|
1
|
Bijlsma JW, Berenbaum F and Lafeber FP:
Osteoarthritis: An update with relevance for clinical practice.
Lancet. 377:2115–2126. 2011.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Madry H and Cucchiarini M: Advances and
challenges in gene-based approaches for osteoarthritis. J Gene Med.
15:343–355. 2013.PubMed/NCBI View
Article : Google Scholar
|
|
3
|
Scanzello CR and Goldring SR: The role of
synovitis in osteoarthritis pathogenesis. Bone. 51:249–257.
2012.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Litwic AE, Parsons C, Edwards MH,
Jagannath D, Cooper C and Dennison EM: Comment on: Inflammatory
mediators in osteoarthritis: A critical review of the state-of-the
art, prospects, and future challenges. Bone. 106:28–29.
2018.PubMed/NCBI View Article : Google Scholar
|
|
5
|
McCulloch K, Litherland GJ and Rai TS:
Cellular senescence in osteoarthritis pathology. Aging Cell.
16:210–218. 2017.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Hafez HM, Ibrahim MA, Ibrahim SA, Amin EF,
Goma W and Abdelrahman AM: Potential protective effect of
etanercept and aminoguanidine in methotrexate-induced
hepatotoxicity and nephrotoxicity in rats. Eur J Pharmacol.
768:1–12. 2015.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Balaganur V, Pathak NN, Lingaraju MC, More
AS, Latief N, Kumari RR, Kumar D and Tandan SK: Effect of
S-methylisothiourea, an inducible nitric oxide synthase inhibitor,
in joint pain and pathology in surgically induced model of
osteoarthritis. Connect Tissue Res. 55:367–377. 2014.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Shirazi I, Yaron I, Wollman Y, Blum M,
Chernihovsky T, Judovich R, Iaina A and Yaron M: Down regulation of
interleukin 1beta production in human osteoarthritic synovial
tissue and cartilage cultures by aminoguanidine. Ann Rheum Dis.
60:391–394. 2001.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Farghaly HS and Thabit RH: L-arginine and
aminoguanidine reduce colonic damage of acetic acid-induced colitis
in rats: Potential modulation of nuclear factor-κB/p65. ClinExp
Pharmacol Physiol. 41:769–779. 2014.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Di Naso FC, Rodrigues G, Dias AS, Porawski
M, Fillmann H and Marroni NP: Hepatic nitrosative stress in
experimental diabetes. J Diabetes Complications. 26:378–381.
2012.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Wang J, Kalhor A, Lu S, Crawford R, Ni JD
and Xiao Y: iNOS expression and osteocyte apoptosis in idiopathic,
non-traumatic osteonecrosis. Acta Orthop. 86:131–141.
2015.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Kim J, Kim CS, Sohn E, Lee YM, Jo K, Shin
SD and Kim JS: Aminoguanidine protects against apoptosis of retinal
ganglion cells in Zucker diabetic fatty rats. Eur Rev Med Pharmacol
Sci. 18:1573–1578. 2014.PubMed/NCBI
|
|
13
|
Li W, Hu Q, Ren X, He P, Xu H, Dai H and
Chen Z: Aminoguanidine suppresses methylglyoxal-mediated
oxygen-glucose deprivation injury in human brain microvascular
endothelial cells. Zhejiang Da Xue Xue Bao Yi Xue Ban. 42:261–266.
2013.(In Chinese). PubMed/NCBI
|
|
14
|
Tian M, Qing C, Niu Y, Dong J, Cao X, Song
F, Ji X and Lu S: Effect of aminoguanidine intervention on
neutrophils in diabetes inflammatory cells wound healing. Exp Clin
Endocrinol Diabetes. 121:635–642. 2013.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Sliman SM, Eubank TD, Kotha SR, Kuppusamy
ML, Sherwani SI, Butler ES Kuppusamy P, Roy S, Marsh CB, Stern DM
and Parinandi NL: Hyperglycemic oxoaldehyde, glyoxal, causes
barrier dysfunction, cytoskeletal alterations, and inhibition of
angiogenesis in vascular endothelial cells: Aminoguanidine
protection. Mol Cell Biochem. 333:9–26. 2010.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Saiko P, Graser G, Giessrigl B, Lackner A,
Grusch M, Krupitza G, Basu A, Sinha BN, Jayaprakash V, Jaeger W, et
al: A novel N-hydroxy-N'-aminoguanidine derivative inhibits
ribonucleotide reductase activity: Effects in human HL-60
promyelocytic leukemia cells and synergism with
arabinofuranosylcytosine (Ara-C). Biochem Pharmacol. 81:50–59.
2011.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Zheng B, Zheng T, Wang L, Chen X, Shi C
and Zhao S: Aminoguanidine inhibition of iNOS activity ameliorates
cerebral vasospasm after subarachnoid hemorrhage in rabbits via
restoration of dysfunctional endothelial cells. J Neurol Sci.
