|
1
|
Livshits G, Popham M, Malkin I, Sambrook
PN, Macgregor AJ, Spector T and Williams FM: Lumbar disc
degeneration and genetic factors are the main risk factors for low
back pain in women: The UK Twin Spine Study. Ann Rheum Dis.
70:1740–1745. 2011.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Hurwitz EL, Randhawa K, Yu H, Cote P and
Haldeman S: The Global Spine care initiative: A summary of the
global burden of low back and neck pain studies. Eur Spine J.
27:796–801. 2018.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Gantenbein B, Illien-Jünger S, Chan SC,
Walser J, Haglund L, Ferguson SJ, Iatridis JC and Grad S: Organ
culture bioreactors-platforms to study human intervertebral disc
degeneration and regenerative therapy. Curr Stem Cell Res Ther.
10:339–352. 2015.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Xia K, Zhu J, Hua J, Gong Z, Yu C, Zhou X,
Wang J, Huang X, Yu W, Li L, et al: Intradiscal injection of
induced pluripotent stem cell-derived nucleus pulposus-like
cell-seeded polymeric microspheres promotes rat disc regeneration.
Stem Cells Int. 2019(6806540)2019.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Bendtsen M, Bünger CE, Zou X, Foldager C
and Jørgensen HS: Autologous stem cell therapy maintains vertebral
blood flow and contrast diffusion through the endplate in
experimental intervertebral disc degeneration. Spine (Phila Pa
1976). 36:E373–E379. 2011.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Rodriguez AG, Slichter CK, Acosta FL,
Rodriguez-Soto AE, Burghardt AJ, Majumdar S and Lotz JC: Human disc
nucleus properties and vertebral endplate permeability. Spine
(Phila Pa 1976). 36:512–520. 2011.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Yuan W, Che W, Jiang YQ, Yuan FL, Wang HR,
Zheng GL, Li XL and Dong J: Establishment of intervertebral disc
degeneration model induced by ischemic sub-endplate in rat tail.
Spine J. 15:1050–1059. 2015.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Colombier P, Clouet J, Hamel O, Lescaudron
L and Guicheux J: The lumbar intervertebral disc: From embryonic
development to degeneration. Joint Bone Spine. 81:125–129.
2014.PubMed/NCBI View Article : Google Scholar
|
|
9
|
He Z, Leong DJ, Xu L, Hardin JA, Majeska
RJ, Schaffler MB, Thi MM, Yang L, Goldring MB, Cobelli NJ and Sun
HB: CITED2 mediates the cross-talk between mechanical loading and
IL-4 to promote chondroprotection. Ann N Y Acad Sci. 1442:128–137.
2019.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Lu W, Cao F, Wang S, Sheng X and Ma J:
LncRNAs: The regulator of glucose and lipid metabolism in tumor
cells. Front Oncol. 9(1099)2019.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Wang H, Huo X, Yang XR, He J, Cheng L,
Wang N, Deng X, Jin H, Wang N, Wang C, et al: STAT3-mediated
upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer
metastasis by regulating SOX4. Mol Cancer. 16(136)2017.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Chen J, Liu A, Wang Z, Wang B, Chai X, Lu
W, Cao T, Li R, Wu M, Lu Z, et al: LINC00173.v1 promotes
angiogenesis and progression of lung squamous cell carcinoma by
sponging miR-511-5p to regulate VEGFA expression. Mol Cancer.
19(98)2020.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Wang K, Long B, Zhou LY, Liu F, Zhou QY,
Liu CY, Fan YY and Li PF: CARL lncRNA inhibits anoxia-induced
mitochondrial fission and apoptosis in cardiomyocytes by impairing
miR-539-dependent PHB2 downregulation. Nat Commun.
