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Management of psoriasis in children (Review)

  • Authors:
    • Daciana Elena Branisteanu
    • Simona Georgescu
    • Ionela Lacramioara Serban
    • Alin Constantin Pinzariu
    • Daniel Boda
    • Minela Aida Maranduca
    • Mihai Glod
    • Catalina Ioana Branisteanu
    • Roxana Bilibau
    • Andreea  Dimitriu
    • Alin Codrut Nicolescu
    • Daniel Constantin Branisteanu
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Department of Dermatology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Physiology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Department of Surgery, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Department of Dermatology, ‘Railway Clinical Hospital’, 700506 Iasi, Romania, Department of Dermatology, ‘Arcadia Hospitals and Medical Centers’, 700620 Iasi, Romania, Department of Dermatology, Roma Medical Center for Diagnosis and Treatment, 011773 Bucharest, Romania, Department of Ophthalmology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania
    Copyright: © Branisteanu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 1429
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    Published online on: October 11, 2021
       https://doi.org/10.3892/etm.2021.10864
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Abstract

Psoriasis is a common long‑lasting, inflammatory disease that mainly affects the skin. The incidence of this condition has increased significantly over time and at this point, it affects approximately 1% of children. Psoriasis can appear at any age, including childhood and adolescence, with a higher frequency in girls, an earlier onset being associated with severe psoriasis. The pathology is the result of the interaction between genetics and trigger factors such as infections, stress, diet, obesity, and chemical irritants. Paradoxically, tumor necrosis factor (TNF)‑α inhibitors (infliximab, adalimumab) may induce psoriasis in children. Psoriasis is a long‑term condition with periods of exacerbation; thus, the quality of life can be affected and patients should receive psychosocial support. Although most children have mild disease and topical treatment is efficient, some cases are challenging to treat. The aim of this review was to provide an overview of the current knowledge concerning the epidemiology, etiology, pathogenesis, clinical features, comorbidities, and treatment of psoriasis in children and also to emphasize the need for a multidisciplinary approach to this complex pathology.
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Copy and paste a formatted citation
Spandidos Publications style
Branisteanu DE, Georgescu S, Serban IL, Pinzariu AC, Boda D, Maranduca MA, Glod M, Branisteanu CI, Bilibau R, Dimitriu A, Dimitriu A, et al: Management of psoriasis in children (Review). Exp Ther Med 22: 1429, 2021.
APA
Branisteanu, D.E., Georgescu, S., Serban, I.L., Pinzariu, A.C., Boda, D., Maranduca, M.A. ... Branisteanu, D.C. (2021). Management of psoriasis in children (Review). Experimental and Therapeutic Medicine, 22, 1429. https://doi.org/10.3892/etm.2021.10864
MLA
Branisteanu, D. E., Georgescu, S., Serban, I. L., Pinzariu, A. C., Boda, D., Maranduca, M. A., Glod, M., Branisteanu, C. I., Bilibau, R., Dimitriu, A., Nicolescu, A. C., Branisteanu, D. C."Management of psoriasis in children (Review)". Experimental and Therapeutic Medicine 22.6 (2021): 1429.
Chicago
Branisteanu, D. E., Georgescu, S., Serban, I. L., Pinzariu, A. C., Boda, D., Maranduca, M. A., Glod, M., Branisteanu, C. I., Bilibau, R., Dimitriu, A., Nicolescu, A. C., Branisteanu, D. C."Management of psoriasis in children (Review)". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1429. https://doi.org/10.3892/etm.2021.10864
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Spandidos Publications style
Branisteanu DE, Georgescu S, Serban IL, Pinzariu AC, Boda D, Maranduca MA, Glod M, Branisteanu CI, Bilibau R, Dimitriu A, Dimitriu A, et al: Management of psoriasis in children (Review). Exp Ther Med 22: 1429, 2021.
APA
Branisteanu, D.E., Georgescu, S., Serban, I.L., Pinzariu, A.C., Boda, D., Maranduca, M.A. ... Branisteanu, D.C. (2021). Management of psoriasis in children (Review). Experimental and Therapeutic Medicine, 22, 1429. https://doi.org/10.3892/etm.2021.10864
MLA
Branisteanu, D. E., Georgescu, S., Serban, I. L., Pinzariu, A. C., Boda, D., Maranduca, M. A., Glod, M., Branisteanu, C. I., Bilibau, R., Dimitriu, A., Nicolescu, A. C., Branisteanu, D. C."Management of psoriasis in children (Review)". Experimental and Therapeutic Medicine 22.6 (2021): 1429.
Chicago
Branisteanu, D. E., Georgescu, S., Serban, I. L., Pinzariu, A. C., Boda, D., Maranduca, M. A., Glod, M., Branisteanu, C. I., Bilibau, R., Dimitriu, A., Nicolescu, A. C., Branisteanu, D. C."Management of psoriasis in children (Review)". Experimental and Therapeutic Medicine 22, no. 6 (2021): 1429. https://doi.org/10.3892/etm.2021.10864
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