Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Experimental and Therapeutic Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-0981 Online ISSN: 1792-1015
Journal Cover
December-2021 Volume 22 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2021 Volume 22 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5

  • Authors:
    • Jinye Lu
    • Beibei Gu
    • Wei Lu
    • Jing Liu
    • Jiang Lu
  • View Affiliations / Copyright

    Affiliations: Laboratory of Animal Immunonutrition, Jiangsu Agri‑animal Husbandry Vocational College, Taizhou, Jiangsu 225300, P.R. China
    Copyright: © Lu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 1425
    |
    Published online on: October 11, 2021
       https://doi.org/10.3892/etm.2021.10860
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Bovine mastitis is a threat to the health of the dairy cow. MicroRNAs (miRs) serve an important role in the progression of bovine mastitis, regulating immune and defense responses. The present study aimed to investigate the possible effects and mechanisms of bovine mastitis underlying miR‑142‑5p and Bcl‑2 associated athanogene 5 (BAG5) in in vitro lipopolysaccharide (LPS)‑induced models. Reverse transcription‑quantitative PCR and western blotting were performed to determine mRNA and protein expression levels, respectively. ELISAs were conducted to assess the levels of cytokines and an immunofluorescence assay was performed to determine the expression of BAG5. Cell Counting Kit‑8, clone formation and 5‑ethynyl‑2'‑deoxyuridine assays were conducted to determine cell viability and proliferation of bovine mammary epithelial MAC‑T cells, respectively. Flow cytometry was performed to measure MAC‑T cell cycle distribution and apoptosis, and a luciferase assay was conducted to verify whether BAG5 was a target of miR‑142‑5p. The results indicated that miR‑142‑5p was upregulated in MAC‑T cells treated with LPS compared with the control group. miR‑142‑5p mimics transfection significantly activated the cytokines TNF‑α, IL‑1β, IL‑6 and IL‑8, and significantly increased the expression levels of NF‑κB signaling pathway‑related proteins in LPS‑treated cells. The luciferase activity of MAC‑T cells treated with miR‑142‑5p mimics and BAG5 3'untranslated region wild type decreased, compared with mutant type. By contrast, BAG5 overexpression significantly downregulated the levels of cytokines, including TNF‑α, IL‑1β, IL‑6 and IL‑8, in LPS‑treated cells. BAG5 overexpression significantly promoted cell proliferation and viability, decreased apoptosis, and regulated Caspase‑3, Caspase‑9, Bcl‑2 and Bax expression in LPS‑treated MAC‑T cells, which was significantly reversed by transfection with miR‑142‑5p mimics. In conclusion, the results of the present study suggested that miR‑142‑5p may promote the progression of bovine mastitis via targeting BAG5. Therefore, the present study provided the foundations for future investigations.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

View References

1 

Cheng WN, Jeong CH, Seo HG and Han SG: Moringa extract attenuates inflammatory responses and increases gene expression of casein in bovine mammary epithelial cells. Animals (Basel). 9(391)2019.PubMed/NCBI View Article : Google Scholar

2 

Fazel F, Jamshidi A and Khoramian B: Phenotypic and genotypic study on antimicrobial resistance patterns of E. coli isolates from bovine mastitis. Microb Pathog. 132:355–361. 2019.PubMed/NCBI View Article : Google Scholar

3 

Locatelli C, Barberio A, Bonamico S, Casula A, Moroni P and Bronzo V: Identification of multidrug-resistant escherichia coli from bovine clinical mastitis using a ceftiofur-supplemented medium. Foodborne Pathog Dis. 16:590–596. 2019.PubMed/NCBI View Article : Google Scholar

4 

Shen P, Zhang Z, Zhu K, Cao H, Liu J, Lu X, Li Y, Jing Y, Yuan X, Fu Y, et al: Evodiamine prevents dextran sulfate sodium-induced murine experimental colitis via the regulation of NF-κB and NLRP3 inflammasome. Biomed Pharmacother. 110:786–795. 2019.PubMed/NCBI View Article : Google Scholar

5 

Zhang X, Zhao Y, Bai D, Yuan X and Cong S: Schizandrin protects H9c2 cells against lipopolysaccharide-induced injury by downregulating Smad3. J Biochem Mol Toxicol. 33(e22301)2019.PubMed/NCBI View Article : Google Scholar

6 

Bielaszewska M, Marejková M, Bauwens A, Kunsmann-Prokscha L, Mellmann A and Karch H: Enterohemorrhagic Escherichia coli O157 outer membrane vesicles induce interleukin 8 production in human intestinal epithelial cells by signaling via Toll-like receptors TLR4 and TLR5 and activation of the nuclear factor NF-κB. Int J Med Microbiol. 308:882–889. 2018.PubMed/NCBI View Article : Google Scholar

7 

Gonen E, Nedvetzki S, Naor D and Shpigel NY: CD44 is highly expressed on milk neutrophils in bovine mastitis and plays a role in their adhesion to matrix and mammary epithelium. Vet Res. 39(29)2008.PubMed/NCBI View Article : Google Scholar