5(3596)2014.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Chen X, Yan CC, Zhang X and You ZH: Long
non-coding RNAs and complex diseases: From experimental results to
computational models. Brief Bionform. 18:558–576. 2017.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Chen X, Sun YZ, Guan NN, Qu J, Huang ZA,
Zhu ZX and Li JQ: Computational models for lncRNA function
prediction and functional similarity calculation. Brief Funct
Genomics. 18:58–82. 2019.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Kanehisa M, Furumichi M, Tanabe M, Sato Y
and Morishima K: KEGG: New perspectives on genomes, pathways,
diseases and drugs. Nucleic Acids Res. 45:D353–D361.
2017.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Mi H, Muruganujan A, Huang X, Ebert D,
Mills C, Guo X and Thomas PD: Protocol update for large-scale
genome and gene function analysis with the PANTHER classification
system (v.14.0). Nat Protoc. 14:703–721. 2019.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Yu G, Wang LG, Han Y and He QY:
clusterProfiler: An R package for comparing biological themes among
gene clusters. OMICS. 16:284–287. 2012.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Chen Y and Wang X: miRDB: An online
database for prediction of functional microRNA targets. Nucleic
Acids Res. 48:D127–D131. 2020.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Chou CH, Shrestha S, Yang CD, Chang NW,
Lin YL, Liao KW, Huang WC, Sun TH, Tu SJ, Lee WH, et al: miRTarBase
update 2018: A resource for experimentally validated
microRNA-target interactions. Nucleic Acids Res. 46:D296–D302.
2018.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Agarwal V, Bell GW, Nam JW and Bartel DP:
Predicting effective microRNA target sites in mammalian mRNAs.
Elife. 4(e05005)2015.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Shannon P, Markiel A, Ozier O, Baliga NS,
Wang JT, Ramage D, Amin N, Schwikowski B and Ideker T: Cytoscape: A
software environment for integrated models of biomolecular
interaction networks. Genome Res. 13:2498–2504. 2003.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
24
|
LaPointe VL, Verpoorte A and Stevens MM:
The changing integrin expression and a role for integrin β8 in the
chondrogenic differentiation of mesenchymal stem cells. PLoS One.
8(e82035)2013.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Guo L, Zhu Y, Li L, Zhou S, Yin G, Yu G
and Cui H: Breast cancer cell-derived exosomal miR-20a-5p promotes
the proliferation and differentiation of osteoclasts by targeting
SRCIN1. Cancer Med. 8:5687–5701. 2019.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Berg-Johansen B, Han M, Fields AJ,
Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug
R and Lotz JC: Cartilage endplate thickness variation measured by
ultrashort Echo-time MRI is associated with adjacent disc
degeneration. Spine (Phila Pa 1976). 43:E592–E600. 2018.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Zhang JF, Wang GL, Zhou ZJ, Fang XQ, Chen
S and Fan SW: Expression of matrix metalloproteinases, tissue
inhibitors of metalloproteinases, and interleukins in vertebral
cartilage endplate. Orthop Surg. 10:306–311. 2018.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Zhang Y, He F, Chen Z, Su Q, Yan M, Zhang
Q, Tan J, Qian L and Han Y: Melatonin modulates IL-1β-induced
extracellular matrix remodeling in human nucleus pulposus cells and
attenuates rat intervertebral disc degeneration and inflammation.
Aging (Albany NY). 11:10499–10512. 2019.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Xu T, Wu K and Zhang L, Zheng S, Wang X,
Zuo H, Wu X, Tao G, Jiang B and Zhang L: Long non-coding RNA
LINC00858 exerts a tumor-promoting role in colon cancer via
HNF4alpha and WNK2 regulation. Cell Oncol (Dordr). 43:297–310.
2019.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Liao C, Long Z, Zhang X, Cheng J, Qi F, Wu
S and Huang T: LncARSR sponges miR-129-5p to promote proliferation
and metastasis of bladder cancer cells through increasing SOX4
expression. Int J Biol Sci. 16:1–11. 2020.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Alanko J and Ivaska J: Endosomes: Emerging
platforms for integrin-mediated FAK signalling. Trends Cell Biol.
