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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February-2021 Volume 21 Issue 2

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Article

BAY11‑7082 inhibits the expression of tissue factor and plasminogen activator inhibitor‑1 in type‑II alveolar epithelial cells following TNF‑α stimulation via the NF‑κB pathway

Yumei Cheng, Bo Liu, Hong Qian, Huilin Yang, Yahui Wang, Yanqi Wu, Feng Shen
Article Number: 177
Published online on: 28 December 2020

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Review Open Access

Risk factors and prevention strategies for the occupational exposure of medical staff during the coronavirus disease‑19 pandemic (Review)

Jin Tang, Ying Li, Qilin Lu, Wei Xie, Shijing Zhou, Yanling Liu, Qingchun Zeng, Xugui Li
Article Number: 176
Published online on: 28 December 2020

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Article Open Access

ACTL6A knockdown inhibits cell migration by suppressing the AKT signaling pathway and enhances the sensitivity of glioma cells to temozolomide

Xueru Chen, Zijin Xiang, Dangchi Li, Xiuting Zhu, Xiangdong Peng
Article Number: 175
Published online on: 28 December 2020

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Article Open Access

A retrospective study on the evaluation of the symptoms, medications and improvement of the quality of life of patients undergoing robotic surgery for gastroesophageal reflux disease

Sofia K. Konstantinidou, Penelope Kostaras, Georgios-Eleftherios Anagnostopoulos, Sophia-Liberty Markantonis, Vangelis Karalis, Konstantinos Konstantinidis
Article Number: 174
Published online on: 27 December 2020

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Review Open Access

Role of TRPM7 in cardiac fibrosis: A potential therapeutic target (Review)

Feng Hu, Meiyong Li, Fengyu Han, Qing Zhang, Yuhao Zeng, Weifang Zhang, Xiaoshu Cheng
Article Number: 173
Published online on: 27 December 2020

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Article Open Access

Ultrasonography‑assisted flexible ureteroscope for the treatment of parapelvic renal cysts: A comparison between the 1470‑nm diode laser and the holmium laser

Yu Chen, Rongjiang Wang, Xufeng Shen, Jianer Tang, Junwen Shen, Zhihai Fang, Zhanqin Shi, Xiaodong Jin
Article Number: 172
Published online on: 27 December 2020

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Article Open Access

MicroRNA‑140‑5p regulates the proliferation, apoptosis and inflammation of RA FLSs by repressing STAT3

Jiehua Zhu, Jianglin Wang, Jialin Huang, Wensheng Du, Yingzhong He, Hongfei Pan, Junmin Luo
Article Number: 171
Published online on: 27 December 2020

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Article Open Access

Network analysis and transcriptome profiling in peripheral blood mononuclear cells of patients with rheumatoid arthritis

Yan Long, Jian Liu, Hui Jiang, Ling Xin, Lei Wan, Yue Sun, Pingheng Zhang, Jianting Wen, Dan Huang, Yanqiu Sun, Ying Zhang, Bingxi Bao, Guanghan Sun
Article Number: 170
Published online on: 25 December 2020

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Article Open Access

HBV induces liver fibrosis via the TGF‑β1/miR‑21‑5p pathway

Wenting Li, Xiaolan Yu, Xiliu Chen, Zheng Wang, Ming Yin, Zonghao Zhao, Chuanwu Zhu
Article Number: 169
Published online on: 25 December 2020

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Article Open Access

Influence of aging on the peripheral nerve repair process using an artificial nerve conduit

Ayaka Kaneko, Kiyohito Naito, Shinji Nakamura, Katsumi Miyahara, Kenji Goto, Hiroyuki Obata, Nana Nagura, Yoichi Sugiyama, Kazuo Kaneko, Muneaki Ishijima
Article Number: 168
Published online on: 21 December 2020

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Article

Association of oral HPV16 infection with periodontal inflammation and the oral microbiome in older women