8 

Enger BD, Tucker HLM, Nickerson SC, Parsons CLM and Akers RM: Effects of Staphylococcus aureus intramammary infection on the expression of estrogen receptor α and progesterone receptor in mammary glands of nonlactating cows administered estradiol and progesterone to stimulate mammary growth. J Dairy Sci. 102:2607–2617. 2019.PubMed/NCBI View Article : Google Scholar

9 

Naveed A, Ur-Rahman S, Abdullah S and Naveed MA: A concise review of microRNA exploring the insights of microRNA regulations in bacterial, viral and metabolic diseases. Mol Biotechnol. 59:518–529. 2017.PubMed/NCBI View Article : Google Scholar

10 

Chen X, Tan W, Li W, Li W, Zhu S, Zhong J, Shang C and Chen Y: miR-1226-3p promotes sorafenib sensitivity of hepatocellular carcinoma via downregulation of DUSP4 expression. J Cancer. 10:2745–2753. 2019.PubMed/NCBI View Article : Google Scholar

11 

Lai YC, Fujikawa T, Maemura T, Ando T, Kitahara G, Endo Y, Yamato O, Koiwa M, Kubota C and Miura N: Inflammation-related microRNA expression level in the bovine milk is affected by mastitis. PLoS One. 12(e0177182)2017.PubMed/NCBI View Article : Google Scholar

12 

Chen Z, Xu X, Tan T, Chen D, Liang H, Sun K, Li M, Zhang H, Mao Y and Yang Z: MicroRNA-145 regulates immune cytokines via targeting FSCN1 in Staphylococcus aureus-induced mastitis in dairy cows. Reprod Domest Anim. 54:882–891. 2019.PubMed/NCBI View Article : Google Scholar

13 

Wang XP, Luoreng ZM, Zan LS, Li F and Li N: Bovine miR-146a regulates inflammatory cytokines of bovine mammary epithelial cells via targeting the TRAF6 gene. J Dairy Sci. 100:7648–7658. 2017.PubMed/NCBI View Article : Google Scholar

14 

Lai YC, Fujikawa T, Ando T, Kitahara G, Koiwa M, Kubota C and Miura N: Rapid communication: MiR-92a as a housekeeping gene for analysis of bovine mastitis-related microRNA in milk. J Anim Sci. 95:2732–2735. 2017.PubMed/NCBI View Article : Google Scholar

15 

Sun J, Aswath K, Schroeder SG, Lippolis JD, Reinhardt TA and Sonstegard TS: MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection. BMC Genomics. 16(806)2015.PubMed/NCBI View Article : Google Scholar

16 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T) method. Methods. 25:402–408. 2001.PubMed/NCBI View Article : Google Scholar

17 

Sun L, Chen L, Wang F, Zheng X, Yuan C, Niu Q, Li Z, Deng L, Zheng B, Li C and Zhou X: Exogenous hydrogen sulfide prevents lipopolysaccharide-induced inflammation by blocking the TLR4/NF-κB pathway in MAC-T cells. Gene. 710:114–121. 2019.PubMed/NCBI View Article : Google Scholar

18 

Wang W, Hu X, Shen P, Zhang N and Fu Y: Sodium houttuyfonate inhibits LPS-induced inflammatory response via suppressing TLR4/NF-ĸB signaling pathway in bovine mammary epithelial cells. Microb Pathog. 107:12–16. 2017.PubMed/NCBI View Article : Google Scholar

19 

Chen H, Lan Z, Li Q and Li Y: Abnormal expression of long noncoding RNA FGD5-AS1 affects the development of periodontitis through regulating miR-142-3p/SOCS6/NF-κB pathway. Artif Cells Nanomed Biotechnol. 47:2098–2106. 2019.PubMed/NCBI View Article : Google Scholar

20 

Park J, Jeong S, Park K, Yang K and Shin S: Expression profile of microRNAs following bone marrow-derived mesenchymal stem cell treatment in lipopolysaccharide-induced acute lung injury. Exp Ther Med. 15:5495–5502. 2018.PubMed/NCBI View Article : Google Scholar

21 

Liu X, Hong C, Wu S, Song S, Yang Z, Cao L, Song T and Yang Y: Downregulation of lncRNA TUG1 contributes to the development of sepsis-associated acute kidney injury via regulating miR-142-3p/sirtuin 1 axis and modulating NF-κB pathway. J Cell Biochem: Mar 4, 2019 (Epub ahead of print).