26:391–398. 2016.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Hirose N, Okamoto Y, Yanoshita M, Asakawa
Y, Sumi C, Takano M, Nishiyama S, Su SC, Mitsuyoshi T, Kunimatsu R,
et al: Protective effects of cilengitide on inflammation in
chondrocytes under excessive mechanical stress. Cell Biol Int.
44:966–974. 2020.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Yan Z, Pan Y, Wang S, Cheng M, Kong H, Sun
C, Hu K, Chen T, Dong Q and Chen J: Static Compression induces ECM
remodeling and integrin α2β1 expression and signaling in a rat tail
caudal intervertebral disc degeneration model. Spine (Phila Pa
1976). 42:E448–E458. 2017.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Almonte-Becerril M, Gimeno LI, Villarroya
O, Benito-Jardon M, Kouri JB and Costell M: Genetic abrogation of
the fibronectin-α5β1 integrin interaction in articular cartilage
aggravates osteoarthritis in mice. PLoS One.
13(e0198559)2018.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Li XF, Xue CC, Zhao YJ, Cheng SD, Zhao DF,
Liang QQ, Chen L, Wang Q, Lu S, Shi Q, et al: Deletion of Opg leads
to increased neovascularization and expression of inflammatory
cytokines in the lumbar intervertebral disc of mice. Spine (Phila
Pa 1976). 42:E8–E14. 2017.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Qu Z, Quan Z, Zhang Q, Wang Z, Song Q,
Zhuang X, Fu C, Xu F, Liu Y, Wang Y, et al: Comprehensive
evaluation of differential lncRNA and gene expression in patients
with intervertebral disc degeneration. Mol Med Rep. 18:1504–1512.
2018.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Xue H, Yu P, Wang WZ, Niu YY and Li X: The
reduced lncRNA NKILA inhibited proliferation and promoted apoptosis
of chondrocytes via miR-145/SP1/NF-κB signaling in human
osteoarthritis. Eur Rev Med Pharmacol Sci. 24:535–548.
2020.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Gu HY, Yang M, Guo J, Zhang C, Lin LL, Liu
Y and Wei RX: Identification of the biomarkers and pathological
process of osteoarthritis: Weighted Gene Co-expression network
analysis. Front Physiol. 10(275)2019.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Xue H, Tu Y, Ma T, Liu X, Wen T, Cai M,
Xia Z and Mei J: Lactoferrin inhibits IL-1β-induced chondrocyte
apoptosis through AKT1-induced CREB1 activation. Cell Physiol
Biochem. 36:2456–2465. 2015.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Nishimura R, Hata K, Matsubara T,
Wakabayashi M and Yoneda T: Regulation of bone and cartilage
development by network between BMP signalling and transcription
factors. J Biochem. 151:247–254. 2012.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Sideek MA, Menz C, Parsi MK and Gibson MA:
LTBP-2 competes with tropoelastin for binding to fibulin-5 and
heparin, and is a negative modulator of elastinogenesis. Matrix.
34:114–123. 2014.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Goessler UR, Bugert P, Bieback K, Deml M,
Sadick H, Hormann K and Riedel F: In-vitro analysis of the
expression of TGFbeta-superfamily-members during chondrogenic
differentiation of mesenchymal stem cells and chondrocytes during
dedifferentiation in cell culture. Cell Mol Biol Lett. 10:345–362.
2005.PubMed/NCBI
|
|
43
|
Wei T, Kulkarni NH, Zeng QQ, Helvering LM,
Lin X, Lawrence F, Hale L, Chambers MG, Lin C, Harvey A, et al:
Analysis of early changes in the articular cartilage
transcriptisome in the rat meniscal tear model of osteoarthritis:
Pathway comparisons with the rat anterior cruciate transection
model and with human osteoarthritic cartilage. Osteoarthr Cartil.