Hideo Shigeishi, Cheng-Yih Su, Yoshino Kaneyasu, Mari Matsumura, Mariko Nakamura, Momoko Ishikawa, Ayumi Saito, Kouji Ohta, Masaru Sugiyama
Article Number: 167
Published online on: 21 December 2020

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Article

Recombinant laminin α5 LG1-3 domains support the stemness of human mesenchymal stem cells

Sujin Lee, Dong-Sung Lee, Jun-Hyeog Jang
Article Number: 166
Published online on: 21 December 2020

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Article Open Access

The neuroprotective effects of pregabalin after cerebral ischemia by occlusion of the middle cerebral artery in rats

Junekyung Lee, Chang Gu Kang, Chae Ri Park, In Kyung Hong, Dae Yul Kim
Article Number: 165
Published online on: 21 December 2020

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Article Open Access

Accuracy of 18F‑FDG PET/CT and CECT for primary staging and diagnosis of recurrent gastric cancer: A meta‑analysis

Zhicheng Zhang, Bo Zheng, Wei Chen, Hui Xiong, Caiming Jiang
Article Number: 164
Published online on: 21 December 2020

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Article Open Access

Inflammatory signals induce MUC16 expression in ovarian cancer cells via NF‑κB activation

Jie Liu, Li Li, Ning Luo, Qi Liu, Li Liu, Dandan Chen, Zhongping Cheng, Xiaowei Xi
Article Number: 163
Published online on: 21 December 2020

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Article Open Access

Difference in serum miRNA expression between immunoglobulin‑sensitive and ‑insensitive incomplete Kawasaki disease patients

Yan Wang, Chunli Li, Ling Niu, Mingyu Fu, Jing Tian, Xinjiang An
Article Number: 162
Published online on: 18 December 2020

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Article

Association between IL‑33 and other inflammatory factors in patients with rheumatoid arthritis and in fibroblast‑like synoviocytes in vitro

Jing Wu, Qiang Li, Jiaxin Deng, Jin-Jun Zhao, Qing-Hong Yu
Article Number: 161
Published online on: 18 December 2020

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Article Open Access

Investigating the efficacy and safety of mineral smectite granules on wound healing

Jiankun Wang, Min Wang, Lili Zhao, Li Liu, Xiang Wang, Zhining Fan
Article Number: 160
Published online on: 18 December 2020

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Review Open Access

Pancreatic pseudocyst: Dilemma of its recent management (Review)

Jonathan Hartanto Tan, Wenjie Chin, Abdul Lateef Shaikh, Shusen Zheng
Article Number: 159
Published online on: 18 December 2020

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Article Open Access

Reciprocal regulation of interleukin‑17A and interleukin‑22 secretion through aryl hydrocarbon receptor activation in CD4+ T cells of patients with vitiligo

Baoyi Liu, Yongyi Xie, Xingyu Mei, Yue Sun, Weimin Shi, Zhouwei Wu
Article Number: 158
Published online on: 17 December 2020

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Article

DUOX2 participates in skin aging induced by UVB in HSF2 cells by activating NF‑κB signaling

Xiaoqing Xiao, Minghuan Huang, Chunyan Fan, Fuguo Zuo
Article Number: 157
Published online on: 17 December 2020

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Article Open Access

Differences in efficacy and safety of midazolam vs. dexmedetomidine in critically ill patients: A meta‑analysis of randomized controlled trial

Wen-Jun Zhou, Mei Liu, Xue-Peng Fan
Article Number: 156
Published online on: 17 December 2020

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Review Open Access

Confronting the threat of SARS‑CoV‑2: Realities, challenges and therapeutic strategies (Review)

Ruixue Wang, Xiaoshan Luo, Fang Liu, Shuhong Luo
Article Number: 155
Published online on: 17 December 2020

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Article Open Access

Unexplored regulatory sequences of divergently paired GLA and HNRNPH2 loci pertinent to Fabry disease in human kidney and skin cells: Presence of an active bidirectional promoter

