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Clinical and computed tomography features in patients with coronavirus disease 2019

  • Authors:
    • Dongxu Wang
    • Yuguang Wang
    • Qing Zhang
    • Baiming Jin
    • Qiuting  Wen
    • Fengxia Du
    • Jun He
    • Tianyu Zhang
    • Bo Li
    • Guoxu Ding
  • View Affiliations / Copyright

    Affiliations: Department of CT Diagnosis, The Second Affiliated Hospital of Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China, Department of Infectious Diseases, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China, Department of School of Public Health, Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China, Department of Pathology, Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China, Department of Microbiology, Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China, Department of Anatomy, Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China, Party Committee Office, The Second Affiliated Hospital of Qiqihar Medical College, Qiqihar, Heilongjiang 161006, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 129
    |
    Published online on: December 10, 2020
       https://doi.org/10.3892/etm.2020.9561
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Abstract

Coronavirus disease 2019 (COVID‑19) has recently broken out in China. To describe the clinical and computed tomography (CT) characteristics in patients with COVID‑19‑induced pneumonia, the current study retrospectively analyzed the data of 152 patients with pneumonia between December 30, 2019 and February 29, 2020. Pharyngeal swabs for nucleic acid detection of respiratory secretions were used for all patients. A total of 65 cases were diagnosed as COVID‑19, and 87 cases were non‑COVID‑19. When comparing the clinical and CT characteristics of the two groups of patients, only sex and history of exposure presented a statistically significant difference. The normal/low white blood cell count, low lymphocyte ratio and high C‑reactive protein (CRP) exhibited a statistically significant difference between the two groups. A total of 62 patients in the COVID‑19 group exhibited ground‑glass opacity (GGO), which was higher than that in the non‑COVID‑19 group. In the COVID‑19 group, 33 cases presented angiographic thickening in GGO, and 27 cases displayed a paving stone sign, which were higher than those in the non‑COVID‑19 group. Compared with the non‑COVID‑19 group, the lesions in the COVID‑19 group were principally characterized by bilateral lungs, multifocal and subpleural distribution. The results of the present study revealed that when the male patients with contact history in the epidemic area exhibited fever and cough symptoms, the laboratory tests indicated normal/low white blood cell counts, low lymphocyte ratios and elevated CRP levels. CT scans were recommended for subsequent examination. GGO or GGO and consolidation with bilateral lungs were indicated to be primarily distributed in the multifocal subpleural area and were accompanied by angiographic thickening in GGO and paving stone sign. In conclusion, regardless of whether the viral nucleic acid test is positive, COVID‑19 should be considered for medical treatment observation in isolation.
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Copy and paste a formatted citation
Spandidos Publications style
Wang D, Wang Y, Zhang Q, Jin B, Wen Q, Du F, He J, Zhang T, Li B, Ding G, Ding G, et al: Clinical and computed tomography features in patients with coronavirus disease 2019. Exp Ther Med 21: 129, 2021.
APA
Wang, D., Wang, Y., Zhang, Q., Jin, B., Wen, Q., Du, F. ... Ding, G. (2021). Clinical and computed tomography features in patients with coronavirus disease 2019. Experimental and Therapeutic Medicine, 21, 129. https://doi.org/10.3892/etm.2020.9561
MLA
Wang, D., Wang, Y., Zhang, Q., Jin, B., Wen, Q., Du, F., He, J., Zhang, T., Li, B., Ding, G."Clinical and computed tomography features in patients with coronavirus disease 2019". Experimental and Therapeutic Medicine 21.2 (2021): 129.
Chicago
Wang, D., Wang, Y., Zhang, Q., Jin, B., Wen, Q., Du, F., He, J., Zhang, T., Li, B., Ding, G."Clinical and computed tomography features in patients with coronavirus disease 2019". Experimental and Therapeutic Medicine 21, no. 2 (2021): 129. https://doi.org/10.3892/etm.2020.9561
Copy and paste a formatted citation
x
Spandidos Publications style
Wang D, Wang Y, Zhang Q, Jin B, Wen Q, Du F, He J, Zhang T, Li B, Ding G, Ding G, et al: Clinical and computed tomography features in patients with coronavirus disease 2019. Exp Ther Med 21: 129, 2021.
APA
Wang, D., Wang, Y., Zhang, Q., Jin, B., Wen, Q., Du, F. ... Ding, G. (2021). Clinical and computed tomography features in patients with coronavirus disease 2019. Experimental and Therapeutic Medicine, 21, 129. https://doi.org/10.3892/etm.2020.9561
MLA
Wang, D., Wang, Y., Zhang, Q., Jin, B., Wen, Q., Du, F., He, J., Zhang, T., Li, B., Ding, G."Clinical and computed tomography features in patients with coronavirus disease 2019". Experimental and Therapeutic Medicine 21.2 (2021): 129.
Chicago
Wang, D., Wang, Y., Zhang, Q., Jin, B., Wen, Q., Du, F., He, J., Zhang, T., Li, B., Ding, G."Clinical and computed tomography features in patients with coronavirus disease 2019". Experimental and Therapeutic Medicine 21, no. 2 (2021): 129. https://doi.org/10.3892/etm.2020.9561
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