Open Access

Metabolic comorbidities of psoriasis (Review)

  • Authors:
    • Daciana Elena Branisteanu
    • Ruxandra Angela Pirvulescu
    • Alina Elena Spinu
    • Elena Andrese Porumb
    • Mihaela Cojocaru
    • Alin Codrut Nicolescu
    • Daniel Constantin Branisteanu
    • Catalina Ioana Branisteanu
    • Andreea Dimitriu
    • Anisia Iuliana Alexa
    • Mihaela Paula Toader
  • View Affiliations

  • Published online on: December 28, 2021     https://doi.org/10.3892/etm.2021.11102
  • Article Number: 179
  • Copyright: © Branisteanu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Psoriasis is a chronic inflammatory and immune‑mediated condition, which is no longer considered as being limited to the skin, but may affect the entire body. Epidemiological studies have shown that certain disorders, including obesity, diabetes, liver abnormalities, elevated lipid levels in the blood and metabolic syndrome, may occur more frequently in patients with psoriasis compared with the general population. As psoriasis is a chronic disease, the frequently associated comorbidities must be identified early to ensure timely treatment and, possibly, their prevention. Comorbidities often manifest clinically 1‑2 years after the onset of psoriasis and are commonly seen in patients with severe forms of the disease. The association between psoriasis and its comorbidities is not coincidental, but rather based on common pathophysiological mechanisms and risk factors that underlie the increased frequency of comorbidities in patients with psoriasis. The aim of the present review was to emphasize the important role of dermatologists in the early recognition of comorbidities in patients with psoriasis, with a focus on metabolic comorbidities, precisely because the dermatologists are usually the first medical contact due to the predominance of skin lesions. Therefore, these specialists have the responsibility to inform patients on the association between psoriasis and possible multiple comorbidities, devise prevention and treatment plans, or even redirect patients to other specialists.
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February-2022
Volume 23 Issue 2

Print ISSN: 1792-0981
Online ISSN:1792-1015

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Spandidos Publications style
Branisteanu DE, Pirvulescu RA, Spinu AE, Porumb EA, Cojocaru M, Nicolescu AC, Branisteanu DC, Branisteanu CI, Dimitriu A, Alexa AI, Alexa AI, et al: Metabolic comorbidities of psoriasis (Review). Exp Ther Med 23: 179, 2022
APA
Branisteanu, D.E., Pirvulescu, R.A., Spinu, A.E., Porumb, E.A., Cojocaru, M., Nicolescu, A.C. ... Toader, M.P. (2022). Metabolic comorbidities of psoriasis (Review). Experimental and Therapeutic Medicine, 23, 179. https://doi.org/10.3892/etm.2021.11102
MLA
Branisteanu, D. E., Pirvulescu, R. A., Spinu, A. E., Porumb, E. A., Cojocaru, M., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dimitriu, A., Alexa, A. I., Toader, M. P."Metabolic comorbidities of psoriasis (Review)". Experimental and Therapeutic Medicine 23.2 (2022): 179.
Chicago
Branisteanu, D. E., Pirvulescu, R. A., Spinu, A. E., Porumb, E. A., Cojocaru, M., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dimitriu, A., Alexa, A. I., Toader, M. P."Metabolic comorbidities of psoriasis (Review)". Experimental and Therapeutic Medicine 23, no. 2 (2022): 179. https://doi.org/10.3892/etm.2021.11102