Mohammed A. Ibrahim Al-Obaide, Ibtisam I. Al-Obaidi, Tetyana L. Vasylyeva
Article Number: 154
Published online on: 17 December 2020

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Article Open Access

Exercise reduces hyperlipidemia‑induced kidney damage in apolipoprotein E‑deficient mice

Chengsi Qian, Qin Yang, Lipeng Guo, Hupei Zhu, Xi You, Hongyang Liu, Yan Sun
Article Number: 153
Published online on: 17 December 2020

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Article Open Access

MicroRNA-490-3p inhibits inflammatory responses in LPS-induced acute lung injury of neonatal rats by suppressing the IRAK1/TRAF6 pathway

Guang Yang, Yuan Zhao
Article Number: 152
Published online on: 17 December 2020

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Article Open Access

Inhibitory effect of isomorellin on cholangiocarcinoma cells via suppression of NF-κB translocation, the phosphorylated p38 MAPK pathway and MMP-2 and uPA expression

Chariya Hahnvajanawong, Thitiporn Sahakulboonyarak, Thidarut Boonmars, Vichai Reutrakul, Anusak Kerdsin, Parichart Boueroy
Article Number: 151
Published online on: 17 December 2020

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Article Open Access

The circRNA_102911/miR‑129‑5p/SOX6 axis is involved with T lymphocyte immune function in elderly patients with laparoscopic left hepatectomy for hepatolithiasis

Hongqiang Zhao, Xiaoyu Shao, Haorun Liu, Qi Liu, Jiangyang Lu, Weimin Li
Article Number: 150
Published online on: 17 December 2020

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Article

Expression and significance of S‑100β, CysC and NF‑κB in patients with acute cerebral infarction

Zaili Li, Zaie Xin
Article Number: 149
Published online on: 16 December 2020

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Review

New progress in the treatment of neuromyelitis optica spectrum disorder with monoclonal antibodies (Review)

Qinfang Xie, Mengjiao Sun, Jing Sun, Ting Zheng, Manxia Wang
Article Number: 148
Published online on: 16 December 2020

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Article Open Access

Toxicity of the acetyl‑para‑aminophenol group of medicines to intact intervertebral disc tissue cells

Numan Karaarslan, Ibrahi̇m Yilmaz, Duygu Yasar Sirin
Article Number: 147
Published online on: 16 December 2020

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Article Open Access

Role of miRNAs and lncRNAs in dexamethasone‑induced myotube atrophy in vitro

Yang Li, Huacai Shi, Rui Chen, Shanyao Zhou, Si Lei, Yanling She
Article Number: 146
Published online on: 16 December 2020

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Article Open Access

Diagnostic value of candidate noncoding RNAs in leukocytes of patients with gestational diabetes mellitus

Jialei Hu, Hanyou Mu, Linshan Gao, Ying Pan, Chuanfei Wu, Dong Zhang, Qiaojun Chen, Honghui Ding
Article Number: 145
Published online on: 16 December 2020

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Article Open Access

Investigation of the natural supplement IQP‑AS‑119 for the prevention of upper respiratory tract infections in marathon race participants: A randomized, double‑blind, placebo‑controlled pilot study

Udo Bongartz, Uwe Hochmann, Ute Pohl, Gordana Bothe, Patricia De Costa, Pee-Win Chong, Lynette Chew, Ralf Uebelhack
Article Number: 144
Published online on: 16 December 2020

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Correction Open Access

[Corrigendum] Cardioprotective effects of triiodothyronine supplementation against ischemia reperfusion injury by preserving calcium cycling proteins in isolated rat hearts

Lichao Fang, Zhiping Xu, Jian Lu, Lei Hong, Shigang Qiao, Lijun Liu, Jianzhong An
Article Number: 143
Published online on: 16 December 2020

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Article Open Access

Identification of thrombomodulin as a dynamic monitoring biomarker for deep venous thrombosis evolution