18:992–1000. 2010.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Weimer A, Madry H, Venkatesan JK, Schmitt
G, Frisch J, Wezel A, Jung J, Kohn D, Terwilliger EF, Trippel SB
and Cucchiarini M: Benefits of recombinant adeno-associated virus
(rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression
for the long-term reconstruction of human osteoarthritic cartilage
by modulation of the IGF-I axis. Mol Med. 18:346–358.
2012.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Hu Y, Wu R, Li H, Gu Y and Wei W:
Expression and significance of metalloproteinase and collagen in
vaginal wall tissues of patients with pelvic organ prolapse. Ann
Clin Lab Sci. 47:698–705. 2017.PubMed/NCBI
|
|
46
|
Willard K, Mannion S, Saunders CJ, Collins
M and September AV: The interaction of polymorphisms in
extracellular matrix genes and underlying miRNA motifs that
modulate susceptibility to anterior cruciate ligament rupture. J
Sci Med Sport. 21:22–28. 2018.PubMed/NCBI View Article : Google Scholar
|
|
47
|
Wu JJ, Weis MA, Kim LS, Carter BG and Eyre
DR: Differences in chain usage and cross-linking specificities of
cartilage type V/XI collagen isoforms with age and tissue. J Biol
Chem. 284:5539–5545. 2009.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Zhou S, Wang Z, Tang J, Li W, Huang J, Xu
W, Luo F, Xu M, Wang J, Wen X, et al: Exogenous fibroblast growth
factor 9 attenuates cartilage degradation and aggravates osteophyte
formation in post-traumatic osteoarthritis. Osteoarthritis
Cartilage. 24:2181–2192. 2016.PubMed/NCBI View Article : Google Scholar
|
|
49
|
Song EK, Jeon J, Jang DG, Kim HE, Sim HJ,
Kwon KY, Medina-Ruiz S, Jang HJ, Lee AR, Rho JG, et al: ITGBL1
modulates integrin activity to promote cartilage formation and
protect against arthritis. Sci Transl Med.
10(eaam7486)2018.PubMed/NCBI View Article : Google Scholar
|
|
50
|
Choocheep K, Hatano S, Takagi H and
Watanabe H, Kimata K, Kongtawelert P and Watanabe H: Versican
facilitates chondrocyte differentiation and regulates joint
morphogenesis. J Biol Chem. 285:21114–21125. 2010.PubMed/NCBI View Article : Google Scholar
|
|
51
|
Yang L, Clinton JM, Blackburn ML, Zhang Q,
Zou J, Zielinska-Kwiatkowska A, Tang BL and Chansky HA: Rab23
regulates differentiation of ATDC5 chondroprogenitor cells. J Biol
Chem. 283:10649–10657. 2008.PubMed/NCBI View Article : Google Scholar
|
|
52
|
Randall RM, Shao YY, Wang L and Ballock
RT: Activation of Wnt planar cell polarity (PCP) signaling promotes
growth plate column formation in vitro. J Orthop Res. 30:1906–1914.
2012.PubMed/NCBI View Article : Google Scholar
|
|
53
|
Chen Y, Wang X, Yang M, Ruan W, Wei W, Gu
D, Wang J, Guo X, Guo L and Yuan Y: miR-145-5p Increases osteoclast
numbers in vitro and aggravates bone erosion in collagen-induced
arthritis by targeting osteoprotegerin. Med Sci Monit.
24:5292–5300. 2018.PubMed/NCBI View Article : Google Scholar
|
|
54
|
Xiao ZF, He JB, Su GY, Chen MH, Hou Y,
Chen SD and Lin DK: Osteoporosis of the vertebra and osteochondral
remodeling of the endplate causes intervertebral disc degeneration
in ovariectomized mice. Arthritis Res. 20(207)2018.PubMed/NCBI View Article : Google Scholar
|
|
55
|
Hu J, Wang Z, Shan Y, Pan Y, Ma J and Jia
L: Long non-coding RNA HOTAIR promotes osteoarthritis progression
via miR-17-5p/FUT2/β-catenin axis. Cell Death Dis.