295:97–103. 2010.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Berenbaum F: Osteoarthritis as an
inflammatory disease (osteoarthritis is not osteoarthrosis!).
Osteoarthritis Cartilage. 21:16–21. 2013.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Rigoglou S and Papavassiliou AG: The NF-κB
signalling pathway in osteoarthritis. Int J Biochem Cell Biol.
45:2580–2584. 2013.
|
|
20
|
Wojdasiewicz P, Poniatowski ŁA and
Szukiewicz D: The role of inflammatory and anti-inflammatory
cytokines in the pathogenesis of osteoarthritis. Mediators Inflamm.
2014(561459)2014.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Liao S, Zhou K, Li D, Xie X, Jun F and
Wang J: Schisantherin A suppresses interleukin-1β-induced
inflammation in human chondrocytes via inhibition of NF-κB and
MAPKs activation. Eur J Pharmacol. 780:65–70. 2016.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Rasheed N, Alghasham A and Rasheed Z:
Lactoferrin from camelus dromedarius inhibits nuclear transcription
factor-κB Activation, Cyclooxygenase-2 expression and prostaglandin
E2 production in stimulated human chondrocytes. Pharmacognosy Res.
8:135–141. 2016.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Zhuang Z, Ye G and Huang B: Kaempferol
alleviates the interleukin-1β-induced inflammation in rat
osteoarthritis chondrocytes via suppression of NF-κB. Med Sci
Monit. 23:3925–3931. 2017.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Chen YJ, Tsai KS, Chan DC, Lan KC, Chen
CF, Yang RS and Liu SH: Honokiol, a low molecular weight natural
product, prevents inflammatory response and cartilage matrix
degradation in human osteoarthritis chondrocytes. J Orthop Res.
32:573–580. 2014.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Zhou HF, Yan H, Pan H, Hou KK, Akk A,
Springer LE, Hu Y, Allen JS, Wickline SA and Pham C: Peptide-siRNA
nanocomplexes targeting NF-κB subunit p65 suppress nascent
experimental arthritis. J Clin Invest. 124:4363–4374.
2014.PubMed/NCBI View
Article : Google Scholar
|
|
26
|
Wang D, Qiao J, Zhao X, Chen T and Guan D:
Thymoquinone inhibits IL-1β-induced inflammation in human
osteoarthritis chondrocytes by suppressing NF-κB and MAPKs
signaling pathway. Inflammation. 38:2235–2241. 2015.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Li Y, Wang J, Song X, Bai H, Ma T, Zhang
Z, Li X, Jiang R, Wang G, Fan X, et al: Effects of baicalein on
IL-1β-induced inflammation and apoptosis in rat articular
chondrocytes. Oncotarget. 8:90781–90795. 2017.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Ahmad R, Ahmad N, Naqvi AA, Exarchou V,
Upadhyay A, Tuenter E, Foubert K, Apers S, Hermans N and Pieters L:
Antioxidant and Antiglycating Constituents from Leaves of Ziziphus
oxyphylla and Cedrela serrata. Antioxidants(Basel).
5(9)2016.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Orman D, Vardi N, Ates B, Taslidere E and
Elbe H: Aminoguanidine mitigates apoptosis, testicular seminiferous
tubules damage, and oxidative stress in streptozotocin-induced
diabetic rats. Tissue Cell. 47:284–290. 2015.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Wright C, Iyer AKV, Kulkarni Y and Azad N:
S-Nitrosylation of Bcl-2 negatively affects autophagy in lung
epithelial cells. J Cell Biochem. 117:521–532. 2015.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Madhu BP, Singh KP, Saminathan M, Singh R,
Tiwari AK, Manjunatha V, Harish C and Manjunathareddy GB:
Correlation of inducible nitric oxide synthase (iNOS) inhibition
with TNF-α, caspase-1, FasL and TLR-3 in pathogenesis of rabies in
mouse model. Virus Genes. 52:61–71. 2016.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Shafaroodi H, Hassanipour M, Mousavi Z,
Rahimi N and Dehpour AR: The effects of sub-chronic treatment with
pioglitazone on the septic mice mortality in the model of cecal
ligation and puncture: Involvement of nitric oxide pathway. Acta
Med Iran. 53:608–616. 2015.PubMed/NCBI
|
|
34
|
Tian M, Qing C, Niu Y, Dong J, Cao X, Song
F, Ji X and Lu S: Aminoguanidine cream ameliorates skin tissue
microenvironment in diabetic rats. Arch Med Sci. 12:179–187.
2016.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Parthasarathy A, Gopi V, Devi KMS, Balaji
N and Vellaichamy E: Aminoguanidine inhibits ventricular fibrosis
and remodeling process in isoproterenol-induced hypertrophied rat
hearts by suppressing ROS and MMPs. Life Sci. 118:15–26.