Xi Cheng, Baolan Sun, Shiyi Liu, Dandan Li, Xiaoqing Yang, Yuquan Zhang
Article Number: 142
Published online on: 14 December 2020

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Article Open Access

4-Octyl itaconate (4-OI) attenuates lipopolysaccharide-induced acute lung injury by suppressing PI3K/Akt/NF-κB signaling pathways in mice

Yan Xin, Lili Zou, Shuhui Lang
Article Number: 141
Published online on: 14 December 2020

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Article Open Access

Risk factors of contrast‑induced nephropathy in patients with STEMI and pump failure undergoing percutaneous coronary intervention

Hongwu Chen, Xiaofan Yu, Likun Ma
Article Number: 140
Published online on: 14 December 2020

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Article Open Access

Adipose‑derived mesenchymal stem cells inhibit cell proliferation and migration and suppress extracellular matrix synthesis in hypertrophic‑scar and keloid fibroblasts

Fang Xie, Li Teng, Jiajie Xu, Jianjian Lu, Chao Zhang, Liya Yang, Xiaoyang Ma, Minghao Zhao
Article Number: 139
Published online on: 14 December 2020

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Article Open Access

Cystic fibrosis transmembrane conductance regulator in follicular fluid and cumulus cells and its relationship with age

Yanqiu Wang, Hui Wei, Yazhong Ji, Feiping Liu, Zhijun Shen, Xunyi Zhang
Article Number: 138
Published online on: 14 December 2020

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Article

Cholinergic receptors play a role in the cardioprotective effects of anesthetic preconditioning: Roles of nitric oxide and the CaMKKβ/AMPK pathway

Yang Yang, Ying Li, Jie Wang, Lei Hong, Shigang Qiao, Chen Wang, Jianzhong An
Article Number: 137
Published online on: 14 December 2020

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Article Open Access

Syngeneic homograft of framework regions enhances the affinity of the mouse anti‑human epidermal receptor 2 single‑chain antibody e23sFv

Qing Ou‑Yang, Jun-Lin Ren, Bo Yan, Jian-Nan Feng, An-Gang Yang, Jing Zhao
Article Number: 136
Published online on: 14 December 2020

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Article

Preventing oxaliplatin‑induced neuropathic pain: Using berberine to inhibit the activation of NF‑κB and release of pro‑inflammatory cytokines in dorsal root ganglions in rats

Wan Ni, Xiaolan Zheng, Ling Hu, Chao Kong, Qingbang Xu
Article Number: 135
Published online on: 10 December 2020

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Article Open Access

Poly(ADP‑ribose) polymerase‑1 inhibitor ameliorates dextran sulfate sodium‑induced colitis in mice by regulating the balance of Th17/Treg cells and inhibiting the NF‑κB signaling pathway

Shuai Peng, Lei Shen, Min-Xiu Tian, Hui-Min Li, Shan-Shan Wang
Article Number: 134
Published online on: 10 December 2020

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Article

Crosstalk between phosphorylation and ubiquitination is involved in high salt-induced WNK4 expression

Xiaoyue Zhao, Guangrui Lai, Jianqiao Tu, Shuchang Liu, Yanyan Zhao
Article Number: 133
Published online on: 10 December 2020

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Article Open Access

Dexmedetomidine at a dose of 1 µM attenuates H9c2 cardiomyocyte injury under 3 h of hypoxia exposure and 3 h of reoxygenation through the inhibition of endoplasmic reticulum stress

Zhipeng Zhu, Xiaoyan Ling, Hongmei Zhou, Caijun Zhang
Article Number: 132
Published online on: 10 December 2020

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Article Open Access

Role of lncRNA PART1 in intervertebral disc degeneration and associated underlying mechanism

Zongyu Zhang, Yongfeng Huo, Zhijing Zhou, Peng Zhang, Jun Hu
Article Number: 131
Published online on: 10 December 2020

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Article Open Access

Exercise electrocardiography combined with stress echocardiography for predicting myocardial ischemia in adults

