|
1
|
Rizzato C, Campa D, Talar-Wojnarowska R,
Halloran C, Kupcinskas J, Butturini G, Mohelníková-Duchoňová B,
Sperti C, Tjaden C, Ghaneh P, et al: Association of genetic
polymorphisms with survival of pancreatic ductal adenocarcinoma
patients. Carcinogenesis. 37:957–964. 2016.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Vincent A, Herman J, Schulick R, Hruban RH
and Goggins M: Pancreatic cancer. Lancet. 378:607–620.
2011.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Rahib L, Smith BD, Aizenberg R, Rosenzweig
AB, Fleshman JM and Matrisian LM: Projecting cancer incidence and
deaths to 2030: The unexpected burden of thyroid, liver, and
pancreas cancers in the United States. Cancer Res. 74:2913–2921.
2014.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Halbrook CJ and Lyssiotis CA: Employing
metabolism to improve the diagnosis and treatment of pancreatic
cancer. Cancer Cell. 31:5–19. 2017.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Griffin JF, Poruk KE and Wolfgang CL:
Pancreatic cancer surgery: Past, present, and future. Chin J Cancer
Res. 27:332–348. 2015.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Maitra A, Kern SE and Hruban RH: Molecular
pathogenesis of pancreatic cancer. Best Pract Res Clin
Gastroenterol. 20:211–226. 2006.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Long J, Liu Z, Wu X, Xu Y and Ge C: Gene
expression profile analysis of pancreatic cancer based on
microarray data. Mol Med Rep. 13:3913–3919. 2016.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Morris JP IV, Wang SC and Hebrok M: KRAS,
hedgehog, wnt and the twisted developmental biology of pancreatic
ductal adenocarcinoma. Nat Rev Cancer. 10:683–695. 2010.PubMed/NCBI View
Article : Google Scholar
|
|
9
|
Lauth M and Toftgård R: Hedgehog signaling
and pancreatic tumor development. Adv Cancer Res. 110:1–17.
2011.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Shigeyasu K, Toden S, Zumwalt TJ, Okugawa
Y and Goel A: Emerging role of MicroRNAs as liquid biopsy
biomarkers in gastrointestinal cancers. Clin Cancer Res.
23:2391–2399. 2017.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Cui Z, Liu G and Kong D: miRNA27a promotes
the proliferation and inhibits apoptosis of human pancreatic cancer
cells by wnt/β-catenin pathway. Oncol Rep. 39:755–763.
2018.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Zhao DW, Hou YS, Sun FB, Han B and Li SJ:
Effects of miR-132 on proliferation and apoptosis of pancreatic
cancer cells via hedgehog signaling pathway. Eur Rev Med Pharmacol
Sci. 23:1978–1985. 2019.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Barrett T, Wilhite SE, Ledoux P,
Evangelista C, Kim IF, Tomashevsky M, Marshall KA, Phillippy KH,
Sherman PM, Holko M, et al: NCBI GEO: Archive for functional
genomics data sets-update. Nucleic Acids Res. 41:D991–D995.
2013.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Clough E and Barrett T: The gene
expression omnibus database. Methods Mol Biol. 1418:93–110.
2016.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Zhang G, Schetter A, He P, Funamizu N,
Gaedcke J, Ghadimi BM, Ried T, Hassan R, Yfantis HG, Lee DH, et al:
DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity
and predicts clinical outcome in pancreatic ductal adenocarcinoma.
PLoS One. 7(e31507)2012.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Pei H, Li L, Fridley BL, Jenkins GD,
Kalari KR, Lingle W, Petersen G, Lou Z and Wang L: FKBP51 affects
cancer cell response to chemotherapy by negatively regulating Akt.
Cancer Cell. 16:259–266. 2009.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Badea L, Herlea V, Dima SO, Dumitrascu T
and Popescu I: Combined gene expression analysis of whole-tissue
and microdissected pancreatic ductal adenocarcinoma identifies
genes specifically overexpressed in tumor epithelia.
Hepatogastroenterology. 55:2016–2027. 2008.PubMed/NCBI
|
|
18
|
Yu G, Wang LG, Han Y and He QY:
clusterProfiler: An R package for comparing biological themes among
gene clusters. OMICS. 16:284–287. 2012.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Szklarczyk D, Franceschini A, Wyder S,
Forslund K, Heller D, Huerta-Cepas J, Simonovic M, Roth A, Santos
A, Tsafou KP, et al: STRING v10: Protein-protein interaction
networks, integrated over the tree of life. Nucleic Acids Res.
43:D447–D452. 2015.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Gene Ontology Consortium. The gene
ontology (GO) project in 2006. Nucleic Acids Res. 34:D322–D326.
2006.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Ashburner M, Ball CA, Blake JA, Botstein
D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT,
et al: Gene ontology: Tool for the unification of biology. The gene
ontology consortium. Nat Genet. 25:25–29. 2000.PubMed/NCBI View
Article : Google Scholar
|
|
22
|
Tang Z, Li C, Kang B, Gao G, Li C and
Zhang Z: GEPIA: A web server for cancer and normal gene expression
profiling and interactive analyses. Nucleic Acids Res. 45:W98–W102.
2017.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T) method. Methods. 25:402–408.
2001.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Krishan A: Rapid flow cytofluorometric
analysis of mammalian cell cycle by propidium iodide staining. J
Cell Biol. 66:188–193. 1975.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Ilic M and Ilic I: Epidemiology of
pancreatic cancer. World J Gastroenterology. 22:9694–9705.