22 

Ohashi E, Kohno K, Arai N, Harashima A, Ariyasu T and Ushio S: Adenosine N1-oxide exerts anti-inflammatory effects through the PI3K/Akt/GSK-3β signaling pathway and promotes osteogenic and adipocyte differentiation. Biol Pharm Bull. 42:968–976. 2019.PubMed/NCBI View Article : Google Scholar

23 

Chen Q, Zhang KX, Li TY, Piao XM, Lian ML, An RB and Jiang J: Cardamine komarovii flower extract reduces lipopolysaccharide-induced acute lung injury by inhibiting MyD88/TRIF signaling pathways. Chin J Nat Med. 17:461–468. 2019.PubMed/NCBI View Article : Google Scholar

24 

Han FL, Liang F, Jiang TC and Liu M: Increased expression of CXCR5 and CXCL13 in mice with experimental autoimmune myocarditis. Eur Rev Med Pharmacol Sci. 21:1860–1867. 2017.PubMed/NCBI

25 

Su S, Zhao Q, He C, Huang D, Liu J, Chen F, Chen J, Liao JY, Cui X, Zeng Y, et al: miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commu. 6(8523)2015.PubMed/NCBI View Article : Google Scholar

26 

Lou Z, Peng Z, Wang B, Li X, Li X and Zhang X: miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway. J Bone Miner Metab. 37:815–824. 2019.PubMed/NCBI View Article : Google Scholar

27 

Liu Y, Chen W, Ali T, Alkasir R, Yin J, Liu G and Han B: Staphylococcal enterotoxin H induced apoptosis of bovine mammary epithelial cells in vitro. Toxins (Basel). 6:3552–3567. 2014.PubMed/NCBI View Article : Google Scholar

28 

Liu S, Xiao Z, Ai F, Liu F, Chen X, Cao K, Ren W, Zhang X, Shu P and Zhang D: miR-142-5p promotes development of colorectal cancer through targeting SDHB and facilitating generation of aerobic glycolysis. Biomed Pharmacother. 92:1119–1127. 2017.PubMed/NCBI View Article : Google Scholar

29 

Kim JA, Kim Y, Kwon BM and Han DC: The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and Bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters. J Biol Chem. 288:28713–28726. 2013.PubMed/NCBI View Article : Google Scholar

30 

Li C, Jiang JY, Wang JM, Sun J, An MX, Li S, Yan J and Wang HQ: BAG3 regulates stability of IL-8 mRNA via interplay between HuR and miR-4312 in PDACs. Cell Death Dis. 9(863)2018.PubMed/NCBI View Article : Google Scholar

31 

Li N, Chen M, Cao Y, Li H, Zhao J, Zhai Z, Ren F and Li K: Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer. BMC Cancer. 18(793)2018.PubMed/NCBI View Article : Google Scholar

32 

Lin D, Lin H and Xiong X: Expression and role of BAG-1 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps. Inflammation. 37:1912–1918. 2014.PubMed/NCBI View Article : Google Scholar

33 

Ying Z, Haiyan G and Haidong G: BAG5 regulates PTEN stability in MCF-7 cell line. BMB Rep. 46:490–494. 2013.PubMed/NCBI View Article : Google Scholar

34 

Rogers R, Dharsee M, Ackloo S and Flanagan JG: Proteomics analyses of activated human optic nerve head lamina cribrosa cells following biomechanical strain. Invest Ophthalmol Vis Sci. 53:3806–3016. 2012.PubMed/NCBI View Article : Google Scholar

35 

Bi L, Yang Q, Yuan J, Miao Q, Duan L, Li F and Wang S: MicroRNA-127-3p acts as a tumor suppressor in epithelial ovarian cancer by regulating the BAG5 gene. Oncol Rep. 36:2563–2570. 2016.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Lu J, Gu B, Lu W, Liu J and Lu J: miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5. Exp Ther Med 22: 1425, 2021.
APA
Lu, J., Gu, B., Lu, W., Liu, J., & Lu, J. (2021). miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5. Experimental and Therapeutic Medicine, 22, 1425. https://doi.org/10.3892/etm.2021.10860
MLA
Lu, J., Gu, B., Lu, W., Liu, J., Lu, J."miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5". Experimental and Therapeutic Medicine 22.6 (2021): 1425.
Chicago
Lu, J., Gu, B., Lu, W., Liu, J., Lu, J."miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1425. https://doi.org/10.3892/etm.2021.10860
Copy and paste a formatted citation
x
Spandidos Publications style
Lu J, Gu B, Lu W, Liu J and Lu J: miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5. Exp Ther Med 22: 1425, 2021.
APA
Lu, J., Gu, B., Lu, W., Liu, J., & Lu, J. (2021). miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5. Experimental and Therapeutic Medicine, 22, 1425. https://doi.org/10.3892/etm.2021.10860
MLA
Lu, J., Gu, B., Lu, W., Liu, J., Lu, J."miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5". Experimental and Therapeutic Medicine 22.6 (2021): 1425.
Chicago
Lu, J., Gu, B., Lu, W., Liu, J., Lu, J."miR‑142‑5p regulates lipopolysaccharide‑induced bovine epithelial cell proliferation and apoptosis via targeting BAG5". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1425. https://doi.org/10.3892/etm.2021.10860
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team