Primary, secondary or less frequent causes of immune thrombocytopenia: A case report

  • Authors:
    • Minodora Onisâi
    • Ana-Maria Vlădăreanu
    • Iuliana Iordan
    • Horia Bumbea
    • Mihaela Găman
    • Cristina Ciufu
    • Irina Voican
    • Diana Cîșleanu
    • Daniela Vasile
    • Cristina Marinescu
    • Anca Nicolescu
    • Andreea Spînu
    • Raluca Nistor
    • Adrian Alexandru
  • View Affiliations

  • Published online on: August 2, 2021     https://doi.org/10.3892/etm.2021.10530
  • Article Number: 1096
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Abstract

Primary immune thrombocytopenia (ITP) is characterized by isolated low platelet count and it is a diagnosis of exclusion, contrasting to secondary ITP. Therefore, a positive diagnosis is difficult and requires extensive investigation. Some of the underlying conditions that are associated with ITP are lymphoproliferative disorders and infections, especially viral ones. In the present study, the case of a patient diagnosed with diffuse large B‑cell lymphoma, who received chemotherapy and autologous hematopoietic stem cell transplantation is presented. After a complete remission of four years, the patient presented with sudden intense hemorrhagic syndrome and severely decreased platelet count. The most frequent causes of secondary ITP were excluded, including lymphoma relapse, and intravenous corticosteroids were started. However, shortly after hospital admission, the patient developed neuro‑psychiatric anomalies, fever and pancytopenia, and West‑Nile encephalitis was diagnosed. Although the initial development was favorable, he started to complain of progressive severe muscle weakness and eventually succumbed to infectious complications in the setting of prolonged hospitalization, corticotherapy, and immobilization.
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October-2021
Volume 22 Issue 4

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Onisâi M, Vlădăreanu A, Iordan I, Bumbea H, Găman M, Ciufu C, Voican I, Cîșleanu D, Vasile D, Marinescu C, Marinescu C, et al: Primary, secondary or less frequent causes of immune thrombocytopenia: A case report. Exp Ther Med 22: 1096, 2021.
APA
Onisâi, M., Vlădăreanu, A., Iordan, I., Bumbea, H., Găman, M., Ciufu, C. ... Alexandru, A. (2021). Primary, secondary or less frequent causes of immune thrombocytopenia: A case report. Experimental and Therapeutic Medicine, 22, 1096. https://doi.org/10.3892/etm.2021.10530
MLA
Onisâi, M., Vlădăreanu, A., Iordan, I., Bumbea, H., Găman, M., Ciufu, C., Voican, I., Cîșleanu, D., Vasile, D., Marinescu, C., Nicolescu, A., Spînu, A., Nistor, R., Alexandru, A."Primary, secondary or less frequent causes of immune thrombocytopenia: A case report". Experimental and Therapeutic Medicine 22.4 (2021): 1096.
Chicago
Onisâi, M., Vlădăreanu, A., Iordan, I., Bumbea, H., Găman, M., Ciufu, C., Voican, I., Cîșleanu, D., Vasile, D., Marinescu, C., Nicolescu, A., Spînu, A., Nistor, R., Alexandru, A."Primary, secondary or less frequent causes of immune thrombocytopenia: A case report". Experimental and Therapeutic Medicine 22, no. 4 (2021): 1096. https://doi.org/10.3892/etm.2021.10530