The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke

  • Authors:
    • Nicolae Ovidiu Pop
    • Delia Mirela Tit
    • Camelia Cristina Diaconu
    • Mihai Alexandru Munteanu
    • Emilia Elena Babes
    • Manuela Stoicescu
    • Mircea Ioachim Popescu
    • Simona Bungau
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  • Published online on: September 27, 2021     https://doi.org/10.3892/etm.2021.10805
  • Article Number: 1371
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Abstract

Stroke is one of the leading causes of mortality globally and a main cause of disability. The objective of this study was to evaluate the importance and utility of the Alberta Stroke Program Early CT Score (ASPECTS) as a mortality predictor factor in diabetic vs. non‑diabetic patients with acute ischemic stroke (AIS), correlated with age, monocyte values, and high‑sensitivity cardiac troponin I (hs‑cTnI). The prospective longitudinal observational study included 340 patients with AIS divided into two groups: diabetics and non‑diabetics. ASPECTS was evaluated within the first 24 h after admission to the center. The ASPECTS was lower in the group of diabetic patients on average 4.9 vs. 6.05 (P<0.0001). As the age of the patients increased, the lower the ASPECTS and the higher infarct size, indicating a statistically significant (P<0.0001) result. The optimal correlation was observed between infarct size (ASPECTS) and hs‑cTnI serum level [95% confidence interval (CI): ‑0.3216 to ‑0.1193; P<0.0001]. Almost 94% of patients who had an ASPECTS higher than 3 points on admission survived, resulting in a favorable outcome and a very good predictability of the score (95% CI: 0.85 to 0.926, P<0.0001). The ASPECTS is a mortality predictor, its value correlating inversely with the severity and evolution of patients, confirming a good predictability with good specificity, sensitivity and area under the curve.
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December-2021
Volume 22 Issue 6

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Pop NO, Tit DM, Diaconu CC, Munteanu MA, Babes EE, Stoicescu M, Popescu MI and Bungau S: The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke. Exp Ther Med 22: 1371, 2021
APA
Pop, N.O., Tit, D.M., Diaconu, C.C., Munteanu, M.A., Babes, E.E., Stoicescu, M. ... Bungau, S. (2021). The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke. Experimental and Therapeutic Medicine, 22, 1371. https://doi.org/10.3892/etm.2021.10805
MLA
Pop, N. O., Tit, D. M., Diaconu, C. C., Munteanu, M. A., Babes, E. E., Stoicescu, M., Popescu, M. I., Bungau, S."The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke". Experimental and Therapeutic Medicine 22.6 (2021): 1371.
Chicago
Pop, N. O., Tit, D. M., Diaconu, C. C., Munteanu, M. A., Babes, E. E., Stoicescu, M., Popescu, M. I., Bungau, S."The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1371. https://doi.org/10.3892/etm.2021.10805