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Metabolic comorbidities of psoriasis (Review)

  • Authors:
    • Daciana Elena Branisteanu
    • Ruxandra Angela Pirvulescu
    • Alina Elena Spinu
    • Elena Andrese Porumb
    • Mihaela Cojocaru
    • Alin Codrut Nicolescu
    • Daniel Constantin Branisteanu
    • Catalina Ioana Branisteanu
    • Andreea Dimitriu
    • Anisia Iuliana Alexa
    • Mihaela Paula Toader
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Department of Ophthalmology, ‘Carol Davila’ University of Medicine and Pharmacy, 050474 Bucharest, Romania, Department of Dermatology, Railway Clinical Hospital, 700506 Iasi, Romania, Department of Dermatology, ‘Sf. Spiridon’ Clinical Emergency County Hospital, 700111 Iasi, Romania, Department of Dermatology, ‘Roma’ Medical Center for Diagnosis and Treatment, 011773 Bucharest, Romania, Department of Ophthalmology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Faculty of Medicine, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania, Department of Dermatology, ‘Arcadia’ Hospitals and Medical Centers, 700620 Iasi, Romania, Department of Oral Dermatology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania
    Copyright: © Branisteanu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 179
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    Published online on: December 28, 2021
       https://doi.org/10.3892/etm.2021.11102
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Abstract

Psoriasis is a chronic inflammatory and immune‑mediated condition, which is no longer considered as being limited to the skin, but may affect the entire body. Epidemiological studies have shown that certain disorders, including obesity, diabetes, liver abnormalities, elevated lipid levels in the blood and metabolic syndrome, may occur more frequently in patients with psoriasis compared with the general population. As psoriasis is a chronic disease, the frequently associated comorbidities must be identified early to ensure timely treatment and, possibly, their prevention. Comorbidities often manifest clinically 1‑2 years after the onset of psoriasis and are commonly seen in patients with severe forms of the disease. The association between psoriasis and its comorbidities is not coincidental, but rather based on common pathophysiological mechanisms and risk factors that underlie the increased frequency of comorbidities in patients with psoriasis. The aim of the present review was to emphasize the important role of dermatologists in the early recognition of comorbidities in patients with psoriasis, with a focus on metabolic comorbidities, precisely because the dermatologists are usually the first medical contact due to the predominance of skin lesions. Therefore, these specialists have the responsibility to inform patients on the association between psoriasis and possible multiple comorbidities, devise prevention and treatment plans, or even redirect patients to other specialists.
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Copy and paste a formatted citation
Spandidos Publications style
Branisteanu DE, Pirvulescu RA, Spinu AE, Porumb EA, Cojocaru M, Nicolescu AC, Branisteanu DC, Branisteanu CI, Dimitriu A, Alexa AI, Alexa AI, et al: Metabolic comorbidities of psoriasis (Review). Exp Ther Med 23: 179, 2022.
APA
Branisteanu, D.E., Pirvulescu, R.A., Spinu, A.E., Porumb, E.A., Cojocaru, M., Nicolescu, A.C. ... Toader, M.P. (2022). Metabolic comorbidities of psoriasis (Review). Experimental and Therapeutic Medicine, 23, 179. https://doi.org/10.3892/etm.2021.11102
MLA
Branisteanu, D. E., Pirvulescu, R. A., Spinu, A. E., Porumb, E. A., Cojocaru, M., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dimitriu, A., Alexa, A. I., Toader, M. P."Metabolic comorbidities of psoriasis (Review)". Experimental and Therapeutic Medicine 23.2 (2022): 179.
Chicago
Branisteanu, D. E., Pirvulescu, R. A., Spinu, A. E., Porumb, E. A., Cojocaru, M., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dimitriu, A., Alexa, A. I., Toader, M. P."Metabolic comorbidities of psoriasis (Review)". Experimental and Therapeutic Medicine 23, no. 2 (2022): 179. https://doi.org/10.3892/etm.2021.11102
Copy and paste a formatted citation
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Spandidos Publications style
Branisteanu DE, Pirvulescu RA, Spinu AE, Porumb EA, Cojocaru M, Nicolescu AC, Branisteanu DC, Branisteanu CI, Dimitriu A, Alexa AI, Alexa AI, et al: Metabolic comorbidities of psoriasis (Review). Exp Ther Med 23: 179, 2022.
APA
Branisteanu, D.E., Pirvulescu, R.A., Spinu, A.E., Porumb, E.A., Cojocaru, M., Nicolescu, A.C. ... Toader, M.P. (2022). Metabolic comorbidities of psoriasis (Review). Experimental and Therapeutic Medicine, 23, 179. https://doi.org/10.3892/etm.2021.11102
MLA
Branisteanu, D. E., Pirvulescu, R. A., Spinu, A. E., Porumb, E. A., Cojocaru, M., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dimitriu, A., Alexa, A. I., Toader, M. P."Metabolic comorbidities of psoriasis (Review)". Experimental and Therapeutic Medicine 23.2 (2022): 179.
Chicago
Branisteanu, D. E., Pirvulescu, R. A., Spinu, A. E., Porumb, E. A., Cojocaru, M., Nicolescu, A. C., Branisteanu, D. C., Branisteanu, C. I., Dimitriu, A., Alexa, A. I., Toader, M. P."Metabolic comorbidities of psoriasis (Review)". Experimental and Therapeutic Medicine 23, no. 2 (2022): 179. https://doi.org/10.3892/etm.2021.11102
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