Qiong Huang, Junhong Wang, Dianfu Li, Jihong  Zhao, Xiangjun Feng, Ningtian Zhou
Article Number: 130
Published online on: 10 December 2020

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Article Open Access

Clinical and computed tomography features in patients with coronavirus disease 2019

Dongxu Wang, Yuguang Wang, Qing Zhang, Baiming Jin, Qiuting  Wen, Fengxia Du, Jun He, Tianyu Zhang, Bo Li, Guoxu Ding
Article Number: 129
Published online on: 10 December 2020

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Article Open Access

Silencing GnT‑V reduces oxaliplatin chemosensitivity in human colorectal cancer cells through N‑glycan alteration of organic cation transporter member 2

Xi Cong, Xingwan Liu, Xiaopeng Dong, Shuoshuo Fang, Zheng Sun, Jianhui Fan
Article Number: 128
Published online on: 07 December 2020

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Article Open Access

Increased mortality in the A/A genotype of the SNP rs28372698 of interleukin 32

Urban Alehagen, Levar Shamoun, Jan Ingvar Dimberg, Dick Wågsäter
Article Number: 127
Published online on: 07 December 2020

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Article Open Access

Curcumin prevents renal cell apoptosis in acute kidney injury in a rat model of dry‑heat environment heatstroke via inhibition of the mitochondrial apoptotic pathway

Yin-Hui Zhao, Cai-Fu Shen, Yan Kang, Ao Qi, Wen-Juan Xu, Wen-Hui Shi, Jiang-Wei Liu
Article Number: 126
Published online on: 04 December 2020

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Article Open Access

Potential use of glutathione as a treatment for Parkinson's disease

Hai-Li Wang, Jun Zhang, Yu-Ping Li, Lun Dong, Ying-Zhu Chen
Article Number: 125
Published online on: 04 December 2020

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Article Open Access

A novel mutation in the RS1 gene in a Chinese family with X‑linked congenital retinoschisis

Na Zhang, Yao Peng, Nan Zhou, Yanhua Qi
Article Number: 124
Published online on: 03 December 2020

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Article Open Access

Prognostic nutritional index predicts acute kidney injury and mortality of patients in the coronary care unit

Yugang Hu, Quan Cao, Hao Wang, Yuanting Yang, Ye Xiong, Xiaoning Li, Qing Zhou
Article Number: 123
Published online on: 03 December 2020

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Article Open Access

Proteomic and microRNA‑omic profiles and potential mechanisms of dysfunction in pancreatic islet cells primed by inflammation

Yipei Ding, Jin Zhong, Yangyang Wang, Weidong Xie
Article Number: 122
Published online on: 03 December 2020

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Article Open Access

Evaluation of interpretation methods to improve accuracy of the prenatal BACs‑on‑Beads™ assay in prenatal diagnosis

Yu Jiang, Jian Zhang, Lili Wu, Wenbo Wang, Qiwei Guo
Article Number: 121
Published online on: 03 December 2020

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Article Open Access

Identification of miR-4793-3p as a potential biomarker for bacterial infection in patients with hepatitis B virus-related liver cirrhosis: A pilot study

Shenglong Lin, Minghua Lin, Huaxi Ma, Xiangmei Wang, Dongqing Zhang, Wenjun Wu, Jiahuang Lin, Haibing Gao
Article Number: 120
Published online on: 03 December 2020

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Article Open Access

Tetrandrine attenuates left ventricular dysfunction in rats with myocardial infarction

Youyang Wu, Wei Zhao, Fanhao Ye, Shiwei Huang, Hao Chen, Rui Zhou, Wenbing Jiang
Article Number: 119
Published online on: 03 December 2020

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Article Open Access

A novel danshensu/tetramethypyrazine derivative attenuates oxidative stress‑induced autophagy injury via the AMPK‑mTOR‑Ulk1 signaling pathway in cardiomyocytes

