and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit. JAMA. 317:290–300. 2017. View Article : Google Scholar : PubMed/NCBI

16 

Tokioka F, Okamoto H, Yamazaki A, Itou A and Ishida T: The prognostic performance of qSOFA for community-acquired pneumonia. J Intensive Care. 6:462018. View Article : Google Scholar : PubMed/NCBI

17 

Singer AJ, Ng J, Thode HC Jr, Spiegel R and Weingart S: Quick SOFA scores predict mortality in adult emergency department patients with and without suspected infection. Ann Emerg Med. 69:475–479. 2017. View Article : Google Scholar : PubMed/NCBI

18 

Park HK, Kim WY, Kim MC, Jung W and Ko BS: Quick sequential organ failure assessment compared to systemic inflammatory response syndrome for predicting sepsis in emergency department. J Crit Care. 42:12–17. 2017. View Article : Google Scholar : PubMed/NCBI

19 

Williams JM, Greenslade JH, McKenzie JV, Chu K, Brown AFT and Lipman J: Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: Insights from a prospective database of ED patients with infection. Chest. 151:586–596. 2017. View Article : Google Scholar : PubMed/NCBI

20 

Luo X, Yang X, Li J, Zou G, Lin Y, Qing G, Yang R, Yao W and Ye X: The procalcitonin/albumin ratio as an early diagnostic predictor in discriminating urosepsis from patients with febrile urinary tract infection. Medicine (Baltimore). 97:e110782018. View Article : Google Scholar : PubMed/NCBI

21 

Wu H, Wang Z, Zhu S, Rao D, Hu L, Qiao L, Chen Y, Yan J, Chen X, Wan SP, et al: Uroseptic shock can be reversed by early intervention based on leukocyte count 2 h post-operation: Animal model and multicenter clinical cohort study. Inflammation. 41:1835–1841. 2018. View Article : Google Scholar : PubMed/NCBI

22 

Wagenlehner FM, Tandogdu Z and Bjerklund Johansen TE: An update on classification and management of urosepsis. Curr Opin Urol. 27:133–137. 2017. View Article : Google Scholar : PubMed/NCBI

23 

Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub M and Knoll T: EAU guidelines on interventional treatment for urolithiasis. Eur Urol. 69:475–482. 2016. View Article : Google Scholar : PubMed/NCBI

24 

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, et al: Surviving sepsis campaign: International guidelines for management of sepsis and septic shock: 2016. Crit Care Med. 45:486–552. 2017. View Article : Google Scholar : PubMed/NCBI

25 

Shapiro N, Howell MD, Bates DW, Angus DC, Ngo L and Talmor D: The association of sepsis syndrome and organ dysfunction with mortality in emergency department patients with suspected infection. Ann Emerg Med. 48:583–590.e1. 2006. View Article : Google Scholar : PubMed/NCBI

26 

Lindvig KP, Nielsen SL, Henriksen DP, Jensen TG, Kolmos HJ, Pedersen C, Vinholt PJ and Lassen AT: Mortality and prognostic factors of patients who have blood cultures performed in the emergency department: A cohort study. Eur J Emerg Med. 23:166–172. 2016. View Article : Google Scholar : PubMed/NCBI

27 

Finkelsztein EJ, Jones DS, Ma KC, Pabón MA, Delgado T, Nakahira K, Arbo JE, Berlin DA, Schenck EJ, Choi AM and Siempos II: Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit. Crit Care. 21:732017. View Article : Google Scholar : PubMed/NCBI

28 

Ho KM and Lan NS: Combining quick sequential organ failure assessment with plasma lactate concentration is comparable to standard sequential organ failure assessment score in predicting mortality of patients with and without suspected infection. J Crit Care. 38:1–5. 2017. View Article : Google Scholar : PubMed/NCBI

29 

Borofsky MS, Walter D, Shah O, Goldfarb DS, Mues AC and Makarov DV: Surgical decompression is associated with decreased mortality in patients with sepsis and ureteral calculi. J Urol. 189:946–951. 2013. View Article : Google Scholar : PubMed/NCBI

30 

de la Rosette J, Denstedt J, Geavlete P, Keeley F, Matsuda T, Pearle M, Preminger G and Traxer O; CROES URS Study Group, : The clinical research office of the endourological society ureteroscopy global study: Indications, complications, and outcomes in 11,885 patients. J Endourol. 28:131–139. 2014. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Shi B, Shi F, Xu K, Shi L, Tang H, Wang N, Wu Y, Gu J, Ding J, Huang Y, Huang Y, et al: The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions. Exp Ther Med 18: 4165-4172, 2019.
APA
Shi, B., Shi, F., Xu, K., Shi, L., Tang, H., Wang, N. ... Huang, Y. (2019). The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions. Experimental and Therapeutic Medicine, 18, 4165-4172. https://doi.org/10.3892/etm.2019.8057
MLA
Shi, B., Shi, F., Xu, K., Shi, L., Tang, H., Wang, N., Wu, Y., Gu, J., Ding, J., Huang, Y."The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions". Experimental and Therapeutic Medicine 18.5 (2019): 4165-4172.
Chicago
Shi, B., Shi, F., Xu, K., Shi, L., Tang, H., Wang, N., Wu, Y., Gu, J., Ding, J., Huang, Y."The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions". Experimental and Therapeutic Medicine 18, no. 5 (2019): 4165-4172. https://doi.org/10.3892/etm.2019.8057
Copy and paste a formatted citation
x
Spandidos Publications style
Shi B, Shi F, Xu K, Shi L, Tang H, Wang N, Wu Y, Gu J, Ding J, Huang Y, Huang Y, et al: The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions. Exp Ther Med 18: 4165-4172, 2019.
APA
Shi, B., Shi, F., Xu, K., Shi, L., Tang, H., Wang, N. ... Huang, Y. (2019). The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions. Experimental and Therapeutic Medicine, 18, 4165-4172. https://doi.org/10.3892/etm.2019.8057
MLA
Shi, B., Shi, F., Xu, K., Shi, L., Tang, H., Wang, N., Wu, Y., Gu, J., Ding, J., Huang, Y."The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions". Experimental and Therapeutic Medicine 18.5 (2019): 4165-4172.
Chicago
Shi, B., Shi, F., Xu, K., Shi, L., Tang, H., Wang, N., Wu, Y., Gu, J., Ding, J., Huang, Y."The prognostic performance of Sepsis‑3 and SIRS criteria for patients with urolithiasis‑associated sepsis transferred to ICU following surgical interventions". Experimental and Therapeutic Medicine 18, no. 5 (2019): 4165-4172. https://doi.org/10.3892/etm.2019.8057
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team