2016.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Miller KD, Siegel RL, Lin CC, Mariotto AB,
Kramer JL, Rowland JH, Stein KD, Alteri R and Jemal A: Cancer
treatment and survivorship statistics, 2016. CA Cancer J Clin.
66:271–289. 2016.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Courtney KD, Corcoran RB and Engelman JA:
The PI3K pathway as drug target in human cancer. J Clin Oncol.
28:1075–1083. 2010.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Ebrahimi S, Hosseini M, Shahidsales S,
Maftouh M, Ferns GA, Ghayour-Mobarhan M, Hassanian SM and Avan A:
Targeting the Akt/PI3K signaling pathway as a potential therapeutic
strategy for the treatment of pancreatic cancer. Curr Med Chem.
24:1321–1331. 2017.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Hu D, Ansari D, Zhou Q, Sasor A,
Hilmersson KS and Andersson R: Stromal fibronectin expression in
patients with resected pancreatic ductal adenocarcinoma. World J
Surg Oncol. 17(29)2019.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Liu JX, Li A, Zhou LY, Liu XF, Wei ZH,
Wang XZ and Ying HQ: Significance of combined preoperative serum
Alb and dNLR for diagnosis of pancreatic cancer. Future Oncol.
14:229–239. 2018.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Liu Z, Jin K, Guo M, Long J, Liu L, Liu C,
Xu J, Ni Q, Luo G and Yu X: Prognostic value of the CRP/Alb ratio,
a novel inflammation-based score in pancreatic cancer. Ann Surg
Oncol. 24:561–568. 2017.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Hao C, Li Z, Zhang X, Zhang H, Shang H,
Bao J and Wang H: Expression and clinical significance of EGF and
TGF-alpha in chronic pancreatitis and pancreatic cancer. Minerva
Endocrinol. 43:253–258. 2018.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Cole WG: Collagen genes: Mutations
affecting collagen structure and expression. Prog Nucleic Acid Res
Mol Biol. 47:29–80. 1994.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Exposito JY, Valcourt U, Cluzel C and
Lethias C: The fibrillar collagen family. Int J Mol Sci.
11:407–426. 2010.PubMed/NCBI View Article : Google Scholar
|
|
35
|
de Caceres II, Dulaimi E, Hoffman AM,
Al-Saleem T, Uzzo RG and Cairns P: Identification of novel target
genes by an epigenetic reactivation screen of renal cancer. Cancer
Res. 66:5021–5028. 2006.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Hayashi M, Nomoto S, Hishida M, Inokawa Y,
Kanda M, Okamura Y, Nishikawa Y, Tanaka C, Kobayashi D, Yamada S,
et al: Identification of the collagen type 1 α 1 gene (COL1A1) as a
candidate survival-related factor associated with hepatocellular
carcinoma. BMC Cancer. 14(108)2014.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Bonazzi VF, Nancarrow DJ, Stark MS, Moser
RJ, Boyle GM, Aoude LG, Schmidt C and Hayward NK: Cross-platform
array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as
genes frequently silenced by methylation in melanoma. PLoS One.
6(e26121)2011.PubMed/NCBI View Article : Google Scholar
|
|
38
|
Li J, Ding Y and Li A: Identification of
COL1A1 and COL1A2 as candidate prognostic factors in gastric
cancer. World J Surg Oncol. 14(297)2016.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Ikenaga N, Ohuchida K, Mizumoto K, Akagawa
S, Fujiwara K, Eguchi D, Kozono S, Ohtsuka T, Takahata S and Tanaka
M: Pancreatic cancer cells enhance the ability of collagen
internalization during epithelial-mesenchymal transition. PLoS One.
7(e40434)2012.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Chakravarthy D, Muñoz AR, Su A, Hwang RF,
Keppler BR, Chan DE, Halff G, Ghosh R and Kumar AP: Palmatine
suppresses glutamine-mediated interaction between pancreatic cancer
and stellate cells through simultaneous inhibition of survivin and
COL1A1. Cancer Lett. 419:103–115. 2018.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Gong J, Lu X, Xu J, Xiong W, Zhang H and
Yu X: Coexpression of UCA1 and ITGA2 in pancreatic cancer cells
target the expression of miR-107 through focal adhesion pathway. J
Cell Physiol. 234:12884–12896. 2018.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Chen P, Wan D, Zheng D, Zheng Q, Wu F and
Zhi Q: Long non-coding RNA UCA1 promotes the tumorigenesis in
pancreatic cancer. Biomed Pharmacother. 83:1220–1226.
2016.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Jing C, Ma G, Li X, Wu X, Huang F, Liu K
and Liu Z: MicroRNA-17/20a impedes migration and invasion via
TGF-β/ITGB6 pathway in esophageal squamous cell carcinoma. Am J
Cancer Res. 6:1549–1562. 2016.PubMed/NCBI
|
|
44
|
Wu M, Li X, Zhang T, Liu Z and Zhao Y:
Identification of a nine-gene signature and establishment of a
prognostic nomogram predicting overall survival of pancreatic
cancer. Front Oncol. 9(996)2019.PubMed/NCBI View Article : Google Scholar
|
|
45
|
Zhou Y, Chen Y, Ding W, Hua Z, Wang L, Zhu
Y, Qian H and Dai T: LncRNA UCA1 impacts cell proliferation,
invasion, and migration of pancreatic cancer through regulating
miR-96/FOXO3. IUBMB life. 70:276–290. 2018.PubMed/NCBI View Article : Google Scholar
|