Caipeng Xie, Jingxiong Luo, Huihui Hu, Liang Wang, Pei Yu, Lipeng Xu, Yewei Sun, Yuqiang Wang, Luchen Shan
Article Number: 118
Published online on: 03 December 2020

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Article Open Access

Notch3 and its CADASIL mutants differentially regulate cellular phenotypes

Chunjing Lin, Ziyang Huang, Riyong Zhou, Ying Zhou, Yangping Shentu, Kang Yu, Yu Zhang
Article Number: 117
Published online on: 03 December 2020

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Article Open Access

MicroRNA‑451a prevents cutaneous squamous cell carcinoma progression via the 3‑phosphoinositide‑dependent protein kinase‑1‑mediated PI3K/AKT signaling pathway Retraction in /10.3892/etm.2024.12568

Jixing Fu, Jianhua Zhao, Huamin Zhang, Xiaoli Fan, Wenjun Geng, Shaohua Qiao
Article Number: 116
Published online on: 03 December 2020

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Review Open Access

Clinical characteristics and infectivity of asymptomatic carriers of SARS‑CoV‑2 (Review)

Wanying Zhang, Xuejie Wu, Hui Zhou, Feng Xu
Article Number: 115
Published online on: 03 December 2020

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Article Open Access

Regulation of dimethylarginine dimethylaminohydrolase 2 expression by NF‑κB acetylation

Jiaqi Li, Lu Sun, Yinghui Li
Article Number: 114
Published online on: 03 December 2020

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Review Open Access

The role of dentists in controlling hepatocellular carcinoma in Japan (Review)

Yumiko Nagao
Article Number: 113
Published online on: 03 December 2020

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Article Open Access

Increased expression of IFN‑γ in preeclampsia impairs human trophoblast invasion via a SOCS1/JAK/STAT1 feedback loop

Huiqiang Liu, Wenhao Wang, Chongdong Liu
Article Number: 112
Published online on: 02 December 2020

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Dexmedetomidine protects against endothelial injury in septic rats induced by cecal ligation and puncture by decreasing angiopoietin 2 and increasing vascular endothelial cadherin levels

Peng Zhang, Ji Peng, Yun-Qin Ren, Han Zheng, Hong Yan
Article Number: 111
Published online on: 02 December 2020

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Different mutations at position 562 of the hepatitis E virus capsid proteins exhibit differential effects on viral neutralizing activity

Mingjie Xu, Lizhi Sun, Yan Wang, Shuchun Gao, Weihua Yang, Meng Li
Article Number: 110
Published online on: 27 November 2020

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miR‑335‑5P contributes to human osteoarthritis by targeting HBP1

Xiaokun Lu, Yu Li, Huimin Chen, Yuancheng Pan, Ran Lin, Shunyou Chen
Article Number: 109
Published online on: 27 November 2020

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Production of a SCID mouse model of medulloblastoma to explore the therapeutic value of targeting tumor driver genes

Yong Han, Min Chen, Hangzhou Wang
Article Number: 108
Published online on: 27 November 2020

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Eugenol protects cells against oxidative stress via Nrf2

Leina Ma, Jia Liu, Qian Lin, Yuchao Gu, Wengong Yu
Article Number: 107
Published online on: 27 November 2020

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Article

miR‑218 inhibits glucose metabolism in non‑small cell lung cancer via the NF‑κB signaling pathway

Wenxian Tian, Xiangfei Yuan, Yongna Song, Jianxia Zhai, Haixia Wei, Linna Wang, Dan Li, Qiusheng Chen
Article Number: 106
Published online on: 27 November 2020

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Article

Dietary vitamin intake and risk of metabolic syndrome among centenarians in China

Zhiqing Peng, Yanyan Wang, Xianyong Huang, Qiao Zhu, Yali Zhao, Hengge Xie, Jianjun Wu
Article Number: 105
Published online on: 27 November 2020

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Variants of CAPN3 cause limb‑girdle muscular dystrophy type 2A in two Chinese families

