Bacterial endocarditis masked by COVID‑19: A case report

Bajdechi,Mircea; Vlad,Nicoleta Dorina; Dumitrascu,Mirela; Mocanu,Elena; Dumitru,Irina Magdalena; Cernat,Roxana Carmen; Rugină,Sorin

doi:10.3892/etm.2021.11109

February-2022 Volume 23 Issue 2

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February-2022 Volume 23 Issue 2

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Case Report

Bacterial endocarditis masked by COVID‑19: A case report

Authors:
- Mircea Bajdechi
- Nicoleta Dorina Vlad
- Mirela Dumitrascu
- Elena Mocanu
- Irina Magdalena Dumitru
- Roxana Carmen Cernat
- Sorin Rugină
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Affiliations: Doctoral School of Medicine, ‘Ovidius’ University, 900470 Constanta, Romania, Department of Infectious Disease, Clinical Infectious Diseases Hospital, 900709 Constanta, Romania, Department of Public Health, Faculty of Medicine, ‘Ovidius’ University, 900470 Constanta, Romania
Article Number: 186
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Published online on: December 30, 2021

https://doi.org/10.3892/etm.2021.11109
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Abstract

Infective endocarditis represents a rare complication among patients infected with severe acute respiratory syndrome coronavirus‑2 (SARS‑CoV‑2); it is often a nosocomial infection and the symptomatology can be masked by respiratory failure symptoms from SARS‑CoV‑2 bronchopneumonia. Management of patients with severe forms of SARS‑COV‑2 infection who also have associated infective endocarditis is very difficult, especially in mono‑specialty hospitals (such as infectious diseases hospitals) where access to cardiological investigations is limited. The current study presents the case of a 73‑year‑old woman with increased cardiovascular risk (high blood pressure, diabetes mellitus and obesity), with uninvestigated ischaemic heart disease, who was admitted to the Department of Infectious Diseases in the Clinical Infectious Diseases Hospital (Constanta, Romania) due to SARS‑CoV‑2. Although the evolution was initially favorable, the condition of the patient significantly deteriorated on the 14th day of hospitalization due to the development of Enterococcus faecium infective endocarditis. Despite the therapy, the evolution was fulminant. Infection with coronavirus disease 2019 can result in numerous comorbidities, which cause higher mortality rates than in the general population.

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1	Momtazmanesh S, Shobeiri P, Hanaei S, Mahmoud-Elsayed H, Dalvi B and Malakan EM: Cardiovascular disease in COVID-19: A systematic review and meta-analysis of 10,898 patients and proposal of a triage risk stratification tool. Egypt Heart J. 72(41)2020.PubMed/NCBI View Article : Google Scholar
2	Hessami A, Shamshirian A, Heydari K, Pourali F, Alizadeh-Navaei R, Moosazadeh M, Abrotan S, Shojaie L, Sedighi S, Shamshirian D and Rezaei N: Cardiovascular diseases burden in COVID-19: Systematic review and meta-analysis. Am J Emerg Med. 46:382–391. 2020.PubMed/NCBI View Article : Google Scholar
3	Linschoten M, Peters S, van Smeden M, Jewbali LS, Schaap J, Siebelink HM, Smits PC, Tieleman RG, van der Harst P, van Gilst WH, et al: Cardiac complications in patients hospitalised with COVID-19. Eur Heart J Acute Cardiovasc Care. 9:817–823. 2020.PubMed/NCBI View Article : Google Scholar
4	Li JS, Sexton DJ, Mick N, Nettles R, Fowler VG Jr, Ryan T, Bashore T and Corey GR: Proposed modifications to the duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 30:633–638. 2000.PubMed/NCBI View Article : Google Scholar
5	Ramos-Martínez A, Fernández-Cruz A, Domínguez F, Forteza A, Cobo M, Sánchez-Romero I and Asensio A: Hospital-acquired infective endocarditis during Covid-19 pandemic. Infect Prev Pract. 2(100080)2020.PubMed/NCBI View Article : Google Scholar
6	Erdem H, Puca E, Ruch Y, Santos L, Ghanem-Zoubi N, Argemi X, Hansmann Y, Guner R, Tonziello G, Mazzucotelli JP, et al: Portraying infective endocarditis: Results of multinational ID-IRI study. Eur J Clin Microbiol Infect Dis. 38:1753–1763. 2019.PubMed/NCBI View Article : Google Scholar
7	Hayes DE, Rhee DW, Hisamoto K, Smith D, Ro R, Vainrib AF, Bamira D, Zhou F and Saric M: Two cases of acute endocarditis misdiagnosed as COVID-19 infection. Echocardiography. 38:798–804. 2021.PubMed/NCBI View Article : Google Scholar
8	Amir M, Djaharuddin I, Sudharsono A and Ramadanyd S: COVID-19 concomitant with infective endocarditis: A case report and review of management. Int J Infect Dis. 98:109–112. 2020.PubMed/NCBI View Article : Google Scholar
9	Gurghean AL, Savulescu-Fiedler I and Mihailescu A: Multiple cardiac complications after adjuvant therapy for breast cancer: The importance of echocardiography. A case report and review of the literature. Med Ultrason. 19:117–120. 2017.PubMed/NCBI View Article : Google Scholar
10	Streinu-Cercel A, Săndulescu O, Poiană C, Dorobanţu M, Mircescu G, Lăzureanu VE, Dumitru IM, Chirilă O and Streinu-Cercel A: Extended Consensus Group. Consensus statement on the assessment of comorbidities in people living with HIV in Romania. Germs. 9:198–210. 2019.PubMed/NCBI View Article : Google Scholar
11	Dumitru IM, Lilios G and Arbune M: Respiratory infections and air pollution, retrospective study over the past 10 years. J Environ Prot Ecol. 19:1445–1451. 2018.
12	Calina D, Docea AO, Petrakis D, Egorov AM, Ishmukhametov AA, Gabibov AG, Shtilman MI, Kostoff R, Carvalho F, Vinceti M, et al: Towards effective COVID-19 vaccines: Updates, perspectives and challenges (Review). Int J Mol Med. 46:3–16. 2020.PubMed/NCBI View Article : Google Scholar
13	Docea AO, Tsatsakis A, Albulescu D, Cristea O, Zlatian O, Vinceti M, Moschos SA, Tsoukalas D, Goumenou M, Drakoulis N, et al: A new threat from an old enemy: Re-emergence of coronavirus (Review). Int J Mol Med. 45:1631–1643. 2020.PubMed/NCBI View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Bacterial endocarditis masked by COVID‑19: A case report

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