2014.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Lenin R, Mohan V and Balasubramanyam M:
SEAP activity serves for demonstrating ER stress induction by
glucolipotoxicity as well as testing ER stress inhibitory potential
of therapeutic agents. Mol Cell Biochem. 404:271–279.
2015.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Chen WP, Wang YL, Tang JL, Hu PF, Bao JP
and Wu LD: Morin inhibits interleukin-1β-induced nitric oxide and
prostaglandin E2 production in human chondrocytes. Int
Immunopharmacol. 12:447–452. 2012.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Li R, Cai L, Ding J, Hu CM, Wu TN and Hu
XY: Inhibition of hedgehog signal pathway by cyclopamine attenuates
inflammation and articular cartilage damage in rats with
adjuvant-induced arthritis. J Pharm Pharmacol. 67:963–971.
2015.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Lianxu C, Hongti J and Changlong Y:
NF-kappaBp65-specific siRNA inhibits expression of genes of COX-2,
NOS-2 and MMP-9 in rat IL-1beta-induced and TNF-alpha-induced
chondrocytes. Osteoarthritis Cartilage. 14:367–376. 2006.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Huang X, Pan Q, Mao Z, Zhang R, Ma X, Xi Y
and You H: Sinapic acid inhibits the IL-1 β-induced inflammation
via MAPK downregulation in rat chondrocytes. Inflammation.
41:562–568. 2018.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Ma Z, Wang Y, Piao T and Liu J:
Echinocystic acid inhibits IL-1β-induced COX-2 and iNOS expression
in human osteoarthritis chondrocytes. Inflammation. 39:543–549.
2016.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Ansari MY and Haqqi TM: Interleukin-1β
induced stress granules sequester COX-2 mRNA and regulates its
stability and translation in human OA chondrocytes. Sci Rep.
6(27611)2016.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Suschek CV, Schnorr O and Kolb-Bachofen V:
The role of NOS in chronic inflammatory processes in vivo: Is it
damage-promoting, protective, or active at all? Curr Mol Med.
4:763–775. 2004.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Gómez R, Scotece M, Conde J, Lopez V, Pino
J, Lago F, Gómez-Reino JJ and Gualillo O: Nitric oxide boosts TLR-4
mediated lipocalin 2 expression in chondrocytes. J Orthop Res.
31:1046–1052. 2013.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Flaherty RL, Owen M, Fagan-Murphy A,
Intabli H, Healy D, Patel A, Allen MC, Patel BA and Flint MS:
Glucocorticoids induce production of reactive oxygen
species/reactive nitrogen species and DNA damage through an iNOS
mediated pathway in breast cancer. Breast Cancer Res.
19(35)2017.PubMed/NCBI View Article : Google Scholar
|
|
46
|
Wang SN, Xie GP, Qin CH, Chen YR, Zhang
KR, Li X, Wu Q, Dong WQ, Yang J and Yu B: Aucubin prevents
interleukin-1 beta induced inflammation and cartilage matrix
degradation via inhibition of NF-κB signaling pathway in rat
articular chondrocytes. Int Immunopharmacol. 24:408–415.
2015.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Chin KY: The spice for joint inflammation:
Anti-inflammatory role of curcumin in treating osteoarthritis. Dove
Medical Press. 10:3029–3042. 2016.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Lei M, Wang JG, Xiao DM, Fan M, Wang DP,
Xiong JY, Chen Y, Ding Y and Liu SL: Resveratrol inhibits
interleukin 1β-mediated inducible nitric oxide synthase expression
in articular chondrocytes by activating SIRT1 and thereby
suppressing nuclear factor-κB activity. Eur J Pharmacol. 674:73–79.
2012.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Ying X, Chen X, Cheng S, Shen Y, Peng L
and Xu HZ: Piperine inhibits IL-β induced expression of
inflammatory mediators in human osteoarthritis chondrocyte. Int
Immunopharmacol. 17:293–299. 2013.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Stuhlmeier KM: The anti-rheumatic gold
salt aurothiomalate suppresses interleukin-1beta-induced hyaluronan
accumulation by blocking HAS1 transcription and by acting as a
COX-2 transcriptional repressor. J Biol Chem. 282:2250–2258.
2007.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Haseeb A, Khan NM, Ashruf OS and Haqqi TM:
A polyphenol-rich pomegranate fruit extract suppresses NF-κB and
IL-6 expression by blocking the activation of IKK and NIK in
primary human chondrocytes. Phytother Res. 31:778–782.
2017.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Zheng W, Tao Z, Cai L, Chen C, Zhang C,
Wang Q, Ying X, Hu W and Chen H: Chrysin attenuates IL-1β-induced
expression of inflammatory mediators by suppressing NF-κB in human
osteoarthritis chondrocytes. Inflammation. 40:1143–1154.
2017.PubMed/NCBI View Article : Google Scholar
|