Jie Zheng, Xiaowei Xu, Xinjie Zhang, Xuetao Wang, Jianbo Shu, Chunquan Cai
Article Number: 104
Published online on: 27 November 2020

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IFN‑γ and IL‑18 in conditioned media of parasite‑infected host and IL‑21‑silenced colorectal cancer cells

Peng Ge, Ching Yi Ong, Abdalla Eshtiyag Abdalkareem, Boon Yin Khoo, Bo Yuan
Article Number: 103
Published online on: 27 November 2020

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Journal Cover
March-2026 Volume 31 Issue 3

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Impact Factor: 2.3

Article Open Access

Effect of SGLT2 inhibitors on heart failure outcomes in patients with and without diabetes: A systematic review and meta‑analysis of randomized controlled trials

Duaa Abdullah Bafail, Noura Hamdi Alhalees
Article Number: 84
Published online on: 28 January 2026

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Exploring the protective mechanisms and therapeutic potential of carnosic acid against acute respiratory distress syndrome through molecular docking, molecular dynamics and experimental verification

Quan Li, Lili Ding, Haijun Sun, Weichao Ding, Mengmeng Wang, Zhaorui Sun, Congxue Ma
Article Number: 83
Published online on: 28 January 2026

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Review

Exploring the roots of schizophrenia: Current research and future directions (Review)

Shuang Lv, Chunxia Luo
Article Number: 82
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] miR‑146a‑5p protects against renal injury in MRL/lpr mice via improvement of the Treg/Th17 imbalance by targeting the TRAF6/NF‑κB axis

Jiajia Teng, Feng Yang, Xiaoling Li
Article Number: 81
Published online on: 28 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑24‑3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl‑2‑like protein 11

Huanxin Zhang, Shizhen Xue, Yi Feng, Jun Shen, Jixian Zhao
Article Number: 80
Published online on: 26 January 2026

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Efficacy and safety of unilateral biportal endoscopy vs. percutaneous endoscopic interlaminar approach in lumbar disc herniation: A meta‑analysis​

Yuhao Gao, Fangzheng He, Ji Wen, Shilei Qin, Pengfei Han, Yunfeng Xu
Article Number: 79
Published online on: 23 January 2026

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Case Report Open Access

Intralobar pulmonary sequestration coexisting with pulmonary cryptococcosis: A case report and literature review

Dan Cheng, Yue Wang, Jun Li, Dan Yu, Yunyun Wang, Jinbo Fan, Jiankun Wang, Liqun He
Article Number: 78
Published online on: 23 January 2026

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Tumor‑associated macrophages suppress estrogen receptor‑β expression in triple‑negative breast cancer through the PI3K/AKT pathway

Qiulei Zhang, Di Guo, Gaoran Xu, Rong Xie, Yuqing Deng, Peng Fu, Jinnan Wan
Article Number: 77
Published online on: 21 January 2026

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Development of a diagnostic model for esophageal achalasia assessed by esophageal high‑resolution manometry using artificial intelligence

Maiko Tabuchi, Yasuhiko Nakao, Hitomi Minami, Hiroko Inomata, Junya Shiota, Taro Akashi, Keiichi Hashiguchi, Moto Kitayama, Kayoko Matsushima, Naoyuki Yamaguchi, Yuko Akazawa, Hisamitsu Miyaaki
Article Number: 76
Published online on: 21 January 2026

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Case Report

Use of metagenomic next‑generation sequencing to diagnose Tropheryma whipplei infection‑related pneumonia: A case report

Yutu Luo, Haibing Ding, Jiahua Pan, Guangyang Xu
Article Number: 75
Published online on: 21 January 2026

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Effect of rivaroxaban on DNA damage in an ischemia-reperfusion model: Evaluation of 8‑OHdG levels

Ceren Sayarer, Abidin Cenk Erdal, Tuğra Gençpinar, Özlem Gürsoy Doruk, Tuncay Küme
Article Number: 74
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Hepatoprotective activity of chrysin is mediated through TNF‑α in chemically‑induced acute liver damage: An in vivo study and molecular modeling 