9(711)2018.PubMed/NCBI View Article : Google Scholar
|
|
56
|
Xue H, Tu Y, Ma T, Wen T, Yang T, Xue L,
Cai M, Wang F and Guan M: miR-93-5p attenuates IL-1β-induced
chondrocyte apoptosis and cartilage degradation in osteoarthritis
partially by targeting TCF4. Bone. 123:129–136. 2019.PubMed/NCBI View Article : Google Scholar
|
|
57
|
Wang C, Xu X, Chen J, Kang Y, Guo J,
Duscher D, Yang X, Guo G, Ren S, Xiong H, et al: The construction
and analysis of lncRNA-miRNA-mRNA competing endogenous RNA network
of Schwann cells in diabetic peripheral neuropathy. Front Bioeng
Biotechnol. 8(490)2020.PubMed/NCBI View Article : Google Scholar
|
|
58
|
Zhang S, Chang YY, Gong YW, Gao YJ, Guo Q,
Wang YH, Zhao YL and Wang ZP: Comprehensive analysis of
microRNA-messenger RNA regulatory network in gemcitabine-resistant
bladder cancer cells. J Cell Biochem. 120:6347–6360.
2019.PubMed/NCBI View Article : Google Scholar
|
|
59
|
Cao M, Zhang L, Wang JH, Zeng H, Peng Y,
Zou J, Shi J, Zhang L, Li Y, Yoshida S, et al: Identifying
circRNA-associated-ceRNA networks in retinal neovascularization in
mice. Int J Med Sci. 16:1356–1365. 2019.PubMed/NCBI View Article : Google Scholar
|
|
60
|
Wang S, Zhan J, Lin X, Wang Y, Wang Y and
Liu Y: CircRNA-0077930 from hyperglycaemia-stimulated vascular
endothelial cell exosomes regulates senescence in vascular smooth
muscle cells. Cell Biochem Funct: Apr 19 doi: 10.1002/cbf.3543.2020
(Epub ahead of print).
|
|
61
|
Wang R, Zhang S, Chen X, Li N, Li J, Jia
R, Pan Y and Liang H: EIF4A3-induced circular RNA MMP9 (circMMP9)
acts as a sponge of miR-124 and promotes glioblastoma multiforme
cell tumorigenesis. Mol Cancer. 17(166)2018.PubMed/NCBI View Article : Google Scholar
|
|
62
|
Gao A, Gong Y, Zhu C, Yang W, Li Q, Zhao
M, Ma S, Li J, Hao S, Cheng H and Cheng T: Bone marrow endothelial
cell-derived interleukin-4 contributes to thrombocytopenia in acute
myeloid leukemia. Haematologica. 104:1950–1961. 2019.PubMed/NCBI View Article : Google Scholar
|
|
63
|
Zhao X, Li D, Yang F, Lian H, Wang J, Wang
X, Fang E, Song H, Hu A, Guo Y, et al: Long noncoding RNA NHEG1
drives β-catenin transactivation and neuroblastoma progression
through interacting with DDX5. Mol Ther. 28:946–962.
2020.PubMed/NCBI View Article : Google Scholar
|
|
64
|
Chen X and Yan G: Novel human
lncRNA-disease association inference based on lncRNA expression
profiles. Bioinformatics. 29:2617–2624. 2013.PubMed/NCBI View Article : Google Scholar
|
|
65
|
Herszage J and Censor N: Modulation of
learning and memory: A shared framework for interference and
generalization. Neuroscience. 392:270–280. 2018.PubMed/NCBI View Article : Google Scholar
|
|
66
|
Gershman SJ and Daw ND: Reinforcement
learning and episodic memory in humans and animals: An integrative
framework. Annu Rev Psychol. 68:101–128. 2017.PubMed/NCBI View Article : Google Scholar
|