Anca Hermenean, Teodora Mariasiu, Inmaculada Navarro-González, Josefina Vegara-Meseguer, Eftimie Miuțescu, Sandipan Chakraborty, Horacio Pérez-Sánchez
Article Number: 73
Published online on: 21 January 2026

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Retraction Open Access

[Retracted] Gambogic acid suppresses colon cancer cell activity in vitro

Zailong Zhou, Jian Ma
Article Number: 72
Published online on: 19 January 2026

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Case Report

Identification of a novel KISS1R (GPR54) gene variant (c.505+2T>G) in a patient with congenital hypogonadotropic hypogonadism: A case report and literature review

Burak Menekse, Enes Ucgul, Abdullatif Bakir, Sema Hepsen, Ilknur Ozturk Unsal, Muhammed Kizilgul, Takako Araki, Erman Cakal
Article Number: 71
Published online on: 16 January 2026

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Postoperative hypofractionated intensity-modulated proton therapy to control recurrent paraganglioma at the jugular foramen: A case report and literature review

Wei Wang, Yingxia Yuan, Jiwei Bai, Yue Zou, Dongxue Zhou, Jun Zhao, Shuyan Zhang, Zishen Wang, Jie Wang, Jingjing Kong, Lu Yang, Masashi Mizumoto, Hideyuki Sakurai, Shosei Shimizu
Article Number: 70
Published online on: 16 January 2026

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Article

Serum antithrombin III level predicts acute kidney injury in patients with traumatic brain injury

Ruoran Wang, Min He, Jianguo Xu
Article Number: 69
Published online on: 16 January 2026

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Retraction Open Access

[Retracted] β‑asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal‑regulated kinase signaling pathway

Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong Li
Article Number: 68
Published online on: 12 January 2026

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Case Report Open Access

Rare co‑occurrence of gastrointestinal stromal tumors and leiomyomas: A case report and review of the literature

Yu Zhang, Xiaoqiong Shi, Wenfu Xie, Meilin He, Shan Zhang, Xue Peng, Hao Lei, Xulei Li, Haiying Liu, Qiao Shu, Fangyuan Zou, Mingyong Wei
Article Number: 67
Published online on: 09 January 2026

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No increased risk of hepatic enzyme abnormalities with non‑peptidic thrombopoietin receptor agonists in immune thrombocytopenia: A meta‑analysis of randomized controlled trials

Nan Shen, Rang Wu, Tiantian Lu, Song Liu, Yazhou Jiang, Jingjing Yan, Tao Ning, Chang Dong, Jianqin Li, Suyue Zhu
Article Number: 66
Published online on: 09 January 2026

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Case Report

Submucosal colonic fecalith mimicking a submucosal malignant tumor at the anastomotic site after colon cancer: A case report

Motoaki Yuhi, Masatsugu Hiraki, Shin Takesue, Mariko Hashiguchi, Megumi Nishiyama, Yoshiaki Egashira, Tatsuya Manabe, Hirokazu Noshiro
Article Number: 65
Published online on: 08 January 2026

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Article

Clinical characteristics of acute primary angle closure following COVID‑19 during the Omicron outbreak in China

Jianhui Zhang, Yingying Xue, Liu Zhang, Yuhong Wang, Shancheng Si
Article Number: 64
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Aberrant expression and mechanism of miR‑130b‑3p/phosphatase and tensin homolog in nephroblastoma in children

Yifeng Hu, Jingtie Yan
Article Number: 63
Published online on: 05 January 2026

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Case Report Open Access

Novel variants in STAG2 and PKD1 associate with multiple congenital malformations and autosomal dominant polycystic kidney disease in a Chinese family: A case report and literature review

Qi Yang, Qiang Zhang, Sheng Yi, Xunzhao Zhou, Yiyan Ruan, Shujie Zhang, Shang Yi, Qinle Zhang, Zailng Qin, Jingsi Luo
Article Number: 62
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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